Annotations: 7CAD

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A [auth C]	PF03459	e7cadC3	A: beta barrels	X: OB-fold	H: MOP-like (From Topology)	T: MOP-like	F: PF03459	ECOD (1.6)
A [auth C]	PF17912	e7cadC1	A: beta barrels	X: OB-fold	H: MOP-like (From Topology)	T: MOP-like	F: PF17912	ECOD (1.6)
A [auth C]	PF00005	e7cadC2	A: a/b three-layered sandwiches	X: P-loop domains-like	H: P-loop domains-related	T: P-loop containing nucleoside triphosphate hydrolases	F: PF00005	ECOD (1.6)
B [auth D]	PF03459	e7cadD2	A: beta barrels	X: OB-fold	H: MOP-like (From Topology)	T: MOP-like	F: PF03459	ECOD (1.6)
B [auth D]	PF17912	e7cadD3	A: beta barrels	X: OB-fold	H: MOP-like (From Topology)	T: MOP-like	F: PF17912	ECOD (1.6)
B [auth D]	PF00005	e7cadD1	A: a/b three-layered sandwiches	X: P-loop domains-like	H: P-loop domains-related	T: P-loop containing nucleoside triphosphate hydrolases	F: PF00005	ECOD (1.6)
C [auth A]	PF00528	e7cadA1	A: alpha bundles	X: Type II ABC exporter transmembrane domain fold	H: Type I ABC importer transmembrane domain fold (From Topology)	T: Type I ABC importer transmembrane domain fold	F: PF00528	ECOD (1.6)
D [auth B]	PF00528	e7cadB1	A: alpha bundles	X: Type II ABC exporter transmembrane domain fold	H: Type I ABC importer transmembrane domain fold (From Topology)	T: Type I ABC importer transmembrane domain fold	F: PF00528	ECOD (1.6)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A [auth C], B [auth D]	PF17912	MalK OB fold domain (OB_MalK)	MalK OB fold domain	This entry corresponds to one of two OB-fold domains found in the MalK transport protein.	Domain
A [auth C], B [auth D]	PF00005	ABC transporter (ABC_tran)	ABC transporter	ABC transporters for a large family of proteins responsible for translocation of a variety of compounds across biological membranes. ABC transporters are the largest family of proteins in many completely sequenced bacteria. ABC transporters are comp ...	ABC transporters for a large family of proteins responsible for translocation of a variety of compounds across biological membranes. ABC transporters are the largest family of proteins in many completely sequenced bacteria. ABC transporters are composed of two copies of this domain and two copies of a transmembrane domain Pfam:PF00664. These four domains may belong to a single polypeptide as in Swiss:P13569, or belong in different polypeptide chains.	Domain
C [auth A]	PF00528	Binding-protein-dependent transport system inner membrane component (BPD_transp_1)	Binding-protein-dependent transport system inner membrane component	-	Family
D [auth B]	PF00528	Binding-protein-dependent transport system inner membrane component (BPD_transp_1)	Binding-protein-dependent transport system inner membrane component	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A [auth C], B [auth D]	ABC transporter, ATP-binding protein SugC	binding adenyl ribonucleotide binding nucleotide binding purine ribonucleotide binding purine ribonucleoside triphosphate binding nucleoside phosphate binding ion binding purine nucleotide binding organic cyclic compound binding anion binding adenyl nucleotide binding ATP binding heterocyclic compound binding carbohydrate derivative binding binding adenyl ribonucleotide binding nucleotide binding purine ribonucleotide binding purine ribonucleoside triphosphate binding nucleoside phosphate binding ion binding purine nucleotide binding organic cyclic compound binding anion binding adenyl nucleotide binding ATP binding heterocyclic compound binding carbohydrate derivative binding ribonucleotide binding small molecule binding ABC-type transporter activity active transmembrane transporter activity primary active transmembrane transporter activity ATPase-coupled transmembrane transporter activity transporter activity transmembrane transporter activity ATP-dependent activity pyrophosphatase activity ATP hydrolysis activity ribonucleoside triphosphate phosphatase activity hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides hydrolase activity hydrolase activity, acting on acid anhydrides catalytic activity	localization transport organic substance transport carbohydrate transport establishment of localization	ATPase dependent transmembrane transport complex protein-containing complex plasma membrane protein complex membrane plasma membrane membrane protein complex cellular anatomical entity transporter complex ATP-binding cassette (ABC) transporter complex cell periphery transmembrane transporter complex
C [auth A]	ABC sugar transporter, permease component	-	transmembrane transport localization transport cellular process establishment of localization	cell periphery plasma membrane membrane cellular anatomical entity
D [auth B]	ABC transporter, permease protein SugB	-	transmembrane transport localization transport cellular process establishment of localization	cell periphery plasma membrane membrane cellular anatomical entity

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A [auth C], B [auth D]	IPR017871	ABC transporter-like, conserved site	Conserved Site
A [auth C], B [auth D]	IPR047641	ABC transporter, ATP-binding protein MalK/UgpC-like	Family
A [auth C], B [auth D]	IPR003439	ABC transporter-like, ATP-binding domain	Domain
A [auth C], B [auth D]	IPR003593	AAA+ ATPase domain	Domain
A [auth C], B [auth D]	IPR012340	Nucleic acid-binding, OB-fold	Homologous Superfamily
A [auth C], B [auth D]	IPR008995	Molybdate/tungstate binding, C-terminal	Homologous Superfamily
A [auth C], B [auth D]	IPR015855	ABC transporter, maltose/maltodextrin import, MalK-like	Domain
A [auth C], B [auth D]	IPR040582	MalK-like, OB fold domain	Domain
A [auth C], B [auth D]	IPR027417	P-loop containing nucleoside triphosphate hydrolase	Homologous Superfamily
C [auth A]	IPR000515	ABC transporter type 1, transmembrane domain MetI-like	Domain
C [auth A]	IPR035906	MetI-like superfamily	Homologous Superfamily
D [auth B]	IPR000515	ABC transporter type 1, transmembrane domain MetI-like	Domain
D [auth B]	IPR035906	MetI-like superfamily	Homologous Superfamily

Membrane Protein Annotation: OPM OPM Database Homepage

Chains	External Link	Type	Class	Superfamily	Family
C [auth A], D [auth B]	OPM	Transmembrane	Alpha-helical polytopic	ABC transporters	Binding-protein-dependent transport system

Membrane Protein Annotation: PDBTM PDBTM Database Homepage

Chains	External Link	Comment
C [auth A], D [auth B]	PDBTM	Annotated as membrane protein by PDBTM

Membrane Protein Annotation: MemProtMD MemProtMD Database Homepage

Chains	External Link	Comment
C [auth A], D [auth B]	MemProtMD	Annotated as membrane protein by MemProtMD

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.