Annotations: 7DEK

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2B Superfamily	Rotamase-like	8104357	3000622	SCOP2B (2022-06-29)
B [auth G]	SCOP2B Superfamily	Rotamase-like	8104357	3000622	SCOP2B (2022-06-29)
C [auth F]	SCOP2 Family	FKBP immunophilin/proline isomerase	8104356	4001062	SCOP2 (2022-06-29)
C [auth F]	SCOP2 Superfamily	Rotamase-like	8104357	3000622	SCOP2 (2022-06-29)
D	SCOP2B Superfamily	Rotamase-like	8104357	3000622	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	PF01346	e7dekA2	A: alpha duplicates or obligate multimers	X: FkpA dimerization domain-like (From Topology)	H: FkpA dimerization domain-like (From Topology)	T: FkpA dimerization domain-like	F: PF01346	ECOD (1.6)
A	PF00254,PF01346	e7dekA1	A: a+b two layers	X: FKBP-like	H: FKBP-like	T: FKBP-like	F: PF00254,PF01346	ECOD (1.6)
B [auth G]	PF01346	e7dekG2	A: alpha duplicates or obligate multimers	X: FkpA dimerization domain-like (From Topology)	H: FkpA dimerization domain-like (From Topology)	T: FkpA dimerization domain-like	F: PF01346	ECOD (1.6)
B [auth G]	PF00254,PF01346	e7dekG1	A: a+b two layers	X: FKBP-like	H: FKBP-like	T: FKBP-like	F: PF00254,PF01346	ECOD (1.6)
C [auth F]	PF01346	e7dekF2	A: alpha duplicates or obligate multimers	X: FkpA dimerization domain-like (From Topology)	H: FkpA dimerization domain-like (From Topology)	T: FkpA dimerization domain-like	F: PF01346	ECOD (1.6)
C [auth F]	PF00254,PF01346	e7dekF1	A: a+b two layers	X: FKBP-like	H: FKBP-like	T: FKBP-like	F: PF00254,PF01346	ECOD (1.6)
D	PF01346	e7dekD2	A: alpha duplicates or obligate multimers	X: FkpA dimerization domain-like (From Topology)	H: FkpA dimerization domain-like (From Topology)	T: FkpA dimerization domain-like	F: PF01346	ECOD (1.6)
D	PF00254,PF01346	e7dekD1	A: a+b two layers	X: FKBP-like	H: FKBP-like	T: FKBP-like	F: PF00254,PF01346	ECOD (1.6)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B [auth G], C [auth F], D	PF00254	FKBP-type peptidyl-prolyl cis-trans isomerase (FKBP_C)	FKBP-type peptidyl-prolyl cis-trans isomerase	-	Domain
A, B [auth G], C [auth F], D	PF01346	Domain amino terminal to FKBP-type peptidyl-prolyl isomerase (FKBP_N)	Domain amino terminal to FKBP-type peptidyl-prolyl isomerase	This family is only found at the amino terminus of Pfam:PF00254. This entry represents the N-terminal domain found in FKBP-type peptidylprolyl isomerases (PPIase). The N-terminal domain forms the dimer interface by the mutual exchange of two beta-str ...	This family is only found at the amino terminus of Pfam:PF00254. This entry represents the N-terminal domain found in FKBP-type peptidylprolyl isomerases (PPIase). The N-terminal domain forms the dimer interface by the mutual exchange of two beta-strands between monomers [1].	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B [auth G], C [auth F], D	Peptidyl-prolyl cis-trans isomerase	isomerase activity catalytic activity, acting on a protein peptidyl-prolyl cis-trans isomerase activity catalytic activity cis-trans isomerase activity	organonitrogen compound metabolic process cellular biosynthetic process cellular metabolic process primary metabolic process gene expression macromolecule biosynthetic process protein maturation organic substance metabolic process protein folding biosynthetic process organic substance biosynthetic process metabolic process cellular process protein metabolic process organonitrogen compound metabolic process cellular biosynthetic process cellular metabolic process primary metabolic process gene expression macromolecule biosynthetic process protein maturation organic substance metabolic process protein folding biosynthetic process organic substance biosynthetic process metabolic process cellular process protein metabolic process macromolecule metabolic process	-

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B [auth G], C [auth F], D	IPR046357	Peptidyl-prolyl cis-trans isomerase domain superfamily	Homologous Superfamily
A, B [auth G], C [auth F], D	IPR000774	Peptidyl-prolyl cis-trans isomerase, FKBP-type, N-terminal	Domain
A, B [auth G], C [auth F], D	IPR001179	FKBP-type peptidyl-prolyl cis-trans isomerase domain	Domain
A, B [auth G], C [auth F], D	IPR036944	Peptidyl-prolyl cis-trans isomerase, FKBP-type, N-terminal domain superfamily	Homologous Superfamily

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.