Annotations: 7JRJ

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
C [auth K]	d7jrjk_	Alpha and beta proteins (a+b)	Ferredoxin-like	Nucleoside diphosphate kinase, NDK	automated matches	automated matches	(Chlamydomonas reinhardtii ) [TaxId: 3055 ],	SCOPe (2.08)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
C [auth K]	PF00334	e7jrjK1	A: a+b two layers	X: Alpha-beta plaits	H: Nucleoside diphosphate kinases (From Topology)	T: Nucleoside diphosphate kinases	F: PF00334	ECOD (1.6)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A [auth E]	PF02493	MORN repeat (MORN)	MORN repeat	-	Repeat
B [auth F]	PF02493	MORN repeat (MORN)	MORN repeat	-	Repeat
C [auth K]	PF00334	Nucleoside diphosphate kinase (NDK)	Nucleoside diphosphate kinase	-	Domain
D [auth I]	PF05186	Dpy-30 motif (Dpy-30)	Dpy-30 motif	-	Motif
F [auth G]	PF06098	Radial spoke protein 3 (Radial_spoke_3)	Radial spoke protein 3	-	Family
G [auth H]	PF00248	Aldo/keto reductase family (Aldo_ket_red)	Aldo/keto reductase family	This family includes a number of K+ ion channel beta chain regulatory domains - these are reported to have oxidoreductase activity [2].	Domain
K [auth D]	PF04712	Radial spokehead-like protein (Radial_spoke)	Radial spokehead-like protein	-	Family
J [auth C]	PF04712	Radial spokehead-like protein (Radial_spoke)	Radial spokehead-like protein	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A [auth E]	Radial spoke protein 10	-	-	membrane cellular anatomical entity
B [auth F]	Flagellar radial spoke protein 1	-	-	membrane cellular anatomical entity intracellular anatomical structure cytoplasm intracellular organelle cytoskeleton organelle intracellular non-membrane-bounded organelle non-membrane-bounded organelle membrane-bounded organelle cell projection cilium motile cilium plasma membrane bounded cell projection
C [auth K]	Nucleoside diphosphate kinase 6	binding adenyl ribonucleotide binding nucleotide binding purine ribonucleotide binding purine ribonucleoside triphosphate binding nucleoside phosphate binding ion binding purine nucleotide binding organic cyclic compound binding anion binding adenyl nucleotide binding ATP binding heterocyclic compound binding carbohydrate derivative binding binding adenyl ribonucleotide binding nucleotide binding purine ribonucleotide binding purine ribonucleoside triphosphate binding nucleoside phosphate binding ion binding purine nucleotide binding organic cyclic compound binding anion binding adenyl nucleotide binding ATP binding heterocyclic compound binding carbohydrate derivative binding ribonucleotide binding small molecule binding nucleobase-containing compound kinase activity kinase activity transferase activity catalytic activity phosphotransferase activity, phosphate group as acceptor nucleoside diphosphate kinase activity transferase activity, transferring phosphorus-containing groups cation binding metal ion binding	ribose phosphate metabolic process nucleotide biosynthetic process organonitrogen compound biosynthetic process carbohydrate derivative metabolic process pyrimidine nucleotide metabolic process nucleobase-containing compound metabolic process ribonucleotide biosynthetic process organic substance metabolic process ribonucleotide metabolic process pyrimidine ribonucleoside triphosphate biosynthetic process nucleobase-containing small molecule metabolic process phosphate-containing compound metabolic process organic substance biosynthetic process small molecule metabolic process ribose phosphate metabolic process nucleotide biosynthetic process organonitrogen compound biosynthetic process carbohydrate derivative metabolic process pyrimidine nucleotide metabolic process nucleobase-containing compound metabolic process ribonucleotide biosynthetic process organic substance metabolic process ribonucleotide metabolic process pyrimidine ribonucleoside triphosphate biosynthetic process nucleobase-containing small molecule metabolic process phosphate-containing compound metabolic process organic substance biosynthetic process small molecule metabolic process pyrimidine nucleoside triphosphate biosynthetic process pyrimidine-containing compound biosynthetic process phosphorus metabolic process ribose phosphate biosynthetic process pyrimidine ribonucleotide metabolic process ribonucleoside triphosphate metabolic process nucleoside phosphate metabolic process carbohydrate derivative biosynthetic process pyrimidine-containing compound metabolic process organonitrogen compound metabolic process pyrimidine nucleoside triphosphate metabolic process nucleoside triphosphate biosynthetic process cellular metabolic process primary metabolic process nucleotide metabolic process nucleobase-containing compound biosynthetic process ribonucleoside triphosphate biosynthetic process organic cyclic compound metabolic process biosynthetic process organophosphate metabolic process organophosphate biosynthetic process organic cyclic compound biosynthetic process nucleoside phosphate biosynthetic process pyrimidine ribonucleoside triphosphate metabolic process metabolic process cellular process UTP biosynthetic process nucleoside triphosphate metabolic process UTP metabolic process pyrimidine nucleotide biosynthetic process pyrimidine ribonucleotide biosynthetic process GTP metabolic process GTP biosynthetic process purine ribonucleotide biosynthetic process purine ribonucleoside triphosphate biosynthetic process purine nucleotide metabolic process purine nucleoside triphosphate biosynthetic process purine-containing compound biosynthetic process purine ribonucleoside triphosphate metabolic process purine nucleoside triphosphate metabolic process purine-containing compound metabolic process purine ribonucleotide metabolic process purine nucleotide biosynthetic process phosphorylation CTP biosynthetic process CTP metabolic process	intracellular anatomical structure cytoplasm cellular anatomical entity membrane-bounded organelle cell projection organelle cilium motile cilium plasma membrane bounded cell projection
D [auth I]	Flagellar radial spoke protein 2	protein binding binding calmodulin binding	-	intracellular anatomical structure cytoplasm cellular anatomical entity intracellular organelle cytoskeleton organelle intracellular non-membrane-bounded organelle non-membrane-bounded organelle membrane-bounded organelle cell projection cilium motile cilium plasma membrane bounded cell projection protein-containing complex intracellular anatomical structure cytoplasm cellular anatomical entity intracellular organelle cytoskeleton organelle intracellular non-membrane-bounded organelle non-membrane-bounded organelle membrane-bounded organelle cell projection cilium motile cilium plasma membrane bounded cell projection protein-containing complex Set1C/COMPASS complex histone methyltransferase complex catalytic complex nucleus membrane-enclosed lumen nuclear protein-containing complex intracellular membrane-bounded organelle transferase complex intracellular organelle lumen nucleoplasm organelle lumen methyltransferase complex nuclear lumen
E [auth J]	unknown protein	-	-	-
F [auth G]	Flagellar radial spoke protein 3	-	positive regulation of locomotion regulation of biological process regulation of cell motility regulation of cellular process positive regulation of cilium-dependent cell motility biological regulation positive regulation of biological process regulation of cilium-dependent cell motility cilium or flagellum-dependent cell motility cilium-dependent cell motility regulation of locomotion positive regulation of cell motility cellular process cell motility positive regulation of locomotion regulation of biological process regulation of cell motility regulation of cellular process positive regulation of cilium-dependent cell motility biological regulation positive regulation of biological process regulation of cilium-dependent cell motility cilium or flagellum-dependent cell motility cilium-dependent cell motility regulation of locomotion positive regulation of cell motility cellular process cell motility locomotion positive regulation of cellular process	membrane-bounded organelle protein-containing complex intracellular anatomical structure axoneme ciliary plasm radial spoke cilium cellular anatomical entity cytoplasmic region plasma membrane bounded cell projection cytoplasm plasma membrane bounded cell projection intracellular organelle cell projection cytoskeleton membrane-bounded organelle protein-containing complex intracellular anatomical structure axoneme ciliary plasm radial spoke cilium cellular anatomical entity cytoplasmic region plasma membrane bounded cell projection cytoplasm plasma membrane bounded cell projection intracellular organelle cell projection cytoskeleton organelle intracellular non-membrane-bounded organelle cytoplasm non-membrane-bounded organelle motile cilium
G [auth H]	Flagellar radial spoke protein 5	oxidoreductase activity catalytic activity	-	intracellular anatomical structure cytoplasm cellular anatomical entity intracellular organelle cytoskeleton organelle intracellular non-membrane-bounded organelle non-membrane-bounded organelle membrane-bounded organelle cell projection cilium motile cilium plasma membrane bounded cell projection
L	Flagellar radial spoke protein 6	-	-	-
M	Flagellar radial spoke protein 10	-	-	-
N	Flagellar radial spoke protein 1	-	-	-
O	Flagellar radial spoke protein 2	-	-	-
K [auth D]	Flagellar radial spoke protein 6	-	cilium-dependent cell motility cellular process microtubule-based movement microtubule-based process cilium movement involved in cell motility cilium movement cell motility cilium or flagellum-dependent cell motility organelle assembly plasma membrane bounded cell projection organization cell projection organization plasma membrane bounded cell projection assembly cellular component biogenesis cellular component organization cilium-dependent cell motility cellular process microtubule-based movement microtubule-based process cilium movement involved in cell motility cilium movement cell motility cilium or flagellum-dependent cell motility organelle assembly plasma membrane bounded cell projection organization cell projection organization plasma membrane bounded cell projection assembly cellular component biogenesis cellular component organization organelle organization cellular component assembly cilium assembly cellular component organization or biogenesis cilium organization cell projection assembly	membrane-bounded organelle radial spoke head protein-containing complex intracellular anatomical structure axoneme ciliary plasm radial spoke cilium cellular anatomical entity cytoplasmic region plasma membrane bounded cell projection cytoplasm plasma membrane bounded cell projection intracellular organelle cell projection membrane-bounded organelle radial spoke head protein-containing complex intracellular anatomical structure axoneme ciliary plasm radial spoke cilium cellular anatomical entity cytoplasmic region plasma membrane bounded cell projection cytoplasm plasma membrane bounded cell projection intracellular organelle cell projection cytoskeleton organelle intracellular non-membrane-bounded organelle cytoplasm non-membrane-bounded organelle motile cilium
H [auth A], I [auth B]	Radial spoke protein 9	-	organelle assembly plasma membrane bounded cell projection organization motile cilium assembly cell projection organization plasma membrane bounded cell projection assembly cellular component biogenesis cellular component organization organelle organization cellular component assembly cilium assembly cellular process cellular component organization or biogenesis cilium organization cell projection assembly organelle assembly plasma membrane bounded cell projection organization motile cilium assembly cell projection organization plasma membrane bounded cell projection assembly cellular component biogenesis cellular component organization organelle organization cellular component assembly cilium assembly cellular process cellular component organization or biogenesis cilium organization cell projection assembly cilium-dependent cell motility microtubule-based movement microtubule-based process cilium movement involved in cell motility cilium movement cell motility cilium or flagellum-dependent cell motility microtubule cytoskeleton organization microtubule bundle formation axoneme assembly cytoskeleton organization	membrane-bounded organelle 9+2 non-motile cilium non-motile cilium stereocilium bundle cilium neuron projection cellular anatomical entity kinocilium cluster of actin-based cell projections plasma membrane bounded cell projection cell projection organelle intracellular anatomical structure axoneme membrane-bounded organelle 9+2 non-motile cilium non-motile cilium stereocilium bundle cilium neuron projection cellular anatomical entity kinocilium cluster of actin-based cell projections plasma membrane bounded cell projection cell projection organelle intracellular anatomical structure axoneme ciliary plasm cytoplasmic region plasma membrane bounded cell projection cytoplasm intracellular organelle cytoskeleton intracellular non-membrane-bounded organelle cytoplasm non-membrane-bounded organelle
J [auth C]	Flagellar radial spoke protein 4	-	cilium-dependent cell motility cellular process microtubule-based movement microtubule-based process cilium movement involved in cell motility cilium movement cell motility cilium or flagellum-dependent cell motility organelle assembly plasma membrane bounded cell projection organization cell projection organization plasma membrane bounded cell projection assembly cellular component biogenesis cellular component organization cilium-dependent cell motility cellular process microtubule-based movement microtubule-based process cilium movement involved in cell motility cilium movement cell motility cilium or flagellum-dependent cell motility organelle assembly plasma membrane bounded cell projection organization cell projection organization plasma membrane bounded cell projection assembly cellular component biogenesis cellular component organization organelle organization cellular component assembly cilium assembly cellular component organization or biogenesis cilium organization cell projection assembly	membrane-bounded organelle protein-containing complex intracellular anatomical structure axoneme ciliary plasm radial spoke cilium cellular anatomical entity cytoplasmic region plasma membrane bounded cell projection cytoplasm plasma membrane bounded cell projection intracellular organelle cell projection cytoskeleton membrane-bounded organelle protein-containing complex intracellular anatomical structure axoneme ciliary plasm radial spoke cilium cellular anatomical entity cytoplasmic region plasma membrane bounded cell projection cytoplasm plasma membrane bounded cell projection intracellular organelle cell projection cytoskeleton organelle intracellular non-membrane-bounded organelle cytoplasm non-membrane-bounded organelle radial spoke head motile cilium

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A [auth E]	IPR003409	MORN repeat	Repeat
B [auth F]	IPR003409	MORN repeat	Repeat
C [auth K]	IPR034907	Nucleoside diphosphate kinase-like domain	Domain
C [auth K]	IPR037994	Nucleoside diphosphate kinase 6	Family
C [auth K]	IPR023005	Nucleoside diphosphate kinase, active site	Active Site
C [auth K]	IPR000048	IQ motif, EF-hand binding site	Binding Site
C [auth K]	IPR036850	Nucleoside diphosphate kinase-like domain superfamily	Homologous Superfamily
C [auth K]	IPR001564	Nucleoside diphosphate kinase	Family
D [auth I]	IPR007858	Dpy-30 motif	Conserved Site
D [auth I]	IPR037856	Sdc1/DPY30	Family
F [auth G]	IPR009290	Radial spoke 3	Family
G [auth H]	IPR036812	NADP-dependent oxidoreductase domain superfamily	Homologous Superfamily
G [auth H]	IPR023210	NADP-dependent oxidoreductase domain	Domain
K [auth D]	IPR006802	Radial spokehead-like protein	Family
J [auth C]	IPR006802	Radial spokehead-like protein	Family

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.