7SGQ

Protease inhibitors variant, CTI-homolog pacifastin

External Resource: Annotation

Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2B Superfamily	PMP inhibitors	8035936	3000534	SCOP2B (2022-06-29)
B	SCOP2B Superfamily	PMP inhibitors	8035936	3000534	SCOP2B (2022-06-29)
C	SCOP2B Superfamily	PMP inhibitors	8035936	3000534	SCOP2B (2022-06-29)
D	SCOP2B Superfamily	PMP inhibitors	8035936	3000534	SCOP2B (2022-06-29)
E	SCOP2B Superfamily	PMP inhibitors	8035936	3000534	SCOP2B (2022-06-29)
F	SCOP2B Superfamily	PMP inhibitors	8035936	3000534	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	PF05375	e7sgqA1	A: few secondary structure elements	X: PMP inhibitors (From Topology)	H: PMP inhibitors (From Topology)	T: PMP inhibitors	F: PF05375	ECOD (1.6)
B	PF05375	e7sgqB1	A: few secondary structure elements	X: PMP inhibitors (From Topology)	H: PMP inhibitors (From Topology)	T: PMP inhibitors	F: PF05375	ECOD (1.6)
C	PF05375	e7sgqC1	A: few secondary structure elements	X: PMP inhibitors (From Topology)	H: PMP inhibitors (From Topology)	T: PMP inhibitors	F: PF05375	ECOD (1.6)
D	PF05375	e7sgqD1	A: few secondary structure elements	X: PMP inhibitors (From Topology)	H: PMP inhibitors (From Topology)	T: PMP inhibitors	F: PF05375	ECOD (1.6)
E	PF05375	e7sgqE1	A: few secondary structure elements	X: PMP inhibitors (From Topology)	H: PMP inhibitors (From Topology)	T: PMP inhibitors	F: PF05375	ECOD (1.6)
F	PF05375	e7sgqF1	A: few secondary structure elements	X: PMP inhibitors (From Topology)	H: PMP inhibitors (From Topology)	T: PMP inhibitors	F: PF05375	ECOD (1.6)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B, C, D, E A, B, C, D, E, F	PF05375	Pacifastin inhibitor (LCMII) (Pacifastin_I)	Pacifastin inhibitor (LCMII)	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B, C, D, E A, B, C, D, E, F	Protease inhibitor LCMI-II	enzyme regulator activity molecular function inhibitor activity peptidase regulator activity serine-type endopeptidase inhibitor activity molecular function regulator activity enzyme inhibitor activity peptidase inhibitor activity endopeptidase regulator activity endopeptidase inhibitor activity	-	extracellular region cellular anatomical entity

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B, C, D, E A, B, C, D, E, F	IPR008037	Pacifastin domain	Domain
A, B, C, D, E A, B, C, D, E, F	IPR036201	Pacifastin domain superfamily	Homologous Superfamily
A, B, C, D, E A, B, C, D, E, F	IPR016307	Protease inhibitor with pacifastin repeats	Family

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.