7NZZ
Ras1 guanine nucleotide exchange factor Cdc25 (REM and catalytic domains)
Domain Annotation: ECOD Classification ECOD Database Homepage
Chains | Family Name | Domain Identifier | Architecture | Possible Homology | Homology | Topology | Family | Provenance Source (Version) |
---|---|---|---|---|---|---|---|---|
A | PF00617,PF00618 | e7nzzA1 | A: alpha superhelices | X: Repetitive alpha hairpins | H: Ras GEF (From Topology) | T: Ras GEF | F: PF00617,PF00618 | ECOD (1.6) |
B | PF00617,PF00618 | e7nzzB1 | A: alpha superhelices | X: Repetitive alpha hairpins | H: Ras GEF (From Topology) | T: Ras GEF | F: PF00617,PF00618 | ECOD (1.6) |
Protein Family Annotation Pfam Database Homepage
Chains | Accession | Name | Description | Comments | Source |
---|---|---|---|---|---|
PF00617 | RasGEF domain (RasGEF) | RasGEF domain | - | Family | |
PF00618 | RasGEF N-terminal motif (RasGEF_N) | RasGEF N-terminal motif | A subset of guanine nucleotide exchange factor for Ras-like small GTPases appear to possess this motif/domain N-terminal to the RasGef (Cdc25-like) domain. | Domain |
Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage
InterPro: Protein Family Classification InterPro Database Homepage
Chains | Accession | Name | Type |
---|---|---|---|
IPR008937 | Ras-like guanine nucleotide exchange factor | Family | |
IPR019804 | Ras guanine-nucleotide exchange factor, conserved site | Conserved Site | |
IPR000651 | Ras-like guanine nucleotide exchange factor, N-terminal | Domain | |
IPR001452 | SH3 domain | Domain | |
IPR036028 | SH3-like domain superfamily | Homologous Superfamily | |
IPR036964 | Ras guanine-nucleotide exchange factor, catalytic domain superfamily | Homologous Superfamily | |
IPR023578 | Ras guanine nucleotide exchange factor domain superfamily | Homologous Superfamily | |
IPR001895 | Ras guanine-nucleotide exchange factors catalytic domain | Domain |