Annotations: 7KTR

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
H	SCOP2B Superfamily	Core histone-like	8053233	3001387	SCOP2B (2022-06-29)
G	SCOP2B Superfamily	Core histone-like	8042408	3001387	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
H	PF03540	e7ktrH1	A: alpha arrays	X: Histone-like	H: Histone-related	T: Histone	F: PF03540	ECOD (1.6)
B	PF00400	e7ktrB1	A: beta duplicates or obligate multimers	X: beta-propeller-like	H: beta-propeller	T: 8-bladed	F: PF00400	ECOD (1.6)
B	F_UNCLASSIFIED	e7ktrB3	A: alpha duplicates or obligate multimers	X: Lis-homology dimerization domain (From Topology)	H: Lis-homology dimerization domain (From Topology)	T: Lis-homology dimerization domain	F: F_UNCLASSIFIED	ECOD (1.6)
B	PF04494	e7ktrB2	A: alpha superhelices	X: Taf5 N-terminal domain-like (From Topology)	H: Taf5 N-terminal domain-like (From Topology)	T: Taf5 N-terminal domain-like	F: PF04494	ECOD (1.6)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
H	PF03540	Transcription initiation factor TFIID 23-30kDa subunit (TFIID_30kDa)	Transcription initiation factor TFIID 23-30kDa subunit	-	Family
A	PF20175	Tra1 HEAT repeat central region (Tra1_central)	Tra1 HEAT repeat central region	-	Repeat
A	PF20206	Tra1 HEAT repeat ring region (Tra1_ring)	Tra1 HEAT repeat ring region	-	Repeat
A	PF00454	Phosphatidylinositol 3- and 4-kinase (PI3_PI4_kinase)	Phosphatidylinositol 3- and 4-kinase	-	Family
A	PF02259	FAT domain (FAT)	FAT domain	-	Repeat
J	PF12767	Transcriptional regulator of RNA polII, SAGA, subunit (SAGA-Tad1)	Transcriptional regulator of RNA polII, SAGA, subunit	-	Family
B	PF04494	WD40 associated region in TFIID subunit, NTD2 domain (TFIID_NTD2)	WD40 associated region in TFIID subunit, NTD2 domain	-	Family
B	PF00400	WD domain, G-beta repeat (WD40)	WD domain, G-beta repeat	-	Repeat
C	PF12090	Spt20, SEP domain (Spt20_SEP)	Spt20, SEP domain	This is the SEP domain found in Spt20 proteins from both human and yeast. The Spt20 protein is part of the SAGA complex which is a large complex mediating histone deacetylation. Yeast Spt20 has been shown to play a role in structural integrity of the ...	This is the SEP domain found in Spt20 proteins from both human and yeast. The Spt20 protein is part of the SAGA complex which is a large complex mediating histone deacetylation. Yeast Spt20 has been shown to play a role in structural integrity of the SAGA complex as as no intact SAGA could be purified in spt20 deletion strains [1]. Spt20 is indispensable under endoplasmic reticulum (ER) stress conditions, being involved in the regulation of stress-responsive genes transcription. This domain interacts with LisH motif helices of Taf5 [2,3].	Domain
D	PF07524	Bromodomain associated (Bromo_TP)	Bromodomain associated	This domain is predicted to bind DNA [1] and is often found associated with Pfam:PF00439 and in transcription factors. It has a histone-like fold.	Domain
E	PF02291	Transcription initiation factor IID, 31kD subunit (TFIID-31kDa)	Transcription initiation factor IID, 31kD subunit	This family represents the N-terminus of the 31kD subunit (42kD in drosophila) of transcription initiation factor IID (TAFII31). TAFII31 binds to p53, and is an essential requirement for p53 mediated transcription activation.	Domain
F	PF02969	TATA box binding protein associated factor (TAF) (TAF)	TATA box binding protein associated factor (TAF)	TAF proteins adopt a histone-like fold.	Domain
G	PF03847	Transcription initiation factor TFIID subunit A (TFIID_20kDa)	Transcription initiation factor TFIID subunit A	-	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
H	Transcription initiation factor TFIID subunit 10	RNA polymerase binding protein binding binding enzyme binding protein-containing complex binding chromatin binding promoter-specific chromatin binding DNA binding organic cyclic compound binding nucleic acid binding general transcription initiation factor activity RNA polymerase II general transcription initiation factor activity transcription factor binding RNA polymerase II-specific DNA-binding transcription factor binding RNA polymerase binding protein binding binding enzyme binding protein-containing complex binding chromatin binding promoter-specific chromatin binding DNA binding organic cyclic compound binding nucleic acid binding general transcription initiation factor activity RNA polymerase II general transcription initiation factor activity transcription factor binding RNA polymerase II-specific DNA-binding transcription factor binding nuclear receptor binding DNA-binding transcription factor binding nuclear estrogen receptor binding identical protein binding	cellular biosynthetic process transcription preinitiation complex assembly RNA metabolic process cellular component organization cellular component biogenesis protein-DNA complex organization RNA biosynthetic process nucleobase-containing compound metabolic process DNA-templated transcription nucleic acid biosynthetic process cellular component assembly organic substance metabolic process transcription by RNA polymerase II protein-containing complex assembly organic substance biosynthetic process cellular biosynthetic process transcription preinitiation complex assembly RNA metabolic process cellular component organization cellular component biogenesis protein-DNA complex organization RNA biosynthetic process nucleobase-containing compound metabolic process DNA-templated transcription nucleic acid biosynthetic process cellular component assembly organic substance metabolic process transcription by RNA polymerase II protein-containing complex assembly organic substance biosynthetic process cellular component organization or biogenesis transcription initiation at RNA polymerase II promoter protein-containing complex organization cellular metabolic process protein-DNA complex assembly primary metabolic process nucleobase-containing compound biosynthetic process gene expression macromolecule biosynthetic process DNA-templated transcription initiation nucleic acid metabolic process organic cyclic compound metabolic process biosynthetic process organic cyclic compound biosynthetic process RNA polymerase II preinitiation complex assembly cellular process metabolic process macromolecule metabolic process developmental process extraembryonic membrane development allantois development anatomical structure development somitogenesis multicellular organismal process epithelium development chordate embryonic development segmentation anterior/posterior pattern specification pattern specification process embryo development tissue development regionalization multicellular organism development anatomical structure morphogenesis embryo development ending in birth or egg hatching somite development anatomical structure formation involved in morphogenesis apoptotic process cell death programmed cell death placenta development animal organ development in utero embryonic development embryonic placenta development embryonic organ development mesodermal cell differentiation cellular developmental process mesoderm morphogenesis lateral mesoderm development lateral mesoderm morphogenesis mesenchyme development cell differentiation lateral mesoderm formation animal organ morphogenesis mesoderm formation mesoderm development formation of primary germ layer mesenchyme morphogenesis embryonic morphogenesis lateral mesodermal cell differentiation gastrulation tissue morphogenesis regulation of cellular process positive regulation of macromolecule biosynthetic process regulation of primary metabolic process positive regulation of metabolic process regulation of DNA-templated transcription initiation regulation of RNA metabolic process positive regulation of macromolecule metabolic process regulation of nucleobase-containing compound metabolic process regulation of transcription by RNA polymerase II regulation of biological process positive regulation of nucleobase-containing compound metabolic process regulation of cellular metabolic process positive regulation of transcription by RNA polymerase II positive regulation of DNA-templated transcription initiation positive regulation of RNA metabolic process regulation of gene expression regulation of macromolecule biosynthetic process regulation of DNA-templated transcription regulation of metabolic process positive regulation of DNA-templated transcription positive regulation of biological process positive regulation of cellular metabolic process positive regulation of biosynthetic process positive regulation of cellular process regulation of RNA biosynthetic process regulation of biosynthetic process positive regulation of transcription initiation by RNA polymerase II biological regulation regulation of macromolecule metabolic process regulation of cellular biosynthetic process positive regulation of RNA biosynthetic process regulation of transcription initiation by RNA polymerase II positive regulation of cellular biosynthetic process limb development appendage development SAGA complex assembly gland development liver development epithelial cell differentiation hepaticobiliary system development hepatocyte differentiation system development mitotic cell cycle process cell cycle phase transition cell cycle G1/S transition of mitotic cell cycle cell cycle G1/S phase transition mitotic cell cycle mitotic cell cycle phase transition cell cycle process mRNA transcription by RNA polymerase II mRNA transcription mRNA metabolic process multicellular organism growth developmental growth growth cellular response to stimulus response to stimulus regulation of cellular response to stress cellular response to stress response to stress regulation of response to stress DNA repair DNA metabolic process regulation of DNA repair DNA damage response regulation of response to stimulus regulation of DNA metabolic process RNA processing RNA splicing regulation of RNA splicing chromatin organization chromatin remodeling	transcription preinitiation complex protein-containing complex protein-DNA complex RNA polymerase II transcription regulator complex membrane-bounded organelle RNA polymerase II, holoenzyme intracellular anatomical structure nucleus membrane-enclosed lumen nuclear protein-containing complex transcription regulator complex transferase complex intracellular organelle lumen intracellular organelle transcription preinitiation complex protein-containing complex protein-DNA complex RNA polymerase II transcription regulator complex membrane-bounded organelle RNA polymerase II, holoenzyme intracellular anatomical structure nucleus membrane-enclosed lumen nuclear protein-containing complex transcription regulator complex transferase complex intracellular organelle lumen intracellular organelle nucleoplasm catalytic complex intracellular membrane-bounded organelle cellular anatomical entity transferase complex, transferring phosphorus-containing groups nuclear DNA-directed RNA polymerase complex organelle lumen organelle RNA polymerase complex transcription factor TFIID complex DNA-directed RNA polymerase complex intracellular protein-containing complex nuclear lumen cytoplasm peptidase complex chromatin chromosome histone acetyltransferase complex acetyltransferase complex intracellular non-membrane-bounded organelle protein acetyltransferase complex SAGA-type complex SAGA complex non-membrane-bounded organelle transcription factor TFTC complex perinuclear region of cytoplasm male germ cell nucleus germ cell nucleus
I	Transcription initiation protein SPT3 homolog,Transcription initiation protein SPT3 homolog,Transcription initiation protein SPT3 homolog	protein heterodimerization activity protein binding binding protein dimerization activity transcription coactivator activity transcription regulator activity transcription coregulator activity protein-macromolecule adaptor activity molecular adaptor activity	regulation of cellular process cellular biosynthetic process RNA metabolic process regulation of primary metabolic process nucleobase-containing compound metabolic process RNA biosynthetic process nucleic acid biosynthetic process DNA-templated transcription regulation of RNA metabolic process organic substance metabolic process organic substance biosynthetic process regulation of nucleobase-containing compound metabolic process regulation of RNA biosynthetic process regulation of biosynthetic process regulation of cellular process cellular biosynthetic process RNA metabolic process regulation of primary metabolic process nucleobase-containing compound metabolic process RNA biosynthetic process nucleic acid biosynthetic process DNA-templated transcription regulation of RNA metabolic process organic substance metabolic process organic substance biosynthetic process regulation of nucleobase-containing compound metabolic process regulation of RNA biosynthetic process regulation of biosynthetic process regulation of biological process cellular metabolic process biological regulation primary metabolic process regulation of cellular metabolic process regulation of macromolecule metabolic process nucleobase-containing compound biosynthetic process gene expression macromolecule biosynthetic process nucleic acid metabolic process regulation of cellular biosynthetic process organic cyclic compound metabolic process regulation of gene expression biosynthetic process organic cyclic compound biosynthetic process metabolic process regulation of macromolecule biosynthetic process cellular process regulation of DNA-templated transcription macromolecule metabolic process regulation of metabolic process transcription preinitiation complex assembly cellular component organization cellular component biogenesis protein-DNA complex organization cellular component assembly transcription by RNA polymerase II protein-containing complex assembly cellular component organization or biogenesis transcription initiation at RNA polymerase II promoter protein-containing complex organization protein-DNA complex assembly DNA-templated transcription initiation RNA polymerase II preinitiation complex assembly positive regulation of macromolecule biosynthetic process positive regulation of metabolic process positive regulation of macromolecule metabolic process positive regulation of nucleobase-containing compound metabolic process positive regulation of RNA metabolic process positive regulation of DNA-templated transcription positive regulation of biological process positive regulation of cellular metabolic process positive regulation of biosynthetic process positive regulation of cellular process positive regulation of RNA biosynthetic process positive regulation of cellular biosynthetic process regulation of transcription by RNA polymerase II cellular response to stimulus response to stimulus regulation of cellular response to stress cellular response to stress response to stress regulation of response to stress DNA repair DNA metabolic process regulation of DNA repair DNA damage response regulation of response to stimulus regulation of DNA metabolic process RNA processing RNA splicing regulation of RNA splicing	protein-containing complex intracellular anatomical structure catalytic complex peptidase complex protein-DNA complex chromatin chromosome transferase complex cellular anatomical entity histone acetyltransferase complex acetyltransferase complex intracellular organelle organelle intracellular non-membrane-bounded organelle protein-containing complex intracellular anatomical structure catalytic complex peptidase complex protein-DNA complex chromatin chromosome transferase complex cellular anatomical entity histone acetyltransferase complex acetyltransferase complex intracellular organelle organelle intracellular non-membrane-bounded organelle protein acetyltransferase complex SAGA-type complex SAGA complex intracellular protein-containing complex non-membrane-bounded organelle RNA polymerase II transcription regulator complex membrane-bounded organelle transcription factor TFTC complex RNA polymerase II, holoenzyme nucleus membrane-enclosed lumen nuclear protein-containing complex transcription regulator complex intracellular organelle lumen nucleoplasm intracellular membrane-bounded organelle transferase complex, transferring phosphorus-containing groups nuclear DNA-directed RNA polymerase complex organelle lumen RNA polymerase complex DNA-directed RNA polymerase complex nuclear lumen transcription factor TFIID complex
A	Transformation/transcription domain-associated protein,Transformation/transcription domain-associated protein,Transformation/transcription domain-associated protein,Transformation/transcription domain-associated protein	transcription regulator activity transcription coregulator activity protein-macromolecule adaptor activity molecular adaptor activity	regulation of biological process regulation of cellular process regulation of apoptotic process biological regulation cellular process apoptotic process regulation of programmed cell death cell death programmed cell death cellular response to stimulus regulation of double-strand break repair response to stimulus regulation of cellular response to stress regulation of primary metabolic process regulation of biological process regulation of cellular process regulation of apoptotic process biological regulation cellular process apoptotic process regulation of programmed cell death cell death programmed cell death cellular response to stimulus regulation of double-strand break repair response to stimulus regulation of cellular response to stress regulation of primary metabolic process nucleobase-containing compound metabolic process organic substance metabolic process cellular response to stress response to stress regulation of response to stress regulation of nucleobase-containing compound metabolic process DNA repair double-strand break repair primary metabolic process DNA metabolic process regulation of macromolecule metabolic process nucleic acid metabolic process regulation of DNA repair organic cyclic compound metabolic process DNA damage response regulation of response to stimulus metabolic process macromolecule metabolic process regulation of metabolic process regulation of DNA metabolic process regulation of DNA recombination positive regulation of biological process positive regulation of double-strand break repair via homologous recombination positive regulation of response to stimulus positive regulation of metabolic process positive regulation of DNA repair recombinational repair positive regulation of macromolecule metabolic process double-strand break repair via homologous recombination positive regulation of cellular process positive regulation of DNA recombination positive regulation of nucleobase-containing compound metabolic process DNA recombination positive regulation of double-strand break repair regulation of double-strand break repair via homologous recombination positive regulation of DNA metabolic process cellular biosynthetic process RNA metabolic process RNA biosynthetic process nucleic acid biosynthetic process DNA-templated transcription regulation of RNA metabolic process organic substance biosynthetic process regulation of RNA biosynthetic process regulation of biosynthetic process cellular metabolic process regulation of cellular metabolic process nucleobase-containing compound biosynthetic process gene expression macromolecule biosynthetic process regulation of cellular biosynthetic process regulation of gene expression biosynthetic process organic cyclic compound biosynthetic process regulation of macromolecule biosynthetic process regulation of DNA-templated transcription positive regulation of macromolecule biosynthetic process positive regulation of RNA metabolic process positive regulation of DNA-templated transcription positive regulation of cellular metabolic process positive regulation of biosynthetic process positive regulation of RNA biosynthetic process positive regulation of cellular biosynthetic process transcription by RNA polymerase II regulation of transcription by RNA polymerase II cell cycle regulation of cell cycle RNA processing RNA splicing regulation of RNA splicing protein-DNA complex organization cellular component organization protein-containing complex organization chromatin organization cellular component organization or biogenesis	protein-containing complex intracellular anatomical structure catalytic complex protein-DNA complex NuA4 histone acetyltransferase complex chromatin chromosome transferase complex cellular anatomical entity H4/H2A histone acetyltransferase complex histone acetyltransferase complex acetyltransferase complex H4 histone acetyltransferase complex intracellular organelle protein-containing complex intracellular anatomical structure catalytic complex protein-DNA complex NuA4 histone acetyltransferase complex chromatin chromosome transferase complex cellular anatomical entity H4/H2A histone acetyltransferase complex histone acetyltransferase complex acetyltransferase complex H4 histone acetyltransferase complex intracellular organelle organelle intracellular non-membrane-bounded organelle protein acetyltransferase complex intracellular protein-containing complex non-membrane-bounded organelle nucleosome membrane-bounded organelle nucleus membrane-enclosed lumen intracellular membrane-bounded organelle intracellular organelle lumen nucleoplasm organelle lumen nuclear lumen peptidase complex SAGA-type complex SAGA complex RNA polymerase II transcription regulator complex transcription factor TFTC complex RNA polymerase II, holoenzyme nuclear protein-containing complex transcription regulator complex transferase complex, transferring phosphorus-containing groups nuclear DNA-directed RNA polymerase complex RNA polymerase complex DNA-directed RNA polymerase complex Golgi apparatus cytoplasm endomembrane system ATPase complex nuclear chromosome histone deacetylase complex SWI/SNF superfamily-type complex INO80-type complex Swr1 complex
J	Transcriptional adapter 1	transcription coactivator activity transcription regulator activity transcription coregulator activity protein-macromolecule adaptor activity molecular adaptor activity	regulation of cellular process cellular biosynthetic process RNA metabolic process regulation of primary metabolic process RNA biosynthetic process nucleobase-containing compound metabolic process DNA-templated transcription nucleic acid biosynthetic process regulation of RNA metabolic process transcription by RNA polymerase II organic substance metabolic process organic substance biosynthetic process regulation of nucleobase-containing compound metabolic process regulation of RNA biosynthetic process regulation of cellular process cellular biosynthetic process RNA metabolic process regulation of primary metabolic process RNA biosynthetic process nucleobase-containing compound metabolic process DNA-templated transcription nucleic acid biosynthetic process regulation of RNA metabolic process transcription by RNA polymerase II organic substance metabolic process organic substance biosynthetic process regulation of nucleobase-containing compound metabolic process regulation of RNA biosynthetic process regulation of transcription by RNA polymerase II regulation of biosynthetic process regulation of biological process cellular metabolic process biological regulation primary metabolic process regulation of cellular metabolic process regulation of macromolecule metabolic process nucleobase-containing compound biosynthetic process gene expression macromolecule biosynthetic process nucleic acid metabolic process regulation of cellular biosynthetic process organic cyclic compound metabolic process regulation of gene expression biosynthetic process organic cyclic compound biosynthetic process metabolic process cellular process regulation of macromolecule biosynthetic process macromolecule metabolic process regulation of DNA-templated transcription regulation of metabolic process cellular response to stimulus response to stimulus regulation of cellular response to stress cellular response to stress response to stress regulation of response to stress DNA repair DNA metabolic process regulation of DNA repair DNA damage response regulation of response to stimulus regulation of DNA metabolic process RNA processing RNA splicing regulation of RNA splicing positive regulation of macromolecule biosynthetic process positive regulation of metabolic process positive regulation of macromolecule metabolic process positive regulation of nucleobase-containing compound metabolic process positive regulation of RNA metabolic process positive regulation of DNA-templated transcription positive regulation of biological process positive regulation of cellular metabolic process positive regulation of biosynthetic process positive regulation of cellular process positive regulation of RNA biosynthetic process positive regulation of cellular biosynthetic process	intracellular anatomical structure cytoplasm cellular anatomical entity cytosol anchoring junction cell junction focal adhesion cell-substrate junction protein-containing complex catalytic complex peptidase complex protein-DNA complex chromatin chromosome intracellular anatomical structure cytoplasm cellular anatomical entity cytosol anchoring junction cell junction focal adhesion cell-substrate junction protein-containing complex catalytic complex peptidase complex protein-DNA complex chromatin chromosome transferase complex histone acetyltransferase complex acetyltransferase complex intracellular organelle organelle intracellular non-membrane-bounded organelle protein acetyltransferase complex SAGA-type complex SAGA complex intracellular protein-containing complex non-membrane-bounded organelle membrane-bounded organelle nucleus membrane-enclosed lumen intracellular membrane-bounded organelle intracellular organelle lumen nucleoplasm organelle lumen nuclear lumen
K [auth N]	Ataxin-7	-	cellular component organization organelle organization microtubule cytoskeleton organization cellular process microtubule-based process cellular component organization or biogenesis cytoskeleton organization regulation of cellular process positive regulation of macromolecule biosynthetic process regulation of primary metabolic process nucleobase-containing compound metabolic process positive regulation of metabolic process DNA-templated transcription regulation of RNA metabolic process cellular component organization organelle organization microtubule cytoskeleton organization cellular process microtubule-based process cellular component organization or biogenesis cytoskeleton organization regulation of cellular process positive regulation of macromolecule biosynthetic process regulation of primary metabolic process nucleobase-containing compound metabolic process positive regulation of metabolic process DNA-templated transcription regulation of RNA metabolic process organic substance biosynthetic process positive regulation of macromolecule metabolic process regulation of nucleobase-containing compound metabolic process regulation of biological process positive regulation of nucleobase-containing compound metabolic process cellular metabolic process primary metabolic process regulation of cellular metabolic process positive regulation of RNA metabolic process organic cyclic compound metabolic process regulation of gene expression biosynthetic process organic cyclic compound biosynthetic process metabolic process regulation of macromolecule biosynthetic process macromolecule metabolic process regulation of DNA-templated transcription regulation of metabolic process positive regulation of DNA-templated transcription cellular biosynthetic process positive regulation of biological process RNA metabolic process positive regulation of cellular metabolic process RNA biosynthetic process nucleic acid biosynthetic process organic substance metabolic process positive regulation of biosynthetic process positive regulation of cellular process regulation of RNA biosynthetic process regulation of biosynthetic process biological regulation regulation of macromolecule metabolic process nucleobase-containing compound biosynthetic process gene expression macromolecule biosynthetic process nucleic acid metabolic process regulation of cellular biosynthetic process positive regulation of RNA biosynthetic process positive regulation of cellular biosynthetic process multicellular organismal process sensory perception of light stimulus system process sensory perception nervous system process visual perception transcription by RNA polymerase II regulation of transcription by RNA polymerase II nucleus organization cellular response to stimulus response to stimulus regulation of cellular response to stress cellular response to stress response to stress regulation of response to stress DNA repair DNA metabolic process regulation of DNA repair DNA damage response regulation of response to stimulus regulation of DNA metabolic process RNA processing RNA splicing regulation of RNA splicing regulation of cytoskeleton organization regulation of microtubule polymerization or depolymerization regulation of cellular component organization negative regulation of microtubule depolymerization negative regulation of biological process protein-containing complex disassembly regulation of protein-containing complex disassembly microtubule polymerization or depolymerization regulation of microtubule depolymerization negative regulation of protein-containing complex disassembly negative regulation of cellular process negative regulation of supramolecular fiber organization cellular component disassembly negative regulation of cellular component organization negative regulation of microtubule polymerization or depolymerization protein-containing complex organization regulation of protein depolymerization negative regulation of cytoskeleton organization regulation of microtubule-based process regulation of organelle organization negative regulation of protein depolymerization negative regulation of organelle organization microtubule depolymerization regulation of supramolecular fiber organization supramolecular fiber organization protein depolymerization regulation of microtubule cytoskeleton organization	membrane-bounded organelle intracellular anatomical structure nucleus membrane-enclosed lumen intracellular membrane-bounded organelle cellular anatomical entity intracellular organelle lumen intracellular organelle organelle lumen organelle nuclear periphery nuclear lumen nuclear matrix nucleolus membrane-bounded organelle intracellular anatomical structure nucleus membrane-enclosed lumen intracellular membrane-bounded organelle cellular anatomical entity intracellular organelle lumen intracellular organelle organelle lumen organelle nuclear periphery nuclear lumen nuclear matrix nucleolus intracellular non-membrane-bounded organelle non-membrane-bounded organelle protein-containing complex catalytic complex peptidase complex protein-DNA complex chromatin chromosome transferase complex histone acetyltransferase complex acetyltransferase complex protein acetyltransferase complex SAGA-type complex SAGA complex intracellular protein-containing complex RNA polymerase II transcription regulator complex transcription factor TFTC complex RNA polymerase II, holoenzyme nuclear protein-containing complex transcription regulator complex nucleoplasm transferase complex, transferring phosphorus-containing groups nuclear DNA-directed RNA polymerase complex RNA polymerase complex DNA-directed RNA polymerase complex cytoplasm cytosol cytoskeleton microtubule cytoskeleton
B	TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 5L	transcription coactivator activity transcription regulator activity transcription coregulator activity protein-macromolecule adaptor activity molecular adaptor activity	regulation of cellular process cellular biosynthetic process RNA metabolic process regulation of primary metabolic process nucleobase-containing compound metabolic process RNA biosynthetic process nucleic acid biosynthetic process DNA-templated transcription regulation of RNA metabolic process organic substance metabolic process organic substance biosynthetic process regulation of nucleobase-containing compound metabolic process regulation of RNA biosynthetic process regulation of biosynthetic process regulation of cellular process cellular biosynthetic process RNA metabolic process regulation of primary metabolic process nucleobase-containing compound metabolic process RNA biosynthetic process nucleic acid biosynthetic process DNA-templated transcription regulation of RNA metabolic process organic substance metabolic process organic substance biosynthetic process regulation of nucleobase-containing compound metabolic process regulation of RNA biosynthetic process regulation of biosynthetic process regulation of biological process cellular metabolic process biological regulation primary metabolic process regulation of cellular metabolic process regulation of macromolecule metabolic process nucleobase-containing compound biosynthetic process gene expression macromolecule biosynthetic process nucleic acid metabolic process regulation of cellular biosynthetic process organic cyclic compound metabolic process regulation of gene expression biosynthetic process organic cyclic compound biosynthetic process metabolic process regulation of macromolecule biosynthetic process cellular process regulation of DNA-templated transcription macromolecule metabolic process regulation of metabolic process transcription by RNA polymerase II positive regulation of macromolecule biosynthetic process positive regulation of metabolic process positive regulation of macromolecule metabolic process positive regulation of nucleobase-containing compound metabolic process positive regulation of RNA metabolic process positive regulation of DNA-templated transcription positive regulation of biological process positive regulation of cellular metabolic process positive regulation of biosynthetic process positive regulation of cellular process positive regulation of RNA biosynthetic process positive regulation of cellular biosynthetic process regulation of transcription by RNA polymerase II cellular response to stimulus response to stimulus regulation of cellular response to stress cellular response to stress response to stress regulation of response to stress DNA repair DNA metabolic process regulation of DNA repair DNA damage response regulation of response to stimulus regulation of DNA metabolic process RNA processing RNA splicing regulation of RNA splicing developmental process regulation of somatic stem cell population maintenance multicellular organismal process regulation of developmental process regulation of stem cell population maintenance stem cell population maintenance somatic stem cell population maintenance regulation of multicellular organismal process maintenance of cell number	protein-containing complex intracellular anatomical structure catalytic complex protein-DNA complex chromatin chromosome transferase complex cellular anatomical entity histone acetyltransferase complex acetyltransferase complex intracellular organelle organelle intracellular non-membrane-bounded organelle protein acetyltransferase complex protein-containing complex intracellular anatomical structure catalytic complex protein-DNA complex chromatin chromosome transferase complex cellular anatomical entity histone acetyltransferase complex acetyltransferase complex intracellular organelle organelle intracellular non-membrane-bounded organelle protein acetyltransferase complex intracellular protein-containing complex non-membrane-bounded organelle cytoplasmic ribonucleoprotein granule cytoplasm supramolecular complex ribonucleoprotein granule peptidase complex SAGA-type complex SAGA complex RNA polymerase II transcription regulator complex membrane-bounded organelle transcription factor TFTC complex RNA polymerase II, holoenzyme nucleus membrane-enclosed lumen nuclear protein-containing complex transcription regulator complex intracellular organelle lumen nucleoplasm intracellular membrane-bounded organelle transferase complex, transferring phosphorus-containing groups nuclear DNA-directed RNA polymerase complex organelle lumen RNA polymerase complex DNA-directed RNA polymerase complex nuclear lumen nuclear speck nuclear body
C	Isoform 3 of Transcription factor SPT20 homolog	transcription regulator activity transcription coregulator activity protein-macromolecule adaptor activity molecular adaptor activity	developmental process multicellular organism development multicellular organismal process anatomical structure morphogenesis embryonic morphogenesis anatomical structure development embryo development gastrulation regulation of cellular process cellular biosynthetic process RNA metabolic process regulation of primary metabolic process RNA biosynthetic process nucleobase-containing compound metabolic process developmental process multicellular organism development multicellular organismal process anatomical structure morphogenesis embryonic morphogenesis anatomical structure development embryo development gastrulation regulation of cellular process cellular biosynthetic process RNA metabolic process regulation of primary metabolic process RNA biosynthetic process nucleobase-containing compound metabolic process DNA-templated transcription nucleic acid biosynthetic process regulation of RNA metabolic process transcription by RNA polymerase II organic substance metabolic process organic substance biosynthetic process regulation of nucleobase-containing compound metabolic process regulation of RNA biosynthetic process regulation of transcription by RNA polymerase II regulation of biosynthetic process regulation of biological process cellular metabolic process biological regulation primary metabolic process regulation of cellular metabolic process regulation of macromolecule metabolic process nucleobase-containing compound biosynthetic process gene expression macromolecule biosynthetic process nucleic acid metabolic process regulation of cellular biosynthetic process organic cyclic compound metabolic process regulation of gene expression biosynthetic process organic cyclic compound biosynthetic process metabolic process cellular process regulation of macromolecule biosynthetic process macromolecule metabolic process regulation of DNA-templated transcription regulation of metabolic process cellular response to stimulus response to stimulus regulation of cellular response to stress cellular response to stress response to stress regulation of response to stress DNA repair DNA metabolic process regulation of DNA repair DNA damage response regulation of response to stimulus regulation of DNA metabolic process RNA processing RNA splicing regulation of RNA splicing positive regulation of macromolecule biosynthetic process positive regulation of metabolic process positive regulation of macromolecule metabolic process positive regulation of nucleobase-containing compound metabolic process positive regulation of RNA metabolic process positive regulation of DNA-templated transcription positive regulation of biological process positive regulation of cellular metabolic process positive regulation of biosynthetic process positive regulation of cellular process positive regulation of RNA biosynthetic process positive regulation of cellular biosynthetic process cellular catabolic process catabolic process autophagy process utilizing autophagic mechanism	protein-containing complex intracellular anatomical structure catalytic complex peptidase complex protein-DNA complex chromatin chromosome transferase complex cellular anatomical entity histone acetyltransferase complex acetyltransferase complex intracellular organelle organelle intracellular non-membrane-bounded organelle protein-containing complex intracellular anatomical structure catalytic complex peptidase complex protein-DNA complex chromatin chromosome transferase complex cellular anatomical entity histone acetyltransferase complex acetyltransferase complex intracellular organelle organelle intracellular non-membrane-bounded organelle protein acetyltransferase complex SAGA-type complex SAGA complex intracellular protein-containing complex non-membrane-bounded organelle membrane-bounded organelle nucleus intracellular membrane-bounded organelle
D	STAGA complex 65 subunit gamma,DhaA,STAGA complex 65 subunit gamma,STAGA complex 65 subunit gamma,DhaA,STAGA complex 65 subunit gamma,STAGA complex 65 subunit gamma,DhaA	protein heterodimerization activity protein binding binding protein dimerization activity transcription coactivator activity transcription regulator activity transcription coregulator activity protein-macromolecule adaptor activity molecular adaptor activity	maintenance of protein location protein localization cellular localization maintenance of protein location in nucleus protein localization to nucleus maintenance of location maintenance of location in cell localization maintenance of protein location in cell cellular macromolecule localization macromolecule localization protein localization to organelle cellular process maintenance of protein localization in organelle maintenance of protein location protein localization cellular localization maintenance of protein location in nucleus protein localization to nucleus maintenance of location maintenance of location in cell localization maintenance of protein location in cell cellular macromolecule localization macromolecule localization protein localization to organelle cellular process maintenance of protein localization in organelle cellular response to stimulus regulation of cellular process response to stimulus regulation of cellular response to stress regulation of primary metabolic process nucleobase-containing compound metabolic process organic substance metabolic process cellular response to stress response to stress regulation of response to stress regulation of nucleobase-containing compound metabolic process DNA repair regulation of biological process biological regulation primary metabolic process DNA metabolic process regulation of macromolecule metabolic process nucleic acid metabolic process regulation of DNA repair organic cyclic compound metabolic process DNA damage response regulation of response to stimulus metabolic process macromolecule metabolic process regulation of metabolic process regulation of DNA metabolic process cellular biosynthetic process RNA metabolic process regulation of RNA metabolic process organic substance biosynthetic process RNA processing regulation of biosynthetic process RNA splicing cellular metabolic process regulation of cellular metabolic process regulation of RNA splicing gene expression macromolecule biosynthetic process regulation of cellular biosynthetic process regulation of gene expression biosynthetic process regulation of macromolecule biosynthetic process positive regulation of macromolecule biosynthetic process positive regulation of metabolic process DNA-templated transcription positive regulation of macromolecule metabolic process positive regulation of nucleobase-containing compound metabolic process positive regulation of RNA metabolic process organic cyclic compound biosynthetic process regulation of DNA-templated transcription positive regulation of DNA-templated transcription positive regulation of biological process positive regulation of cellular metabolic process RNA biosynthetic process nucleic acid biosynthetic process positive regulation of biosynthetic process positive regulation of cellular process regulation of RNA biosynthetic process nucleobase-containing compound biosynthetic process positive regulation of RNA biosynthetic process positive regulation of cellular biosynthetic process	protein-containing complex intracellular anatomical structure catalytic complex peptidase complex protein-DNA complex chromatin chromosome transferase complex cellular anatomical entity histone acetyltransferase complex acetyltransferase complex intracellular organelle organelle intracellular non-membrane-bounded organelle protein-containing complex intracellular anatomical structure catalytic complex peptidase complex protein-DNA complex chromatin chromosome transferase complex cellular anatomical entity histone acetyltransferase complex acetyltransferase complex intracellular organelle organelle intracellular non-membrane-bounded organelle protein acetyltransferase complex SAGA-type complex SAGA complex intracellular protein-containing complex non-membrane-bounded organelle membrane-bounded organelle nucleus membrane-enclosed lumen intracellular membrane-bounded organelle intracellular organelle lumen nucleoplasm organelle lumen nuclear lumen
E	Transcription initiation factor TFIID subunit 9B	transcription corepressor activity transcription regulator activity transcription coregulator activity protein-macromolecule adaptor activity molecular adaptor activity protein heterodimerization activity protein binding binding protein dimerization activity general transcription initiation factor activity RNA polymerase II general transcription initiation factor activity	regulation of biological process regulation of growth regulation of cellular process regulation of cellular component organization positive regulation of biological process biological regulation growth positive regulation of cell growth regulation of cell growth cell growth cellular component organization positive regulation of growth cellular process cellular component organization or biogenesis regulation of biological process regulation of growth regulation of cellular process regulation of cellular component organization positive regulation of biological process biological regulation growth positive regulation of cell growth regulation of cell growth cell growth cellular component organization positive regulation of growth cellular process cellular component organization or biogenesis positive regulation of cellular process cellular response to stimulus response to stimulus negative regulation of biological process regulation of cellular response to stress regulation of signal transduction regulation of intrinsic apoptotic signaling pathway in response to DNA damage regulation of programmed cell death intracellular signal transduction regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator cell communication negative regulation of apoptotic signaling pathway negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator intrinsic apoptotic signaling pathway in response to DNA damage signal transduction intrinsic apoptotic signaling pathway negative regulation of signal transduction by p53 class mediator negative regulation of programmed cell death regulation of apoptotic process cell death negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage negative regulation of apoptotic process regulation of response to stimulus intrinsic apoptotic signaling pathway by p53 class mediator regulation of apoptotic signaling pathway signaling negative regulation of signaling negative regulation of intracellular signal transduction regulation of intrinsic apoptotic signaling pathway negative regulation of cell communication intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator cellular response to stress regulation of intracellular signal transduction response to stress regulation of response to stress regulation of signal transduction by p53 class mediator negative regulation of cellular process regulation of signaling negative regulation of response to stimulus signal transduction by p53 class mediator negative regulation of signal transduction apoptotic signaling pathway negative regulation of intrinsic apoptotic signaling pathway negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator DNA damage response regulation of cell communication apoptotic process regulation of intrinsic apoptotic signaling pathway by p53 class mediator programmed cell death regulation of protein stability regulation of biological quality protein stabilization cellular biosynthetic process cellular metabolic process RNA metabolic process primary metabolic process nucleobase-containing compound biosynthetic process gene expression macromolecule biosynthetic process DNA-templated transcription initiation nucleic acid metabolic process RNA biosynthetic process nucleobase-containing compound metabolic process DNA-templated transcription organic cyclic compound metabolic process nucleic acid biosynthetic process organic substance metabolic process biosynthetic process organic cyclic compound biosynthetic process organic substance biosynthetic process metabolic process macromolecule metabolic process negative regulation of cellular metabolic process regulation of primary metabolic process negative regulation of RNA biosynthetic process regulation of RNA metabolic process transcription by RNA polymerase II negative regulation of nucleobase-containing compound metabolic process regulation of nucleobase-containing compound metabolic process regulation of transcription by RNA polymerase II negative regulation of DNA-templated transcription negative regulation of transcription by RNA polymerase II negative regulation of metabolic process regulation of cellular metabolic process negative regulation of cellular biosynthetic process regulation of gene expression negative regulation of macromolecule biosynthetic process regulation of macromolecule biosynthetic process regulation of DNA-templated transcription regulation of metabolic process negative regulation of RNA metabolic process regulation of RNA biosynthetic process negative regulation of macromolecule metabolic process regulation of biosynthetic process regulation of macromolecule metabolic process regulation of cellular biosynthetic process negative regulation of biosynthetic process	RNA polymerase II transcription regulator complex membrane-bounded organelle transcription factor TFTC complex RNA polymerase II, holoenzyme protein-containing complex intracellular anatomical structure nucleus membrane-enclosed lumen nuclear protein-containing complex transcription regulator complex chromosome transferase complex histone acetyltransferase complex intracellular organelle lumen RNA polymerase II transcription regulator complex membrane-bounded organelle transcription factor TFTC complex RNA polymerase II, holoenzyme protein-containing complex intracellular anatomical structure nucleus membrane-enclosed lumen nuclear protein-containing complex transcription regulator complex chromosome transferase complex histone acetyltransferase complex intracellular organelle lumen intracellular organelle nucleoplasm SAGA-type complex non-membrane-bounded organelle catalytic complex protein-DNA complex chromatin intracellular membrane-bounded organelle cellular anatomical entity acetyltransferase complex transferase complex, transferring phosphorus-containing groups nuclear DNA-directed RNA polymerase complex organelle lumen organelle intracellular non-membrane-bounded organelle RNA polymerase complex protein acetyltransferase complex DNA-directed RNA polymerase complex intracellular protein-containing complex nuclear lumen transcription factor TFIID complex
F	TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L	DNA binding binding organic cyclic compound binding nucleic acid binding protein heterodimerization activity protein binding protein dimerization activity general transcription initiation factor activity RNA polymerase II general transcription initiation factor activity transcription coactivator activity transcription regulator activity transcription coregulator activity protein-macromolecule adaptor activity molecular adaptor activity	regulation of cellular process cellular biosynthetic process RNA metabolic process regulation of primary metabolic process nucleobase-containing compound metabolic process RNA biosynthetic process nucleic acid biosynthetic process DNA-templated transcription regulation of RNA metabolic process organic substance metabolic process organic substance biosynthetic process regulation of nucleobase-containing compound metabolic process regulation of RNA biosynthetic process regulation of biosynthetic process regulation of cellular process cellular biosynthetic process RNA metabolic process regulation of primary metabolic process nucleobase-containing compound metabolic process RNA biosynthetic process nucleic acid biosynthetic process DNA-templated transcription regulation of RNA metabolic process organic substance metabolic process organic substance biosynthetic process regulation of nucleobase-containing compound metabolic process regulation of RNA biosynthetic process regulation of biosynthetic process regulation of biological process cellular metabolic process biological regulation primary metabolic process regulation of cellular metabolic process regulation of macromolecule metabolic process nucleobase-containing compound biosynthetic process gene expression macromolecule biosynthetic process nucleic acid metabolic process regulation of cellular biosynthetic process organic cyclic compound metabolic process regulation of gene expression biosynthetic process organic cyclic compound biosynthetic process metabolic process regulation of macromolecule biosynthetic process cellular process regulation of DNA-templated transcription macromolecule metabolic process regulation of metabolic process transcription preinitiation complex assembly cellular component organization cellular component biogenesis protein-DNA complex organization cellular component assembly transcription by RNA polymerase II protein-containing complex assembly cellular component organization or biogenesis transcription initiation at RNA polymerase II promoter protein-containing complex organization protein-DNA complex assembly DNA-templated transcription initiation RNA polymerase II preinitiation complex assembly positive regulation of macromolecule biosynthetic process positive regulation of metabolic process positive regulation of macromolecule metabolic process positive regulation of nucleobase-containing compound metabolic process positive regulation of RNA metabolic process positive regulation of DNA-templated transcription positive regulation of biological process positive regulation of cellular metabolic process positive regulation of biosynthetic process positive regulation of cellular process positive regulation of RNA biosynthetic process positive regulation of cellular biosynthetic process regulation of transcription by RNA polymerase II cellular response to stimulus response to stimulus regulation of cellular response to stress cellular response to stress response to stress regulation of response to stress DNA repair DNA metabolic process regulation of DNA repair DNA damage response regulation of response to stimulus regulation of DNA metabolic process RNA processing RNA splicing regulation of RNA splicing chromatin organization chromatin remodeling developmental process regulation of somatic stem cell population maintenance multicellular organismal process regulation of developmental process regulation of stem cell population maintenance stem cell population maintenance somatic stem cell population maintenance regulation of multicellular organismal process maintenance of cell number	protein-containing complex intracellular anatomical structure catalytic complex peptidase complex protein-DNA complex chromatin chromosome transferase complex cellular anatomical entity histone acetyltransferase complex acetyltransferase complex intracellular organelle organelle intracellular non-membrane-bounded organelle protein-containing complex intracellular anatomical structure catalytic complex peptidase complex protein-DNA complex chromatin chromosome transferase complex cellular anatomical entity histone acetyltransferase complex acetyltransferase complex intracellular organelle organelle intracellular non-membrane-bounded organelle protein acetyltransferase complex SAGA-type complex SAGA complex intracellular protein-containing complex non-membrane-bounded organelle extracellular exosome membrane-bounded organelle extracellular vesicle extracellular organelle extracellular region extracellular space vesicle extracellular membrane-bounded organelle nucleus membrane-enclosed lumen nuclear protein-containing complex intracellular membrane-bounded organelle intracellular organelle lumen histone deacetylase complex nucleoplasm organelle lumen nuclear lumen RNA polymerase II transcription regulator complex RNA polymerase II, holoenzyme transcription regulator complex transferase complex, transferring phosphorus-containing groups nuclear DNA-directed RNA polymerase complex RNA polymerase complex transcription factor TFIID complex DNA-directed RNA polymerase complex SLIK (SAGA-like) complex
G	Transcription initiation factor TFIID subunit 12	protein heterodimerization activity protein binding binding protein dimerization activity transcription coactivator activity transcription regulator activity transcription coregulator activity protein-macromolecule adaptor activity molecular adaptor activity DNA binding organic cyclic compound binding nucleic acid binding transcription factor binding TBP-class protein binding protein heterodimerization activity protein binding binding protein dimerization activity transcription coactivator activity transcription regulator activity transcription coregulator activity protein-macromolecule adaptor activity molecular adaptor activity DNA binding organic cyclic compound binding nucleic acid binding transcription factor binding TBP-class protein binding general transcription initiation factor binding DNA-binding transcription factor binding	cellular biosynthetic process transcription preinitiation complex assembly RNA metabolic process cellular component organization cellular component biogenesis protein-DNA complex organization RNA biosynthetic process nucleobase-containing compound metabolic process DNA-templated transcription nucleic acid biosynthetic process cellular component assembly organic substance metabolic process transcription by RNA polymerase II protein-containing complex assembly organic substance biosynthetic process cellular biosynthetic process transcription preinitiation complex assembly RNA metabolic process cellular component organization cellular component biogenesis protein-DNA complex organization RNA biosynthetic process nucleobase-containing compound metabolic process DNA-templated transcription nucleic acid biosynthetic process cellular component assembly organic substance metabolic process transcription by RNA polymerase II protein-containing complex assembly organic substance biosynthetic process cellular component organization or biogenesis transcription initiation at RNA polymerase II promoter protein-containing complex organization cellular metabolic process protein-DNA complex assembly primary metabolic process nucleobase-containing compound biosynthetic process gene expression macromolecule biosynthetic process DNA-templated transcription initiation nucleic acid metabolic process organic cyclic compound metabolic process biosynthetic process organic cyclic compound biosynthetic process RNA polymerase II preinitiation complex assembly cellular process metabolic process macromolecule metabolic process regulation of cellular process positive regulation of macromolecule biosynthetic process regulation of primary metabolic process positive regulation of metabolic process regulation of DNA-templated transcription initiation regulation of RNA metabolic process positive regulation of macromolecule metabolic process regulation of nucleobase-containing compound metabolic process regulation of transcription by RNA polymerase II regulation of biological process positive regulation of nucleobase-containing compound metabolic process regulation of cellular metabolic process positive regulation of transcription by RNA polymerase II positive regulation of DNA-templated transcription initiation positive regulation of RNA metabolic process regulation of gene expression regulation of macromolecule biosynthetic process regulation of DNA-templated transcription regulation of metabolic process positive regulation of DNA-templated transcription positive regulation of biological process positive regulation of cellular metabolic process positive regulation of biosynthetic process positive regulation of cellular process regulation of RNA biosynthetic process regulation of biosynthetic process positive regulation of transcription initiation by RNA polymerase II biological regulation regulation of macromolecule metabolic process regulation of cellular biosynthetic process positive regulation of RNA biosynthetic process regulation of transcription initiation by RNA polymerase II positive regulation of cellular biosynthetic process mRNA transcription by RNA polymerase II mRNA transcription mRNA metabolic process cellular response to stimulus response to stimulus regulation of cellular response to stress cellular response to stress response to stress regulation of response to stress DNA repair DNA metabolic process regulation of DNA repair DNA damage response regulation of response to stimulus regulation of DNA metabolic process RNA processing RNA splicing regulation of RNA splicing	RNA polymerase II transcription regulator complex membrane-bounded organelle RNA polymerase II, holoenzyme protein-containing complex intracellular anatomical structure nucleus membrane-enclosed lumen nuclear protein-containing complex transcription regulator complex transferase complex intracellular organelle lumen intracellular organelle nucleoplasm catalytic complex RNA polymerase II transcription regulator complex membrane-bounded organelle RNA polymerase II, holoenzyme protein-containing complex intracellular anatomical structure nucleus membrane-enclosed lumen nuclear protein-containing complex transcription regulator complex transferase complex intracellular organelle lumen intracellular organelle nucleoplasm catalytic complex intracellular membrane-bounded organelle cellular anatomical entity transferase complex, transferring phosphorus-containing groups nuclear DNA-directed RNA polymerase complex organelle lumen organelle RNA polymerase complex transcription factor TFIID complex DNA-directed RNA polymerase complex intracellular protein-containing complex nuclear lumen protein-DNA complex chromatin chromosome histone acetyltransferase complex acetyltransferase complex intracellular non-membrane-bounded organelle protein acetyltransferase complex SAGA-type complex SLIK (SAGA-like) complex non-membrane-bounded organelle peptidase complex SAGA complex transcription factor TFTC complex

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
H	IPR003923	Transcription initiation factor TFIID, 23-30kDa subunit	Family
I	IPR009072	Histone-fold	Homologous Superfamily
I	IPR003195	Transcription initiation factor IID, subunit 13	Family
A	IPR016024	Armadillo-type fold	Homologous Superfamily
A	IPR003152	FATC domain	Domain
A	IPR011989	Armadillo-like helical	Homologous Superfamily
A	IPR046805	Tra1, HEAT repeat ring region	Repeat
A	IPR000403	Phosphatidylinositol 3-/4-kinase, catalytic domain	Domain
A	IPR046807	Tra1, HEAT repeat central region	Repeat
A	IPR003151	PIK-related kinase, FAT	Domain
A	IPR011009	Protein kinase-like domain superfamily	Homologous Superfamily
A	IPR014009	PIK-related kinase	Domain
J	IPR024738	Transcriptional coactivator Hfi1/Transcriptional adapter 1	Family
K [auth N]	IPR013243	SCA7 domain	Domain
B	IPR007582	TFIID subunit TAF5, NTD2 domain	Domain
B	IPR019775	WD40 repeat, conserved site	Conserved Site
B	IPR037264	TFIID subunit TAF5, NTD2 domain superfamily	Homologous Superfamily
B	IPR036322	WD40-repeat-containing domain superfamily	Homologous Superfamily
B	IPR001680	WD40 repeat	Repeat
B	IPR020472	G-protein beta WD-40 repeat	Repeat
B	IPR015943	WD40/YVTN repeat-like-containing domain superfamily	Homologous Superfamily
C	IPR021950	Transcription factor Spt20	Family
C	IPR046468	Spt20-like, SEP domain	Domain
D	IPR009072	Histone-fold	Homologous Superfamily
D	IPR006565	Bromodomain associated domain	Domain
D	IPR039460	STAGA complex 65 subunit gamma	Family
E	IPR009072	Histone-fold	Homologous Superfamily
E	IPR003162	Transcription initiation factor TAFII31	Family
F	IPR009072	Histone-fold	Homologous Superfamily
F	IPR011442	TAF6, C-terminal HEAT repeat domain	Domain
F	IPR037796	Transcription initiation factor TFIID subunit 6	Family
F	IPR046344	TAF6, C-terminal HEAT repeat domain superfamily	Homologous Superfamily
F	IPR004823	TATA box binding protein associated factor (TAF), histone-like fold domain	Domain
G	IPR009072	Histone-fold	Homologous Superfamily
G	IPR037794	Transcription initiation factor TFIID subunit 12	Family
G	IPR003228	Transcription initiation factor TFIID subunit 12 domain	Domain

Pharos: Disease Associations Pharos Homepage Annotation

Chains	Drug Target	Associated Disease
H	Pharos: Q12962	Gaucher disease pancreatic intraductal papillary-mucinous neoplasm osteosarcoma ovarian cancer
I	Pharos: O75486	medulloblastoma osteoarthritis metaphyseal dysplasia-maxillary hypoplasia-brachydacty syndrome pancreatic intraductal papillary-mucinous neoplasm ossification of the posterior longitudinal ligament of the spine tuberculosis
A	Pharos: Q9Y4A5	melanoma schizophrenia cutaneous melanoma ovarian mucinous adenocarcinoma adenoma atypical teratoid rhabdoid tumor gastric adenocarcinoma large cell medulloblastoma malignant ependymoma osteosarcoma ovarian serous adenocarcinoma subependymal giant cell astrocytoma adrenal cortex carcinoma colorectal adenocarcinoma Gaucher disease melanoma schizophrenia cutaneous melanoma ovarian mucinous adenocarcinoma adenoma atypical teratoid rhabdoid tumor gastric adenocarcinoma large cell medulloblastoma malignant ependymoma osteosarcoma ovarian serous adenocarcinoma subependymal giant cell astrocytoma adrenal cortex carcinoma colorectal adenocarcinoma Gaucher disease lung adenocarcinoma malignant mesothelioma nonsyndromic genetic deafness ovarian cancer primitive neuroectodermal tumor astrocytic tumor glioblastoma lung large cell carcinoma medulloblastoma oligodendroglioma
J	Pharos: Q96BN2	medulloblastoma subependymal giant cell astrocytoma
K [auth N]	Pharos: O15265	spinocerebellar ataxia type 7 autosomal dominant cerebellar ataxia Gait Ataxia hyperreflexia neurodegenerative disease vision disorder lung cancer astrocytic tumor non-small cell lung carcinoma spina bifida ovarian cancer spinocerebellar ataxia type 4 breast carcinoma pancreatic intraductal papillary-mucinous neoplasm with low grade dysplasia cerebellar ataxia spinocerebellar ataxia type 7 autosomal dominant cerebellar ataxia Gait Ataxia hyperreflexia neurodegenerative disease vision disorder lung cancer astrocytic tumor non-small cell lung carcinoma spina bifida ovarian cancer spinocerebellar ataxia type 4 breast carcinoma pancreatic intraductal papillary-mucinous neoplasm with low grade dysplasia cerebellar ataxia dermatomyositis hereditary ataxia rheumatoid arthritis oligodendroglioma spinocerebellar ataxia type 1 brain disease spinocerebellar ataxia type 5 Pick disease glioblastoma intellectual disability medulloblastoma movement disorder skin disease atypical teratoid rhabdoid tumor osteosarcoma spinocerebellar ataxia type 2 breast cancer pancreatic ductal adenocarcinoma spinocerebellar ataxia type 6
B	Pharos: O75529	osteosarcoma tuberculosis pancreatic intraductal papillary-mucinous neoplasm psoriasis
C	Pharos: Q8NEM7	juvenile dermatomyositis medulloblastoma pancreatic intraductal papillary-mucinous carcinoma primitive neuroectodermal tumor tuberculosis malignant mesothelioma ovarian cancer pancreatic intraductal papillary-mucinous neoplasm with low grade dysplasia progressive supranuclear palsy malignant pancreatic neoplasm pancreatic ductal adenocarcinoma Pick disease psoriasis
D	Pharos: O94864	large cell medulloblastoma osteosarcoma psoriasis metabolic syndrome X ovarian cancer oral cavity cancer Pick disease
E	Pharos: Q9HBM6	lung carcinoma osteosarcoma Pick disease malignant ependymoma ovarian cancer medulloblastoma pancreatic intraductal papillary-mucinous neoplasm
F	Pharos: Q9Y6J9	atypical teratoid rhabdoid tumor osteosarcoma psoriasis
G	Pharos: Q16514	lung adenocarcinoma