Annotations: 7DDE

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	PF02127	e7ddeA2	A: beta barrels	X: cradle loop barrel	H: RIFT-related	T: Alanine racemase-C	F: PF02127	ECOD (1.6)
A	PF02127	e7ddeA1	A: a/b three-layered sandwiches	X: Phosphorylase/hydrolase-like	H: Zn-dependent exopeptidases (From Topology)	T: Zn-dependent exopeptidases	F: PF02127	ECOD (1.6)
A	PF00569	e7ddeA3	A: few secondary structure elements	X: RING/U-box-like	H: RING/U-box-like	T: RING/U-box	F: PF00569	ECOD (1.6)
B [auth C]	PF02127	e7ddeC2	A: beta barrels	X: cradle loop barrel	H: RIFT-related	T: Alanine racemase-C	F: PF02127	ECOD (1.6)
B [auth C]	PF02127	e7ddeC1	A: a/b three-layered sandwiches	X: Phosphorylase/hydrolase-like	H: Zn-dependent exopeptidases (From Topology)	T: Zn-dependent exopeptidases	F: PF02127	ECOD (1.6)
B [auth C]	PF00569	e7ddeC3	A: few secondary structure elements	X: RING/U-box-like	H: RING/U-box-like	T: RING/U-box	F: PF00569	ECOD (1.6)
C [auth E]	PF02127	e7ddeE2	A: beta barrels	X: cradle loop barrel	H: RIFT-related	T: Alanine racemase-C	F: PF02127	ECOD (1.6)
C [auth E]	PF02127	e7ddeE1	A: a/b three-layered sandwiches	X: Phosphorylase/hydrolase-like	H: Zn-dependent exopeptidases (From Topology)	T: Zn-dependent exopeptidases	F: PF02127	ECOD (1.6)
C [auth E]	PF00569	e7ddeE3	A: few secondary structure elements	X: RING/U-box-like	H: RING/U-box-like	T: RING/U-box	F: PF00569	ECOD (1.6)
D [auth G]	PF02127	e7ddeG2	A: beta barrels	X: cradle loop barrel	H: RIFT-related	T: Alanine racemase-C	F: PF02127	ECOD (1.6)
D [auth G]	PF02127	e7ddeG1	A: a/b three-layered sandwiches	X: Phosphorylase/hydrolase-like	H: Zn-dependent exopeptidases (From Topology)	T: Zn-dependent exopeptidases	F: PF02127	ECOD (1.6)
D [auth G]	PF00569	e7ddeG3	A: few secondary structure elements	X: RING/U-box-like	H: RING/U-box-like	T: RING/U-box	F: PF00569	ECOD (1.6)
E [auth I]	PF02127	e7ddeI2	A: beta barrels	X: cradle loop barrel	H: RIFT-related	T: Alanine racemase-C	F: PF02127	ECOD (1.6)
E [auth I]	PF02127	e7ddeI1	A: a/b three-layered sandwiches	X: Phosphorylase/hydrolase-like	H: Zn-dependent exopeptidases (From Topology)	T: Zn-dependent exopeptidases	F: PF02127	ECOD (1.6)
E [auth I]	PF00569	e7ddeI3	A: few secondary structure elements	X: RING/U-box-like	H: RING/U-box-like	T: RING/U-box	F: PF00569	ECOD (1.6)
F [auth K]	PF02127	e7ddeK2	A: beta barrels	X: cradle loop barrel	H: RIFT-related	T: Alanine racemase-C	F: PF02127	ECOD (1.6)
F [auth K]	PF02127	e7ddeK1	A: a/b three-layered sandwiches	X: Phosphorylase/hydrolase-like	H: Zn-dependent exopeptidases (From Topology)	T: Zn-dependent exopeptidases	F: PF02127	ECOD (1.6)
F [auth K]	PF00569	e7ddeK3	A: few secondary structure elements	X: RING/U-box-like	H: RING/U-box-like	T: RING/U-box	F: PF00569	ECOD (1.6)
G [auth M]	PF02127	e7ddeM2	A: beta barrels	X: cradle loop barrel	H: RIFT-related	T: Alanine racemase-C	F: PF02127	ECOD (1.6)
G [auth M]	PF02127	e7ddeM1	A: a/b three-layered sandwiches	X: Phosphorylase/hydrolase-like	H: Zn-dependent exopeptidases (From Topology)	T: Zn-dependent exopeptidases	F: PF02127	ECOD (1.6)
G [auth M]	PF00569	e7ddeM3	A: few secondary structure elements	X: RING/U-box-like	H: RING/U-box-like	T: RING/U-box	F: PF00569	ECOD (1.6)
H [auth O]	PF02127	e7ddeO2	A: beta barrels	X: cradle loop barrel	H: RIFT-related	T: Alanine racemase-C	F: PF02127	ECOD (1.6)
H [auth O]	PF02127	e7ddeO1	A: a/b three-layered sandwiches	X: Phosphorylase/hydrolase-like	H: Zn-dependent exopeptidases (From Topology)	T: Zn-dependent exopeptidases	F: PF02127	ECOD (1.6)
H [auth O]	PF00569	e7ddeO3	A: few secondary structure elements	X: RING/U-box-like	H: RING/U-box-like	T: RING/U-box	F: PF00569	ECOD (1.6)
I [auth Q]	PF02127	e7ddeQ2	A: beta barrels	X: cradle loop barrel	H: RIFT-related	T: Alanine racemase-C	F: PF02127	ECOD (1.6)
I [auth Q]	PF02127	e7ddeQ1	A: a/b three-layered sandwiches	X: Phosphorylase/hydrolase-like	H: Zn-dependent exopeptidases (From Topology)	T: Zn-dependent exopeptidases	F: PF02127	ECOD (1.6)
I [auth Q]	PF00569	e7ddeQ3	A: few secondary structure elements	X: RING/U-box-like	H: RING/U-box-like	T: RING/U-box	F: PF00569	ECOD (1.6)
J [auth S]	PF02127	e7ddeS2	A: beta barrels	X: cradle loop barrel	H: RIFT-related	T: Alanine racemase-C	F: PF02127	ECOD (1.6)
J [auth S]	PF02127	e7ddeS1	A: a/b three-layered sandwiches	X: Phosphorylase/hydrolase-like	H: Zn-dependent exopeptidases (From Topology)	T: Zn-dependent exopeptidases	F: PF02127	ECOD (1.6)
J [auth S]	PF00569	e7ddeS3	A: few secondary structure elements	X: RING/U-box-like	H: RING/U-box-like	T: RING/U-box	F: PF00569	ECOD (1.6)
K [auth V]	PF02127	e7ddeV2	A: beta barrels	X: cradle loop barrel	H: RIFT-related	T: Alanine racemase-C	F: PF02127	ECOD (1.6)
K [auth V]	PF02127	e7ddeV1	A: a/b three-layered sandwiches	X: Phosphorylase/hydrolase-like	H: Zn-dependent exopeptidases (From Topology)	T: Zn-dependent exopeptidases	F: PF02127	ECOD (1.6)
K [auth V]	PF00569	e7ddeV3	A: few secondary structure elements	X: RING/U-box-like	H: RING/U-box-like	T: RING/U-box	F: PF00569	ECOD (1.6)
L [auth X]	PF02127	e7ddeX2	A: beta barrels	X: cradle loop barrel	H: RIFT-related	T: Alanine racemase-C	F: PF02127	ECOD (1.6)
L [auth X]	PF02127	e7ddeX1	A: a/b three-layered sandwiches	X: Phosphorylase/hydrolase-like	H: Zn-dependent exopeptidases (From Topology)	T: Zn-dependent exopeptidases	F: PF02127	ECOD (1.6)
L [auth X]	PF00569	e7ddeX3	A: few secondary structure elements	X: RING/U-box-like	H: RING/U-box-like	T: RING/U-box	F: PF00569	ECOD (1.6)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B [auth C], C [auth E], D [auth G], E [auth I], A, B [auth C], C [auth E], D [auth G], E [auth I], F [auth K], G [auth M], H [auth O], I [auth Q], J [auth S], K [auth V], L [auth X]	PF00569	Zinc finger, ZZ type (ZZ)	Zinc finger, ZZ type	Zinc finger present in dystrophin, CBP/p300. ZZ in dystrophin binds calmodulin. Putative zinc finger; binding not yet shown. Four to six cysteine residues in its sequence are responsible for coordinating zinc ions, to reinforce the structure [2].	Domain
A, B [auth C], C [auth E], D [auth G], E [auth I], A, B [auth C], C [auth E], D [auth G], E [auth I], F [auth K], G [auth M], H [auth O], I [auth Q], J [auth S], K [auth V], L [auth X]	PF02127	Aminopeptidase I zinc metalloprotease (M18) (Peptidase_M18)	Aminopeptidase I zinc metalloprotease (M18)	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B [auth C], C [auth E], D [auth G], E [auth I], A, B [auth C], C [auth E], D [auth G], E [auth I], F [auth K], G [auth M], H [auth O], I [auth Q], J [auth S], K [auth V], L [auth X]	Aspartyl aminopeptidase 1,ZZ-type zinc finger-containing protein P35G2.11c,Maltose/maltodextrin-binding periplasmic protein	transporter activity carbohydrate transmembrane transporter activity transmembrane transporter activity oligosaccharide binding binding disaccharide binding carbohydrate binding maltose binding cation binding transition metal ion binding zinc ion binding ion binding metal ion binding small molecule binding transporter activity carbohydrate transmembrane transporter activity transmembrane transporter activity oligosaccharide binding binding disaccharide binding carbohydrate binding maltose binding cation binding transition metal ion binding zinc ion binding ion binding metal ion binding small molecule binding peptidase activity catalytic activity, acting on a protein hydrolase activity metallopeptidase activity aminopeptidase activity metalloaminopeptidase activity exopeptidase activity catalytic activity metalloexopeptidase activity cargo receptor activity	cellular response to stimulus cellular response to stress response to stimulus DNA damage response response to stress cellular process cell chemotaxis chemotaxis response to external stimulus cellular response to chemical stimulus taxis response to chemical cell migration cell motility cellular response to stimulus cellular response to stress response to stimulus DNA damage response response to stress cellular process cell chemotaxis chemotaxis response to external stimulus cellular response to chemical stimulus taxis response to chemical cell migration cell motility locomotion localization transport organic substance transport carbohydrate transport oligosaccharide transport disaccharide transport establishment of localization maltose transport polysaccharide localization dextrin transport macromolecule localization maltodextrin transmembrane transport polysaccharide transport response to organic substance response to disaccharide response to oxygen-containing compound detection of maltose stimulus detection of stimulus response to carbohydrate detection of chemical stimulus detection of disaccharide stimulus response to maltose detection of carbohydrate stimulus organic substance metabolic process organonitrogen compound metabolic process proteolysis metabolic process primary metabolic process protein metabolic process macromolecule metabolic process cellular biosynthetic process cellular metabolic process gene expression macromolecule biosynthetic process protein maturation protein folding biosynthetic process organic substance biosynthetic process protein localization establishment of protein localization cellular localization nitrogen compound transport protein targeting establishment of protein localization to vacuole cellular macromolecule localization establishment of localization in cell cytoplasm to vacuole targeting by the NVT pathway protein targeting to vacuole protein localization to vacuole intracellular transport establishment of protein localization to organelle protein transport protein localization to organelle vacuolar transport intracellular protein transport	ATPase dependent transmembrane transport complex protein-containing complex plasma membrane protein complex membrane plasma membrane membrane protein complex cellular anatomical entity transporter complex ATP-binding cassette (ABC) transporter complex cell periphery transmembrane transporter complex ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing maltose transport complex periplasmic space ATPase dependent transmembrane transport complex protein-containing complex plasma membrane protein complex membrane plasma membrane membrane protein complex cellular anatomical entity transporter complex ATP-binding cassette (ABC) transporter complex cell periphery transmembrane transporter complex ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing maltose transport complex periplasmic space outer membrane-bounded periplasmic space cell envelope intracellular anatomical structure cytoplasm cytosol membrane-bounded organelle storage vacuole lytic vacuole vacuole intracellular membrane-bounded organelle fungal-type vacuole intracellular organelle organelle membrane-enclosed lumen vacuolar lumen intracellular organelle lumen organelle lumen fungal-type vacuole lumen Golgi apparatus endomembrane system endosome intracellular vesicle cytoplasmic vesicle late endosome multivesicular body vesicle NVT complex

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B [auth C], C [auth E], D [auth G], E [auth I], A, B [auth C], C [auth E], D [auth G], E [auth I], F [auth K], G [auth M], H [auth O], I [auth Q], J [auth S], K [auth V], L [auth X]	IPR006061	Solute-binding family 1, conserved site	Conserved Site
A, B [auth C], C [auth E], D [auth G], E [auth I], A, B [auth C], C [auth E], D [auth G], E [auth I], F [auth K], G [auth M], H [auth O], I [auth Q], J [auth S], K [auth V], L [auth X]	IPR006060	Maltose/Cyclodextrin ABC transporter, substrate-binding protein	Family
A, B [auth C], C [auth E], D [auth G], E [auth I], A, B [auth C], C [auth E], D [auth G], E [auth I], F [auth K], G [auth M], H [auth O], I [auth Q], J [auth S], K [auth V], L [auth X]	IPR006059	Bacterial-type extracellular solute-binding protein	Family
A, B [auth C], C [auth E], D [auth G], E [auth I], A, B [auth C], C [auth E], D [auth G], E [auth I], F [auth K], G [auth M], H [auth O], I [auth Q], J [auth S], K [auth V], L [auth X]	IPR023358	Peptidase M18, domain 2	Homologous Superfamily
A, B [auth C], C [auth E], D [auth G], E [auth I], A, B [auth C], C [auth E], D [auth G], E [auth I], F [auth K], G [auth M], H [auth O], I [auth Q], J [auth S], K [auth V], L [auth X]	IPR001948	Peptidase M18	Family
A, B [auth C], C [auth E], D [auth G], E [auth I], A, B [auth C], C [auth E], D [auth G], E [auth I], F [auth K], G [auth M], H [auth O], I [auth Q], J [auth S], K [auth V], L [auth X]	IPR043145	Zinc finger, ZZ-type superfamily	Homologous Superfamily
A, B [auth C], C [auth E], D [auth G], E [auth I], A, B [auth C], C [auth E], D [auth G], E [auth I], F [auth K], G [auth M], H [auth O], I [auth Q], J [auth S], K [auth V], L [auth X]	IPR013783	Immunoglobulin-like fold	Homologous Superfamily
A, B [auth C], C [auth E], D [auth G], E [auth I], A, B [auth C], C [auth E], D [auth G], E [auth I], F [auth K], G [auth M], H [auth O], I [auth Q], J [auth S], K [auth V], L [auth X]	IPR000433	Zinc finger, ZZ-type	Domain
A, B [auth C], C [auth E], D [auth G], E [auth I], A, B [auth C], C [auth E], D [auth G], E [auth I], F [auth K], G [auth M], H [auth O], I [auth Q], J [auth S], K [auth V], L [auth X]	IPR032350	Next to BRCA1, central domain	Domain