7MQA
Cryo-EM structure of the human SSU processome, state post-A1
Domain Annotation: SCOP2 Classification SCOP2 Database Homepage
Chains | Type | Family Name | Domain Identifier | Family Identifier | Provenance Source (Version) |
---|---|---|---|---|---|
E [auth L4] | SCOP2B Superfamily | Translation proteins SH3-like KOW motif containing domain | 8052757 | 3000334 | SCOP2B (2022-06-29) |
E [auth L4] | SCOP2B Superfamily | Alpha-L RNA-binding motif | 8052755 | 3001473 | SCOP2B (2022-06-29) |
E [auth L4] | SCOP2B Superfamily | Nucleic acid-binding proteins | 8052756 | 3000135 | SCOP2B (2022-06-29) |
I [auth L8] | SCOP2B Superfamily | 50S Ribosomal protein L14-like | 8053077 | 3000433 | SCOP2B (2022-06-29) |
K [auth LA] | SCOP2B Superfamily | L30e-like | 8063978 | 3001739 | SCOP2B (2022-06-29) |
L [auth LC] | SCOP2B Superfamily | Ribosomal protein S5 domain 2-like | 8082685 | 3000100 | SCOP2B (2022-06-29) |
M [auth LD] | SCOP2B Superfamily | Ribosomal S17 N-terminal domain-like | 8052715 | 3002138 | SCOP2B (2022-06-29) |
M [auth LD] | SCOP2B Superfamily | Nucleic acid-binding proteins | 8052717 | 3000135 | SCOP2B (2022-06-29) |
O [auth LG] | SCOP2B Superfamily | Nucleic acid-binding proteins | 8063426 | 3000135 | SCOP2B (2022-06-29) |
JA [auth NF] | SCOP2B Superfamily | S15/NS1 RNA-binding domain | 8052959 | 3001284 | SCOP2B (2022-06-29) |
JA [auth NF] | SCOP2B Superfamily | Homeodomain-like | 8052958 | 3000001 | SCOP2B (2022-06-29) |
NA [auth NL] | SCOP2B Superfamily | S-adenosyl-L-methionine-dependent methyltransferases | 8036137 | 3000118 | SCOP2B (2022-06-29) |
NA [auth NL] | SCOP2B Superfamily | S13-like H2TH domain | 8090728 | 3000053 | SCOP2B (2022-06-29) |
OA [auth NM] | SCOP2B Superfamily | Ribosomal S3Ae-like | 8053212 | 3002166 | SCOP2B (2022-06-29) |
QA [auth NP] | SCOP2B Superfamily | Winged helix DNA-binding domain | 8089318 | 3000034 | SCOP2B (2022-06-29) |
AB [auth SD] | SCOP2B Superfamily | S-adenosyl-L-methionine-dependent methyltransferases | 8063658 | 3000118 | SCOP2B (2022-06-29) |
ZA [auth SC] | SCOP2B Superfamily | S-adenosyl-L-methionine-dependent methyltransferases | 8063658 | 3000118 | SCOP2B (2022-06-29) |
BB [auth SE] | SCOP2B Superfamily | L30e-like | 8043738 | 3001739 | SCOP2B (2022-06-29) |
CB [auth SF] | SCOP2B Superfamily | L30e-like | 8043738 | 3001739 | SCOP2B (2022-06-29) |
KA [auth NG] | SCOP2B Superfamily | Translational machinery components | 8098844 | 3000571 | SCOP2B (2022-06-29) |
PA [auth NO] | SCOP2B Superfamily | Ribosomal protein S8 | 8095469 | 3000709 | SCOP2B (2022-06-29) |
GB [auth SJ] | SCOP2B Superfamily | alpha/beta knot | 8084459 | 3001122 | SCOP2B (2022-06-29) |
HB [auth SK] | SCOP2B Superfamily | alpha/beta knot | 8084459 | 3001122 | SCOP2B (2022-06-29) |
F [auth L5] | SCOP2B Superfamily | Ribosomal protein S7 | 8066003 | 3000799 | SCOP2B (2022-06-29) |
G [auth L6] | SCOP2B Superfamily | GS N-terminal domain-like | 8053171 | 3000408 | SCOP2B (2022-06-29) |
Domain Annotation: ECOD Classification ECOD Database Homepage
Chains | Family Name | Domain Identifier | Architecture | Possible Homology | Homology | Topology | Family | Provenance Source (Version) |
---|---|---|---|---|---|---|---|---|
D [auth L3] | PF00416 | e7mqaL31 | A: alpha arrays | X: HhH/H2TH | H: H2TH (From Topology) | T: H2TH | F: PF00416 | ECOD (1.6) |
E [auth L4] | PF00900 | e7mqaL41 | A: beta barrels | X: OB-fold | H: Nucleic acid-binding proteins (From Topology) | T: Nucleic acid-binding proteins | F: PF00900 | ECOD (1.6) |
E [auth L4] | PF00467,PF16121 | e7mqaL43 | A: beta barrels | X: SH3 | H: SH3 | T: SH3 | F: PF00467,PF16121 | ECOD (1.6) |
E [auth L4] | PF00900,PF01479,PF08071 | e7mqaL42 | A: a+b two layers | X: beta-Grasp | H: Ubiquitin-related | T: Alpha-L RNA-binding motif | F: PF00900,PF01479,PF08071 | ECOD (1.6) |
H [auth L7] | PF01251 | e7mqaL71 | A: a+b two layers | X: Alpha-lytic protease prodomain-like | H: 40S ribosomal protein S7-A (From Topology) | T: 40S ribosomal protein S7-A | F: PF01251 | ECOD (1.6) |
I [auth L8] | PF01201 | e7mqaL81 | A: beta barrels | X: Ribosomal protein L14-like | H: Ribosomal protein L14-related (From Topology) | T: Ribosomal protein L14-related | F: PF01201 | ECOD (1.6) |
J [auth L9] | PF00163,PF01479 | e7mqaL91 | A: a+b two layers | X: beta-Grasp | H: Ubiquitin-related | T: Alpha-L RNA-binding motif | F: PF00163,PF01479 | ECOD (1.6) |
K [auth LA] | PF01248 | e7mqaLA1 | A: a+b three layers | X: Bacillus chorismate mutase-like | H: L30e-like (From Topology) | T: L30e-like | F: PF01248 | ECOD (1.6) |
L [auth LC] | PF00380 | e7mqaLC1 | A: a+b two layers | X: Ribosomal protein S5 domain 2-like (From Topology) | H: Ribosomal protein S5 domain 2-like (From Topology) | T: Ribosomal protein S5 domain 2-like | F: PF00380 | ECOD (1.6) |
M [auth LD] | PF00366,PF16205 | e7mqaLD1 | A: beta barrels | X: OB-fold | H: Nucleic acid-binding proteins (From Topology) | T: Nucleic acid-binding proteins | F: PF00366,PF16205 | ECOD (1.6) |
N [auth LF] | PF01282 | e7mqaLF1 | A: a+b two layers | X: Alpha-beta plaits | H: Ribosomal proteins S24e, L23 and L15e (From Topology) | T: Ribosomal proteins S24e, L23 and L15e | F: PF01282 | ECOD (1.6) |
O [auth LG] | PF01200 | e7mqaLG1 | A: beta barrels | X: OB-fold | H: Nucleic acid-binding proteins (From Topology) | T: Nucleic acid-binding proteins | F: PF01200 | ECOD (1.6) |
R [auth LJ] | PF00400 | e7mqaLJ1 | A: beta duplicates or obligate multimers | X: beta-propeller-like | H: beta-propeller | T: 8-bladed | F: PF00400 | ECOD (1.6) |
R [auth LJ] | PF09384 | e7mqaLJ2 | A: alpha superhelices | X: Repetitive alpha hairpins | H: C-terminal tetramerization domain of Utp1/Utp21/Utp12/Utp13 (From Topology) | T: C-terminal tetramerization domain of Utp1/Utp21/Utp12/Utp13 | F: PF09384 | ECOD (1.6) |
S [auth LK] | PF04003 | e7mqaLK1 | A: alpha superhelices | X: Repetitive alpha hairpins | H: C-terminal tetramerization domain of Utp1/Utp21/Utp12/Utp13 (From Topology) | T: C-terminal tetramerization domain of Utp1/Utp21/Utp12/Utp13 | F: PF04003 | ECOD (1.6) |
V [auth LN] | F_UNCLASSIFIED | e7mqaLN1 | A: beta duplicates or obligate multimers | X: beta-propeller-like | H: beta-propeller | T: 7-bladed | F: F_UNCLASSIFIED | ECOD (1.6) |
V [auth LN] | PF00400 | e7mqaLN2 | A: beta duplicates or obligate multimers | X: beta-propeller-like | H: beta-propeller | T: 7-bladed | F: PF00400 | ECOD (1.6) |
W [auth LO] | F_UNCLASSIFIED | e7mqaLO1 | A: beta duplicates or obligate multimers | X: beta-propeller-like | H: beta-propeller | T: 7-bladed | F: F_UNCLASSIFIED | ECOD (1.6) |
W [auth LO] | PF00400 | e7mqaLO2 | A: beta duplicates or obligate multimers | X: beta-propeller-like | H: beta-propeller | T: 7-bladed | F: PF00400 | ECOD (1.6) |
W [auth LO] | PF04003 | e7mqaLO3 | A: alpha superhelices | X: Repetitive alpha hairpins | H: C-terminal tetramerization domain of Utp1/Utp21/Utp12/Utp13 (From Topology) | T: C-terminal tetramerization domain of Utp1/Utp21/Utp12/Utp13 | F: PF04003 | ECOD (1.6) |
Y [auth LQ] | PF00400 | e7mqaLQ2 | A: beta duplicates or obligate multimers | X: beta-propeller-like | H: beta-propeller | T: 7-bladed | F: PF00400 | ECOD (1.6) |
Y [auth LQ] | PF04003 | e7mqaLQ1 | A: alpha superhelices | X: Repetitive alpha hairpins | H: C-terminal tetramerization domain of Utp1/Utp21/Utp12/Utp13 (From Topology) | T: C-terminal tetramerization domain of Utp1/Utp21/Utp12/Utp13 | F: PF04003 | ECOD (1.6) |
BA [auth LT] | PF00400 | e7mqaLT1 | A: beta duplicates or obligate multimers | X: beta-propeller-like | H: beta-propeller | T: 7-bladed | F: PF00400 | ECOD (1.6) |
BA [auth LT] | PF00400,PF12894 | e7mqaLT2 | A: beta duplicates or obligate multimers | X: beta-propeller-like | H: beta-propeller | T: 7-bladed | F: PF00400,PF12894 | ECOD (1.6) |
BA [auth LT] | PF04192 | e7mqaLT3 | A: alpha superhelices | X: Repetitive alpha hairpins | H: C-terminal tetramerization domain of Utp1/Utp21/Utp12/Utp13 (From Topology) | T: C-terminal tetramerization domain of Utp1/Utp21/Utp12/Utp13 | F: PF04192 | ECOD (1.6) |
JA [auth NF] | PF08069 | e7mqaNF1 | A: alpha arrays | X: HTH | H: 40S ribosomal protein S13 N-terminal domain (From Topology) | T: 40S ribosomal protein S13 N-terminal domain | F: PF08069 | ECOD (1.6) |
JA [auth NF] | PF00312 | e7mqaNF2 | A: alpha arrays | X: S15/NS1 RNA-binding domain (From Topology) | H: S15/NS1 RNA-binding domain (From Topology) | T: S15/NS1 RNA-binding domain | F: PF00312 | ECOD (1.6) |
LA [auth NH] | PF17403 | e7mqaNH5 | A: alpha arrays | X: HhH/H2TH | H: SAM/DNA-glycosylase | T: PAP/OAS1 substrate-binding domain | F: PF17403 | ECOD (1.6) |
LA [auth NH] | PF17406 | e7mqaNH2 | A: alpha arrays | X: HhH/H2TH | H: SAM/DNA-glycosylase | T: PAP/OAS1 substrate-binding domain | F: PF17406 | ECOD (1.6) |
LA [auth NH] | PF17404 | e7mqaNH4 | A: a+b two layers | X: Alpha-beta plaits | H: PAP/Archaeal CCA-adding enzyme, C-terminal domain (From Topology) | T: PAP/Archaeal CCA-adding enzyme, C-terminal domain | F: PF17404 | ECOD (1.6) |
LA [auth NH] | PF17407 | e7mqaNH6 | A: a+b two layers | X: Alpha-beta plaits | H: PAP/Archaeal CCA-adding enzyme, C-terminal domain (From Topology) | T: PAP/Archaeal CCA-adding enzyme, C-terminal domain | F: PF17407 | ECOD (1.6) |
LA [auth NH] | PF03813 | e7mqaNH1 | A: a+b three layers | X: Nucleotidyltransferase-like | H: Nucleotidyltransferase (From Topology) | T: Nucleotidyltransferase | F: PF03813 | ECOD (1.6) |
LA [auth NH] | PF17405 | e7mqaNH3 | A: a+b three layers | X: Nucleotidyltransferase-like | H: Nucleotidyltransferase (From Topology) | T: Nucleotidyltransferase | F: PF17405 | ECOD (1.6) |
NA [auth NL] | F_UNCLASSIFIED | e7mqaNL2 | A: alpha arrays | X: HhH/H2TH | H: H2TH (From Topology) | T: H2TH | F: F_UNCLASSIFIED | ECOD (1.6) |
NA [auth NL] | PF00398 | e7mqaNL1 | A: a/b three-layered sandwiches | X: Rossmann-like | H: Rossmann-related | T: S-adenosyl-L-methionine-dependent methyltransferases | F: PF00398 | ECOD (1.6) |
OA [auth NM] | PF01015 | e7mqaNM1 | A: beta barrels | X: Ribosomal protein L25-like | H: 40S ribosomal protein S3A N-terminal domain (From Topology) | T: 40S ribosomal protein S3A N-terminal domain | F: PF01015 | ECOD (1.6) |
OA [auth NM] | PF01015 | e7mqaNM2 | A: a+b two layers | X: T-fold | H: 40S ribosomal protein S3A C-terminal domain (From Topology) | T: 40S ribosomal protein S3A C-terminal domain | F: PF01015 | ECOD (1.6) |
QA [auth NP] | PF01090 | e7mqaNP1 | A: alpha arrays | X: HTH | H: HTH | T: winged | F: PF01090 | ECOD (1.6) |
VA [auth NU] | PF00833 | e7mqaNU1 | A: alpha arrays | X: HTH | H: HTH | T: FF domain | F: PF00833 | ECOD (1.6) |
AB [auth SD] | PF01269 | e7mqaSD1 | A: a/b three-layered sandwiches | X: Rossmann-like | H: Rossmann-related | T: S-adenosyl-L-methionine-dependent methyltransferases | F: PF01269 | ECOD (1.6) |
ZA [auth SC] | PF01269 | e7mqaSC1 | A: a/b three-layered sandwiches | X: Rossmann-like | H: Rossmann-related | T: S-adenosyl-L-methionine-dependent methyltransferases | F: PF01269 | ECOD (1.6) |
BB [auth SE] | PF01248 | e7mqaSE1 | A: a+b three layers | X: Bacillus chorismate mutase-like | H: L30e-like (From Topology) | T: L30e-like | F: PF01248 | ECOD (1.6) |
CB [auth SF] | PF01248 | e7mqaSF1 | A: a+b three layers | X: Bacillus chorismate mutase-like | H: L30e-like (From Topology) | T: L30e-like | F: PF01248 | ECOD (1.6) |
EB [auth SH] | PF01137 | e7mqaSH2 | A: a+b two layers | X: IF3-like | H: EPT/RTPC-like (From Topology) | T: EPT/RTPC-like | F: PF01137 | ECOD (1.6) |
EB [auth SH] | PF05189 | e7mqaSH1 | A: a+b three layers | X: Thioredoxin-like | H: RNA 3'-terminal phosphate cyclase, RPTC, insert domain (From Topology) | T: RNA 3'-terminal phosphate cyclase, RPTC, insert domain | F: PF05189 | ECOD (1.6) |
IB [auth SL] | PF04900 | e7mqaSL1 | A: a/b three-layered sandwiches | X: HAD domain-like | H: HAD domain-related | T: PIN domain-like | F: PF04900 | ECOD (1.6) |
QB [auth SW] | PF17903 | e7mqaSW2 | A: a+b two layers | X: Alpha-lytic protease prodomain-like | H: KH-domains | T: Eukaryotic type KH-domain (KH-domain type I) | F: PF17903 | ECOD (1.6) |
QB [auth SW] | PF22891 | e7mqaSW1 | A: a+b two layers | X: Alpha-lytic protease prodomain-like | H: KH-domains | T: Eukaryotic type KH-domain (KH-domain type I) | F: PF22891 | ECOD (1.6) |
X [auth LP] | PF08640 | e7mqaLP1 | A: alpha superhelices | X: Repetitive alpha hairpins | H: ARM repeat (From Topology) | T: ARM repeat | F: PF08640 | ECOD (1.6) |
Z [auth LR] | PF00400 | e7mqaLR2 | A: beta duplicates or obligate multimers | X: beta-propeller-like | H: beta-propeller | T: 7-bladed | F: PF00400 | ECOD (1.6) |
Z [auth LR] | PF00400 | e7mqaLR1 | A: beta duplicates or obligate multimers | X: beta-propeller-like | H: beta-propeller | T: 8-bladed | F: PF00400 | ECOD (1.6) |
Z [auth LR] | PF08625 | e7mqaLR3 | A: alpha superhelices | X: Repetitive alpha hairpins | H: C-terminal tetramerization domain of Utp1/Utp21/Utp12/Utp13 (From Topology) | T: C-terminal tetramerization domain of Utp1/Utp21/Utp12/Utp13 | F: PF08625 | ECOD (1.6) |
FA [auth LZ] | PF00163,PF01479 | e7mqaLZ1 | A: a+b two layers | X: beta-Grasp | H: Ubiquitin-related | T: Alpha-L RNA-binding motif | F: PF00163,PF01479 | ECOD (1.6) |
KA [auth NG] | PF00411 | e7mqaNG1 | A: mixed a+b and a/b | X: Ribonuclease H-like | H: Ribonuclease H-like (From Topology) | T: Ribonuclease H-like | F: PF00411 | ECOD (1.6) |
PA [auth NO] | PF00410 | e7mqaNO2 | A: a+b two layers | X: R3H domain-like | H: Ribosomal protein S8, N-terminal domain (From Topology) | T: Ribosomal protein S8, N-terminal domain | F: PF00410 | ECOD (1.6) |
PA [auth NO] | PF00410 | e7mqaNO1 | A: a+b two layers | X: Ribosomal protein S8, C-terminal domain (From Topology) | H: Ribosomal protein S8, C-terminal domain (From Topology) | T: Ribosomal protein S8, C-terminal domain | F: PF00410 | ECOD (1.6) |
RA [auth NQ] | PF01667 | e7mqaNQ1 | A: few secondary structure elements | X: Rubredoxin-like | H: Rubredoxin-related | T: Rubredoxin-related | F: PF01667 | ECOD (1.6) |
UA [auth NT] | PF01599 | e7mqaNT1 | A: few secondary structure elements | X: Rubredoxin-like | H: Rubredoxin-related | T: Rubredoxin-related | F: PF01599 | ECOD (1.6) |
XA [auth SA] | PF01798 | e7mqaSA1 | A: alpha arrays | X: HhH/H2TH | H: SAM/DNA-glycosylase | T: Nop C-terminal domain | F: PF01798 | ECOD (1.6) |
XA [auth SA] | PF01798 | e7mqaSA2 | A: alpha complex topology | X: Nop N-terminal domain (From Topology) | H: Nop N-terminal domain (From Topology) | T: Nop N-terminal domain | F: PF01798 | ECOD (1.6) |
XA [auth SA] | PF08156 | e7mqaSA3 | A: mixed a+b and a/b | X: Nop N-terminal domain (From Topology) | H: Nop N-terminal domain (From Topology) | T: Nop N-terminal domain | F: PF08156 | ECOD (1.6) |
GB [auth SJ] | PF03587 | e7mqaSJ1 | A: a/b three-layered sandwiches | X: alpha/beta knot (From Topology) | H: alpha/beta knot (From Topology) | T: alpha/beta knot | F: PF03587 | ECOD (1.6) |
HB [auth SK] | PF03587 | e7mqaSK1 | A: a/b three-layered sandwiches | X: alpha/beta knot (From Topology) | H: alpha/beta knot (From Topology) | T: alpha/beta knot | F: PF03587 | ECOD (1.6) |
F [auth L5] | PF00177 | e7mqaL51 | A: alpha arrays | X: Ribosomal protein S7 (From Topology) | H: Ribosomal protein S7 (From Topology) | T: Ribosomal protein S7 | F: PF00177 | ECOD (1.6) |
MB [auth SR] | PF00164 | e7mqaSR1 | A: beta barrels | X: OB-fold | H: Nucleic acid-binding proteins (From Topology) | T: Nucleic acid-binding proteins | F: PF00164 | ECOD (1.6) |
G [auth L6] | PF01092 | e7mqaL61 | A: beta barrels | X: Ribosomal protein L25-like | H: Ribosomal protein L25-like (From Topology) | T: Ribosomal protein L25-like | F: PF01092 | ECOD (1.6) |
Protein Family Annotation Pfam Database Homepage
Chains | Accession | Name | Description | Comments | Source |
---|---|---|---|---|---|
E [auth L4] | PF00900 | Ribosomal family S4e (Ribosomal_S4e) | Ribosomal family S4e | - | Family |
E [auth L4] | PF16121 | 40S ribosomal protein S4 C-terminus (40S_S4_C) | 40S ribosomal protein S4 C-terminus | - | Family |
E [auth L4] | PF08071 | RS4NT (NUC023) domain (RS4NT) | RS4NT (NUC023) domain | This is the N-terminal domain of Ribosomal S4 / S4e proteins. This domain is associated with S4 and KOW domains [1]. | Domain |
E [auth L4] | PF00467 | KOW motif (KOW) | KOW motif | - | Family |
H [auth L7] | PF01251 | Ribosomal protein S7e (Ribosomal_S7e) | Ribosomal protein S7e | - | Family |
I [auth L8] | PF01201 | Ribosomal protein S8e (Ribosomal_S8e) | Ribosomal protein S8e | - | Family |
J [auth L9] | PF00163 | Ribosomal protein S4/S9 N-terminal domain (Ribosomal_S4) | Ribosomal protein S4/S9 N-terminal domain | - | Family |
J [auth L9] | PF01479 | S4 domain (S4) | S4 domain | The S4 domain is a small domain consisting of 60-65 amino acid residues that was detected in the bacterial ribosomal protein S4, eukaryotic ribosomal S9, two families of pseudouridine synthases, a novel family of predicted RNA methylases, a yeast pro ... | Domain |
K [auth LA] | PF01248 | Ribosomal protein L7Ae/L30e/S12e/Gadd45 family (Ribosomal_L7Ae) | Ribosomal protein L7Ae/L30e/S12e/Gadd45 family | This family includes: Ribosomal L7A from metazoa, Ribosomal L8-A and L8-B from fungi, 30S ribosomal protein HS6 from archaebacteria, 40S ribosomal protein S12 from eukaryotes, Ribosomal protein L30 from eukaryotes and archaebacteria. Gadd45 and MyD11 ... | Domain |
L [auth LC] | PF00380 | Ribosomal protein S9/S16 (Ribosomal_S9) | Ribosomal protein S9/S16 | - | Family |
M [auth LD] | PF00366 | Ribosomal protein S17 (Ribosomal_S17) | Ribosomal protein S17 | - | Domain |
M [auth LD] | PF16205 | Ribosomal_S17 N-terminal (Ribosomal_S17_N) | Ribosomal_S17 N-terminal | - | Family |
N [auth LF] | PF01282 | Ribosomal protein S24e (Ribosomal_S24e) | Ribosomal protein S24e | - | Family |
O [auth LG] | PF01200 | Ribosomal protein S28e (Ribosomal_S28e) | Ribosomal protein S28e | - | Family |
P [auth LH] | PF00400 | WD domain, G-beta repeat (WD40) | WD domain, G-beta repeat | - | Repeat |
R [auth LJ] | PF09384 | UTP15 C terminal (UTP15_C) | UTP15 C terminal | - | Family |
R [auth LJ] | PF00400 | WD domain, G-beta repeat (WD40) | WD domain, G-beta repeat | - | Repeat |
S [auth LK], T [auth LL] | PF04003 | Dip2/Utp12 Family (Utp12) | Dip2/Utp12 Family | - | Family |
S [auth LK], T [auth LL] | PF00400 | WD domain, G-beta repeat (WD40) | WD domain, G-beta repeat | - | Repeat |
U [auth LM] | PF12397 | U3 small nucleolar RNA-associated protein 10 (U3snoRNP10) | U3 small nucleolar RNA-associated protein 10 | - | Family |
V [auth LN] | PF00400 | WD domain, G-beta repeat (WD40) | WD domain, G-beta repeat | - | Repeat |
W [auth LO] | PF04003 | Dip2/Utp12 Family (Utp12) | Dip2/Utp12 Family | - | Family |
W [auth LO] | PF00400 | WD domain, G-beta repeat (WD40) | WD domain, G-beta repeat | - | Repeat |
Y [auth LQ] | PF12894 | Anaphase-promoting complex subunit 4 WD40 domain (ANAPC4_WD40) | Anaphase-promoting complex subunit 4 WD40 domain | - | Repeat |
Y [auth LQ] | PF04003 | Dip2/Utp12 Family (Utp12) | Dip2/Utp12 Family | - | Family |
Y [auth LQ] | PF00400 | WD domain, G-beta repeat (WD40) | WD domain, G-beta repeat | - | Repeat |
AA [auth LS] | PF00400 | WD domain, G-beta repeat (WD40) | WD domain, G-beta repeat | - | Repeat |
BA [auth LT] | PF04192 | Utp21 specific WD40 associated putative domain (Utp21) | Utp21 specific WD40 associated putative domain | Utp21 is a subunit of U3 snoRNP, which is essential for synthesis of 18S rRNA. | Domain |
BA [auth LT] | PF12894 | Anaphase-promoting complex subunit 4 WD40 domain (ANAPC4_WD40) | Anaphase-promoting complex subunit 4 WD40 domain | - | Repeat |
BA [auth LT] | PF00400 | WD domain, G-beta repeat (WD40) | WD domain, G-beta repeat | - | Repeat |
CA [auth LU] | PF08662 | Eukaryotic translation initiation factor eIF2A (eIF2A) | Eukaryotic translation initiation factor eIF2A | - | Repeat |
CA [auth LU] | PF04158 | Sof1-like domain (Sof1) | Sof1-like domain | - | Family |
CA [auth LU] | PF00400 | WD domain, G-beta repeat (WD40) | WD domain, G-beta repeat | - | Repeat |
GA [auth NA] | PF04006 | Mpp10 protein (Mpp10) | Mpp10 protein | - | Family |
IA [auth ND] | PF08157 | NUC129 domain (NUC129) | NUC129 domain | This C terminal domain is found in a novel family of hypothetical nucleolar proteins [1]. | Domain |
JA [auth NF] | PF08069 | Ribosomal S13/S15 N-terminal domain (Ribosomal_S13_N) | Ribosomal S13/S15 N-terminal domain | This domain is found at the N-terminus of ribosomal S13 and S15 proteins. This domain is also identified as NUC021 [1]. | Domain |
JA [auth NF] | PF00312 | Ribosomal protein S15 (Ribosomal_S15) | Ribosomal protein S15 | - | Domain |
LA [auth NH] | PF03813 | Nrap protein domain 1 (Nrap) | Nrap protein domain 1 | Members of this family are nucleolar RNA-associated proteins (Nrap) which are highly conserved from yeast (Saccharomyces cerevisiae) to human. In the mouse, Nrap is ubiquitously expressed and is specifically localised in the nucleolus [1]. Nrap is a ... | Domain |
LA [auth NH] | PF17403 | Nrap protein PAP/OAS-like domain (Nrap_D2) | Nrap protein PAP/OAS-like domain | Members of this family are nucleolar RNA-associated proteins (Nrap) which are highly conserved from yeast (Saccharomyces cerevisiae) to human. In the mouse, Nrap is ubiquitously expressed and is specifically localised in the nucleolus [1]. Nrap is a ... | Domain |
LA [auth NH] | PF17406 | Nrap protein PAP/OAS1-like domain 5 (Nrap_D5) | Nrap protein PAP/OAS1-like domain 5 | Members of this family are nucleolar RNA-associated proteins (Nrap) which are highly conserved from yeast (Saccharomyces cerevisiae) to human. In the mouse, Nrap is ubiquitously expressed and is specifically localised in the nucleolus [1]. Nrap is a ... | Domain |
LA [auth NH] | PF17407 | Nrap protein domain 6 (Nrap_D6) | Nrap protein domain 6 | Members of this family are nucleolar RNA-associated proteins (Nrap) which are highly conserved from yeast (Saccharomyces cerevisiae) to human. In the mouse, Nrap is ubiquitously expressed and is specifically localised in the nucleolus [1]. Nrap is a ... | Domain |
LA [auth NH] | PF17404 | Nrap protein domain 3 (Nrap_D3) | Nrap protein domain 3 | Members of this family are nucleolar RNA-associated proteins (Nrap) which are highly conserved from yeast (Saccharomyces cerevisiae) to human. In the mouse, Nrap is ubiquitously expressed and is specifically localised in the nucleolus [1]. Nrap is a ... | Domain |
LA [auth NH] | PF17405 | Nrap protein nucleotidyltransferase domain 4 (Nrap_D4) | Nrap protein nucleotidyltransferase domain 4 | Members of this family are nucleolar RNA-associated proteins (Nrap) which are highly conserved from yeast (Saccharomyces cerevisiae) to human. In the mouse, Nrap is ubiquitously expressed and is specifically localised in the nucleolus [1]. Nrap is a ... | Domain |
MA [auth NI] | PF17799 | Rrp7 RRM-like N-terminal domain (RRM_Rrp7) | Rrp7 RRM-like N-terminal domain | This domain corresponds to the N-terminal RNA-binding domain found in the Rrp7 protein. It has an RRM-like fold with a circular permutation [1]. | Domain |
MA [auth NI] | PF12923 | Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain (RRP7) | Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain | RRP7 is an essential protein in yeast that is involved in pre-rRNA processing and ribosome assembly [1]. It is speculated to be required for correct assembly of rpS27 into the pre-ribosomal particle [1-2]. | Domain |
NA [auth NL] | PF00398 | Ribosomal RNA adenine dimethylase (RrnaAD) | Ribosomal RNA adenine dimethylase | - | Domain |
OA [auth NM] | PF01015 | Ribosomal S3Ae family (Ribosomal_S3Ae) | Ribosomal S3Ae family | - | Family |
QA [auth NP] | PF01090 | Ribosomal protein S19e (Ribosomal_S19e) | Ribosomal protein S19e | - | Family |
TA [auth NS] | PF04408 | Helicase associated domain (HA2), winged-helix (HA2_N) | Helicase associated domain (HA2), winged-helix | The helicase associated domain (HA2) has an all alpha-helical fold and consists of a N-terminal winged-helix (WH) domain and a C-terminal degenerate helical-bundle domain, referred to as the ratchet-like domain [1,2,3]. These domains collaborate wit ... | Domain |
TA [auth NS] | PF07717 | Oligonucleotide/oligosaccharide-binding (OB)-fold (OB_NTP_bind) | Oligonucleotide/oligosaccharide-binding (OB)-fold | This family is found towards the C-terminus of the DEAD-box helicases (Pfam:PF00270). In these helicases it is apparently always found in association with Pfam:PF04408. There do seem to be a couple of instances where it occurs by itself - e.g. Swiss: ... | Domain |
TA [auth NS] | PF00270 | DEAD/DEAH box helicase (DEAD) | DEAD/DEAH box helicase | Members of this family include the DEAD and DEAH box helicases. Helicases are involved in unwinding nucleic acids. The DEAD box helicases are involved in various aspects of RNA metabolism, including nuclear transcription, pre mRNA splicing, ribosome ... | Domain |
TA [auth NS] | PF21010 | Helicase associated domain (HA2), ratchet-like (HA2_C) | Helicase associated domain (HA2), ratchet-like | The helicase associated domain (HA2) has an all alpha-helical fold and consists of a N-terminal winged-helix (WH) domain (Pfam:PF04408) and a C-terminal degenerate helical-bundle domain, referred to as the ratchet-like domain [1,2,3]. These domains c ... | Domain |
VA [auth NU] | PF00833 | Ribosomal S17 (Ribosomal_S17e) | Ribosomal S17 | - | Family |
YA [auth SB] | PF08156 | NOP5NT (NUC127) domain (NOP5NT) | NOP5NT (NUC127) domain | This N terminal domain is found in RNA-binding proteins of the NOP5 family [1]. | Domain |
YA [auth SB] | PF01798 | snoRNA binding domain, fibrillarin (Nop) | snoRNA binding domain, fibrillarin | - | Family |
AB [auth SD], ZA [auth SC] | PF01269 | Fibrillarin (Fibrillarin) | Fibrillarin | - | Domain |
BB [auth SE], CB [auth SF] | PF01248 | Ribosomal protein L7Ae/L30e/S12e/Gadd45 family (Ribosomal_L7Ae) | Ribosomal protein L7Ae/L30e/S12e/Gadd45 family | This family includes: Ribosomal L7A from metazoa, Ribosomal L8-A and L8-B from fungi, 30S ribosomal protein HS6 from archaebacteria, 40S ribosomal protein S12 from eukaryotes, Ribosomal protein L30 from eukaryotes and archaebacteria. Gadd45 and MyD11 ... | Domain |
DB [auth SG] | PF00400 | WD domain, G-beta repeat (WD40) | WD domain, G-beta repeat | - | Repeat |
EB [auth SH] | PF05189 | RNA 3'-terminal phosphate cyclase (RTC), insert domain (RTC_insert) | RNA 3'-terminal phosphate cyclase (RTC), insert domain | RNA cyclases are a family of RNA-modifying enzymes that are conserved in all cellular organisms. They catalyse the ATP-dependent conversion of the 3'-phosphate to the 2',3'-cyclic phosphodiester at the end of RNA, in a reaction involving formation o ... | Domain |
EB [auth SH] | PF01137 | RNA 3'-terminal phosphate cyclase (RTC) | RNA 3'-terminal phosphate cyclase | RNA cyclases are a family of RNA-modifying enzymes that are conserved in all cellular organisms. They catalyse the ATP-dependent conversion of the 3'-phosphate to the 2',3'-cyclic phosphodiester at the end of RNA, in a reaction involving formation o ... | Domain |
FB [auth SI] | PF08142 | AARP2CN (NUC121) domain (AARP2CN) | AARP2CN (NUC121) domain | This domain is the central domain of AARP2. It is weakly similar to the GTP-binding domain of elongation factor TU [1]. | Domain |
IB [auth SL] | PF04900 | Fcf1 (Fcf1) | Fcf1 | - | Family |
JB [auth SM] | PF04427 | Brix domain (Brix) | Brix domain | - | Domain |
KB [auth SP] | PF20416 | U3 small nucleolar RNA-associated protein 20, C-terminal (UTP20_C) | U3 small nucleolar RNA-associated protein 20, C-terminal | This domain is found towards the C-terminal the U3 small nucleolar RNA-associated protein 20 (UTP20) from yeast and its human homologue, also known as DRIM (Down-Regulated In Metastasis). DRIM is differentially expressed in metastatic and non-metasta ... | Domain |
KB [auth SP] | PF07539 | U3 small nucleolar RNA-associated protein 20, N-terminal (UTP20_N) | U3 small nucleolar RNA-associated protein 20, N-terminal | This domain is found towards the N-terminal of eukaryotic proteins including U3 small nucleolar RNA-associated protein 20 (UTP20) from yeast and the homologue from human, also known as DRIM (Down-Regulated In Metastasis) (Swiss:O75691), which is diff ... | Domain |
LB [auth SQ] | PF08698 | Fcf2 pre-rRNA processing (Fcf2) | Fcf2 pre-rRNA processing | - | Family |
SB [auth SY] | PF03998 | Utp11 protein (Utp11) | Utp11 protein | - | Family |
X [auth LP] | PF08640 | U3 small nucleolar RNA-associated protein 6 (U3_assoc_6) | U3 small nucleolar RNA-associated protein 6 | - | Family |
Z [auth LR] | PF00400 | WD domain, G-beta repeat (WD40) | WD domain, G-beta repeat | - | Repeat |
Z [auth LR] | PF08625 | Utp13 specific WD40 associated domain (Utp13) | Utp13 specific WD40 associated domain | Utp13 is a component of the five protein Pwp2 complex that forms part of a stable particle subunit independent of the U3 small nucleolar ribonucleoprotein that is essential for the initial assembly steps of the 90S pre-ribosome [1]. Pwp2 is capable o ... | Domain |
DA [auth LW] | PF08149 | BING4CT (NUC141) domain (BING4CT) | BING4CT (NUC141) domain | This C terminal domain is found in the BING4 family of nucleolar WD40 repeat proteins [1]. | Domain |
DA [auth LW] | PF00400 | WD domain, G-beta repeat (WD40) | WD domain, G-beta repeat | - | Repeat |
FA [auth LZ] | PF00163 | Ribosomal protein S4/S9 N-terminal domain (Ribosomal_S4) | Ribosomal protein S4/S9 N-terminal domain | - | Family |
FA [auth LZ] | PF01479 | S4 domain (S4) | S4 domain | The S4 domain is a small domain consisting of 60-65 amino acid residues that was detected in the bacterial ribosomal protein S4, eukaryotic ribosomal S9, two families of pseudouridine synthases, a novel family of predicted RNA methylases, a yeast pro ... | Domain |
KA [auth NG] | PF00411 | Ribosomal protein S11 (Ribosomal_S11) | Ribosomal protein S11 | - | Family |
PA [auth NO] | PF00410 | Ribosomal protein S8 (Ribosomal_S8) | Ribosomal protein S8 | - | Domain |
RA [auth NQ] | PF01667 | Ribosomal protein S27 (Ribosomal_S27e) | Ribosomal protein S27 | - | Family |
UA [auth NT] | PF01599 | Ribosomal protein S27a (Ribosomal_S27) | Ribosomal protein S27a | This family of ribosomal proteins consists mainly of the 40S ribosomal protein S27a which is synthesised as a C-terminal extension of ubiquitin (CEP). The S27a domain compromises the C-terminal half of the protein. The synthesis of ribosomal proteins ... | Domain |
XA [auth SA] | PF08156 | NOP5NT (NUC127) domain (NOP5NT) | NOP5NT (NUC127) domain | This N terminal domain is found in RNA-binding proteins of the NOP5 family [1]. | Domain |
XA [auth SA] | PF01798 | snoRNA binding domain, fibrillarin (Nop) | snoRNA binding domain, fibrillarin | - | Family |
GB [auth SJ], HB [auth SK] | PF03587 | EMG1/NEP1 methyltransferase (EMG1) | EMG1/NEP1 methyltransferase | - | Family |
F [auth L5] | PF00177 | Ribosomal protein S7p/S5e (Ribosomal_S7) | Ribosomal protein S7p/S5e | This family contains ribosomal protein S7 from prokaryotes and S5 from eukaryotes. | Domain |
MB [auth SR] | PF00164 | Ribosomal protein S12/S23 (Ribosom_S12_S23) | Ribosomal protein S12/S23 | - | Family |
NB [auth SS] | PF04615 | Utp14 protein (Utp14) | Utp14 protein | - | Family |
G [auth L6] | PF01092 | Ribosomal protein S6e (Ribosomal_S6e) | Ribosomal protein S6e | - | Family |