6YNX

Cryo-EM structure of Tetrahymena thermophila mitochondrial ATP synthase - Fo-subcomplex

External Resource: Annotation

Domain Annotation: ECOD Classification
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification
Membrane Protein Annotation: mpstruc

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
IA [auth Q]	F_UNCLASSIFIED	e6ynxQ1	A: alpha bundles	X: ACP-like	H: Acyl-carrier protein (ACP) (From Topology)	T: Acyl-carrier protein (ACP)	F: F_UNCLASSIFIED	ECOD (1.6)
P [auth q]	F_UNCLASSIFIED	e6ynxq1	A: alpha bundles	X: ACP-like	H: Acyl-carrier protein (ACP) (From Topology)	T: Acyl-carrier protein (ACP)	F: F_UNCLASSIFIED	ECOD (1.6)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
LA [auth E], S [auth e]	PF07992	Pyridine nucleotide-disulphide oxidoreductase (Pyr_redox_2)	Pyridine nucleotide-disulphide oxidoreductase	This family includes both class I and class II oxidoreductases and also NADH oxidases and peroxidases. This domain is actually a small NADH binding domain within a larger FAD binding domain.	Domain
OA [auth t]	PF00561	alpha/beta hydrolase fold (Abhydrolase_1)	alpha/beta hydrolase fold	This catalytic domain is found in a very wide range of enzymes.	Domain
C [auth d], V [auth D]	PF05873	ATP synthase D chain, mitochondrial (ATP5H) (Mt_ATP-synt_D)	ATP synthase D chain, mitochondrial (ATP5H)	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A [auth a], T [auth A]	subunit a	-	-	membrane-bounded organelle intracellular organelle intracellular anatomical structure mitochondrion organelle cytoplasm cellular anatomical entity intracellular membrane-bounded organelle membrane
CA [auth J], J [auth j]	ATPTT5	-	-	-
DA [auth L], K [auth l]	ATPTT6	-	-	-
EA [auth M], L [auth m]	ATPTT7	-	-	-
FA [auth N], M [auth n]	ATPTT8	-	-	-
GA [auth O], N [auth o]	ATPTT9	-	-	-
HA [auth P], O [auth p]	ATPTT10	-	-	-
IA [auth Q], P [auth q]	ATPTT11	-	-	-
JA [auth R], Q [auth r]	ATPTT12	-	-	-
KA [auth S], R [auth s]	ATPTT13	-	-	-
LA [auth E], S [auth e]	ATPTT1	oxidoreductase activity catalytic activity	-	-
B [auth b], U [auth B]	subunit b	-	-	membrane cellular anatomical entity
MA [auth i1], NA [auth i2]	Inhibitor of F1 (IF1)	-	-	-
OA [auth t]	ATPTT2	hydrolase activity catalytic activity	-	-
C [auth d], V [auth D]	subunit d	monoatomic cation transmembrane transporter activity proton transmembrane transporter activity inorganic molecular entity transmembrane transporter activity inorganic cation transmembrane transporter activity monoatomic ion transmembrane transporter activity transporter activity transmembrane transporter activity	ribose phosphate metabolic process ATP metabolic process ATP biosynthetic process nucleotide biosynthetic process organonitrogen compound biosynthetic process carbohydrate derivative metabolic process purine ribonucleotide biosynthetic process purine ribonucleoside triphosphate biosynthetic process proton motive force-driven ATP synthesis nucleobase-containing compound metabolic process ribonucleotide biosynthetic process purine nucleotide metabolic process organic substance metabolic process ribonucleotide metabolic process purine nucleoside triphosphate biosynthetic process ribose phosphate metabolic process ATP metabolic process ATP biosynthetic process nucleotide biosynthetic process organonitrogen compound biosynthetic process carbohydrate derivative metabolic process purine ribonucleotide biosynthetic process purine ribonucleoside triphosphate biosynthetic process proton motive force-driven ATP synthesis nucleobase-containing compound metabolic process ribonucleotide biosynthetic process purine nucleotide metabolic process organic substance metabolic process ribonucleotide metabolic process purine nucleoside triphosphate biosynthetic process nucleobase-containing small molecule metabolic process purine-containing compound biosynthetic process purine ribonucleoside triphosphate metabolic process phosphate-containing compound metabolic process organic substance biosynthetic process small molecule metabolic process phosphorus metabolic process ribose phosphate biosynthetic process ribonucleoside triphosphate metabolic process nucleoside phosphate metabolic process carbohydrate derivative biosynthetic process purine nucleoside triphosphate metabolic process organonitrogen compound metabolic process nucleoside triphosphate biosynthetic process cellular metabolic process primary metabolic process nucleotide metabolic process nucleobase-containing compound biosynthetic process ribonucleoside triphosphate biosynthetic process purine-containing compound metabolic process organic cyclic compound metabolic process biosynthetic process organophosphate metabolic process organophosphate biosynthetic process organic cyclic compound biosynthetic process nucleoside phosphate biosynthetic process metabolic process cellular process nucleoside triphosphate metabolic process purine ribonucleotide metabolic process purine nucleotide biosynthetic process	membrane-bounded organelle protein-containing complex ATPase complex intracellular anatomical structure mitochondrial membrane organelle inner membrane mitochondrion membrane protein complex intracellular organelle organelle envelope proton-transporting two-sector ATPase complex proton-transporting ATP synthase complex, coupling factor F(o) mitochondrial proton-transporting ATP synthase complex, coupling factor F(o) mitochondrial protein-containing complex membrane-bounded organelle protein-containing complex ATPase complex intracellular anatomical structure mitochondrial membrane organelle inner membrane mitochondrion membrane protein complex intracellular organelle organelle envelope proton-transporting two-sector ATPase complex proton-transporting ATP synthase complex, coupling factor F(o) mitochondrial proton-transporting ATP synthase complex, coupling factor F(o) mitochondrial protein-containing complex catalytic complex membrane proton-transporting ATP synthase complex cellular anatomical entity intracellular membrane-bounded organelle proton-transporting two-sector ATPase complex, proton-transporting domain mitochondrial inner membrane mitochondrial proton-transporting ATP synthase complex inner mitochondrial membrane protein complex organelle mitochondrial envelope cytoplasm organelle membrane
D [auth f], W [auth F]	subunit f	-	-	-
E [auth i], X [auth I]	subunit i/j	-	-	membrane cellular anatomical entity
F [auth k], Y [auth K]	subunit k	-	-	membrane cellular anatomical entity
G [auth c], Z [auth C]	subunit 8	-	-	membrane-bounded organelle intracellular organelle intracellular anatomical structure mitochondrion organelle cytoplasm cellular anatomical entity intracellular membrane-bounded organelle membrane
AA [auth G], H [auth g]	ATPTT3	-	-	membrane cellular anatomical entity
BA [auth H], I [auth h]	ATPTT4	-	-	-

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
IA [auth Q], P [auth q]	IPR009081	Phosphopantetheine binding ACP domain	Domain
IA [auth Q], P [auth q]	IPR036736	ACP-like superfamily	Homologous Superfamily
LA [auth E], S [auth e]	IPR015904	Sulphide quinone-reductase	Family
LA [auth E], S [auth e]	IPR023753	FAD/NAD(P)-binding domain	Domain
LA [auth E], S [auth e]	IPR036188	FAD/NAD(P)-binding domain superfamily	Homologous Superfamily
OA [auth t]	IPR000073	Alpha/beta hydrolase fold-1	Domain
OA [auth t]	IPR029058	Alpha/Beta hydrolase fold	Homologous Superfamily
C [auth d], V [auth D]	IPR036228	ATP synthase, F0 complex, subunit D superfamily, mitochondrial	Homologous Superfamily
C [auth d], V [auth D]	IPR008689	ATP synthase, F0 complex, subunit D, mitochondrial	Family

Membrane Protein Annotation: mpstruc mpstruc Database Homepage

Chains	Resource Link	Group	Subgroup	Protein
A [auth a], AA [auth G], B [auth b], E [auth i], F [auth k] A [auth a], AA [auth G], B [auth b], E [auth i], F [auth k], G [auth c], H [auth g], T [auth A], U [auth B], X [auth I], Y [auth K], Z [auth C]	mpstruc	TRANSMEMBRANE PROTEINS: ALPHA-HELICAL	F-type ATPase	F₁F_o type III ATP synthase (composite structure, dimeric)