Annotations: 6ZNK

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	F_UNCLASSIFIED	e6znkA1	A: a/b three-layered sandwiches	X: Isocitrate/Isopropylmalate dehydrogenase-like (From Topology)	H: Isocitrate/Isopropylmalate dehydrogenase-like (From Topology)	T: Isocitrate/Isopropylmalate dehydrogenase-like	F: F_UNCLASSIFIED	ECOD (1.6)
B	F_UNCLASSIFIED	e6znkB1	A: a/b three-layered sandwiches	X: Isocitrate/Isopropylmalate dehydrogenase-like (From Topology)	H: Isocitrate/Isopropylmalate dehydrogenase-like (From Topology)	T: Isocitrate/Isopropylmalate dehydrogenase-like	F: F_UNCLASSIFIED	ECOD (1.6)
C [auth D]	PF01515	e6znkD2	A: a/b three-layered sandwiches	X: Isocitrate/Isopropylmalate dehydrogenase-like (From Topology)	H: Isocitrate/Isopropylmalate dehydrogenase-like (From Topology)	T: Isocitrate/Isopropylmalate dehydrogenase-like	F: PF01515	ECOD (1.6)
D [auth F]	F_UNCLASSIFIED	e6znkF2	A: a/b three-layered sandwiches	X: Isocitrate/Isopropylmalate dehydrogenase-like (From Topology)	H: Isocitrate/Isopropylmalate dehydrogenase-like (From Topology)	T: Isocitrate/Isopropylmalate dehydrogenase-like	F: F_UNCLASSIFIED	ECOD (1.6)
E	F_UNCLASSIFIED	e6znkE2	A: a/b three-layered sandwiches	X: Isocitrate/Isopropylmalate dehydrogenase-like (From Topology)	H: Isocitrate/Isopropylmalate dehydrogenase-like (From Topology)	T: Isocitrate/Isopropylmalate dehydrogenase-like	F: F_UNCLASSIFIED	ECOD (1.6)
F [auth C]	F_UNCLASSIFIED	e6znkC2	A: a/b three-layered sandwiches	X: Isocitrate/Isopropylmalate dehydrogenase-like (From Topology)	H: Isocitrate/Isopropylmalate dehydrogenase-like (From Topology)	T: Isocitrate/Isopropylmalate dehydrogenase-like	F: F_UNCLASSIFIED	ECOD (1.6)
G	F_UNCLASSIFIED	e6znkG2	A: a/b three-layered sandwiches	X: Isocitrate/Isopropylmalate dehydrogenase-like (From Topology)	H: Isocitrate/Isopropylmalate dehydrogenase-like (From Topology)	T: Isocitrate/Isopropylmalate dehydrogenase-like	F: F_UNCLASSIFIED	ECOD (1.6)
H	F_UNCLASSIFIED	e6znkH1	A: a/b three-layered sandwiches	X: Isocitrate/Isopropylmalate dehydrogenase-like (From Topology)	H: Isocitrate/Isopropylmalate dehydrogenase-like (From Topology)	T: Isocitrate/Isopropylmalate dehydrogenase-like	F: F_UNCLASSIFIED	ECOD (1.6)
I	F_UNCLASSIFIED	e6znkI1	A: a/b three-layered sandwiches	X: Isocitrate/Isopropylmalate dehydrogenase-like (From Topology)	H: Isocitrate/Isopropylmalate dehydrogenase-like (From Topology)	T: Isocitrate/Isopropylmalate dehydrogenase-like	F: F_UNCLASSIFIED	ECOD (1.6)
J	F_UNCLASSIFIED	e6znkJ2	A: a/b three-layered sandwiches	X: Isocitrate/Isopropylmalate dehydrogenase-like (From Topology)	H: Isocitrate/Isopropylmalate dehydrogenase-like (From Topology)	T: Isocitrate/Isopropylmalate dehydrogenase-like	F: F_UNCLASSIFIED	ECOD (1.6)
K	F_UNCLASSIFIED	e6znkK1	A: a/b three-layered sandwiches	X: Isocitrate/Isopropylmalate dehydrogenase-like (From Topology)	H: Isocitrate/Isopropylmalate dehydrogenase-like (From Topology)	T: Isocitrate/Isopropylmalate dehydrogenase-like	F: F_UNCLASSIFIED	ECOD (1.6)
L	F_UNCLASSIFIED	e6znkL2	A: a/b three-layered sandwiches	X: Isocitrate/Isopropylmalate dehydrogenase-like (From Topology)	H: Isocitrate/Isopropylmalate dehydrogenase-like (From Topology)	T: Isocitrate/Isopropylmalate dehydrogenase-like	F: F_UNCLASSIFIED	ECOD (1.6)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B, C [auth D], D [auth F], E, A, B, C [auth D], D [auth F], E, F [auth C], G, H, I, J, K, L	PF01515	Phosphate acetyl/butaryl transferase (PTA_PTB)	Phosphate acetyl/butaryl transferase	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B, C [auth D], D [auth F], E, A, B, C [auth D], D [auth F], E, F [auth C], G, H, I, J, K, L	Malate dehydrogenase	oxidoreductase activity malate dehydrogenase (decarboxylating) (NADP+) activity oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor oxidoreductase activity, acting on CH-OH group of donors malic enzyme activity malate dehydrogenase activity catalytic activity oxaloacetate decarboxylase activity carboxy-lyase activity lyase activity carbon-carbon lyase activity NAD binding binding nucleoside phosphate binding oxidoreductase activity malate dehydrogenase (decarboxylating) (NADP+) activity oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor oxidoreductase activity, acting on CH-OH group of donors malic enzyme activity malate dehydrogenase activity catalytic activity oxaloacetate decarboxylase activity carboxy-lyase activity lyase activity carbon-carbon lyase activity NAD binding binding nucleoside phosphate binding purine nucleotide binding organic cyclic compound binding adenyl nucleotide binding nucleotide binding heterocyclic compound binding small molecule binding acyltransferase activity transferase activity cation binding ion binding metal ion binding	-	-

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B, C [auth D], D [auth F], E, A, B, C [auth D], D [auth F], E, F [auth C], G, H, I, J, K, L	IPR012302	Malic enzyme, NAD-binding	Domain
A, B, C [auth D], D [auth F], E, A, B, C [auth D], D [auth F], E, F [auth C], G, H, I, J, K, L	IPR012301	Malic enzyme, N-terminal domain	Domain
A, B, C [auth D], D [auth F], E, A, B, C [auth D], D [auth F], E, F [auth C], G, H, I, J, K, L	IPR046346	Aminoacid dehydrogenase-like, N-terminal domain superfamily	Homologous Superfamily
A, B, C [auth D], D [auth F], E, A, B, C [auth D], D [auth F], E, F [auth C], G, H, I, J, K, L	IPR002505	Phosphate acetyl/butaryl transferase	Domain
A, B, C [auth D], D [auth F], E, A, B, C [auth D], D [auth F], E, F [auth C], G, H, I, J, K, L	IPR042113	Phosphate acetyltransferase, domain 1	Homologous Superfamily
A, B, C [auth D], D [auth F], E, A, B, C [auth D], D [auth F], E, F [auth C], G, H, I, J, K, L	IPR045213	Malic enzyme, NAD-binding domain, bacterial type	Domain
A, B, C [auth D], D [auth F], E, A, B, C [auth D], D [auth F], E, F [auth C], G, H, I, J, K, L	IPR036291	NAD(P)-binding domain superfamily	Homologous Superfamily
A, B, C [auth D], D [auth F], E, A, B, C [auth D], D [auth F], E, F [auth C], G, H, I, J, K, L	IPR042112	Phosphate acetyltransferase, domain 2	Homologous Superfamily
A, B, C [auth D], D [auth F], E, A, B, C [auth D], D [auth F], E, F [auth C], G, H, I, J, K, L	IPR037062	Malic enzyme, N-terminal domain superfamily	Homologous Superfamily

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.