6YNW

Cryo-EM structure of Tetrahymena thermophila mitochondrial ATP synthase - central stalk/cring

External Resource: Annotation

Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification
Membrane Protein Annotation: OPM
Membrane Protein Annotation: PDBTM
Membrane Protein Annotation: MemProtMD
Membrane Protein Annotation: mpstruc

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
K [auth g]	SCOP2B Superfamily	ATP synthase gamma subunit-like	8099238	3000451	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
G [auth J]	PF00137	e6ynwJ1	A: extended segments	X: F1F0 ATP synthase subunit C (From Topology)	H: F1F0 ATP synthase subunit C (From Topology)	T: F1F0 ATP synthase subunit C	F: PF00137	ECOD (1.6)
A [auth P]	PF00137	e6ynwP1	A: extended segments	X: F1F0 ATP synthase subunit C (From Topology)	H: F1F0 ATP synthase subunit C (From Topology)	T: F1F0 ATP synthase subunit C	F: PF00137	ECOD (1.6)
B [auth O]	PF00137	e6ynwO1	A: extended segments	X: F1F0 ATP synthase subunit C (From Topology)	H: F1F0 ATP synthase subunit C (From Topology)	T: F1F0 ATP synthase subunit C	F: PF00137	ECOD (1.6)
C [auth N]	PF00137	e6ynwN1	A: extended segments	X: F1F0 ATP synthase subunit C (From Topology)	H: F1F0 ATP synthase subunit C (From Topology)	T: F1F0 ATP synthase subunit C	F: PF00137	ECOD (1.6)
D [auth M]	PF00137	e6ynwM1	A: extended segments	X: F1F0 ATP synthase subunit C (From Topology)	H: F1F0 ATP synthase subunit C (From Topology)	T: F1F0 ATP synthase subunit C	F: PF00137	ECOD (1.6)
E [auth L]	PF00137	e6ynwL1	A: extended segments	X: F1F0 ATP synthase subunit C (From Topology)	H: F1F0 ATP synthase subunit C (From Topology)	T: F1F0 ATP synthase subunit C	F: PF00137	ECOD (1.6)
F [auth K]	PF00137	e6ynwK1	A: extended segments	X: F1F0 ATP synthase subunit C (From Topology)	H: F1F0 ATP synthase subunit C (From Topology)	T: F1F0 ATP synthase subunit C	F: PF00137	ECOD (1.6)
H [auth I]	PF00137	e6ynwI1	A: extended segments	X: F1F0 ATP synthase subunit C (From Topology)	H: F1F0 ATP synthase subunit C (From Topology)	T: F1F0 ATP synthase subunit C	F: PF00137	ECOD (1.6)
I [auth H]	PF00137	e6ynwH1	A: extended segments	X: F1F0 ATP synthase subunit C (From Topology)	H: F1F0 ATP synthase subunit C (From Topology)	T: F1F0 ATP synthase subunit C	F: PF00137	ECOD (1.6)
J [auth Q]	PF00137	e6ynwQ1	A: extended segments	X: F1F0 ATP synthase subunit C (From Topology)	H: F1F0 ATP synthase subunit C (From Topology)	T: F1F0 ATP synthase subunit C	F: PF00137	ECOD (1.6)
K [auth g]	PF00231	e6ynwg1	A: a/b three-layered sandwiches	X: ATP synthase (F1-ATPase), gamma subunit (From Topology)	H: ATP synthase (F1-ATPase), gamma subunit (From Topology)	T: ATP synthase (F1-ATPase), gamma subunit	F: PF00231	ECOD (1.6)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A [auth P], B [auth O], C [auth N], D [auth M], E [auth L], A [auth P], B [auth O], C [auth N], D [auth M], E [auth L], F [auth K], G [auth J], H [auth I], I [auth H], J [auth Q]	PF00137	ATP synthase subunit C (ATP-synt_C)	ATP synthase subunit C	-	Family
K [auth g]	PF00231	ATP synthase (ATP-synt)	ATP synthase	-	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A [auth P], B [auth O], C [auth N], D [auth M], E [auth L], A [auth P], B [auth O], C [auth N], D [auth M], E [auth L], F [auth K], G [auth J], H [auth I], I [auth H], J [auth Q]	subunit c	hydrolase activity catalytic activity monoatomic cation transmembrane transporter activity proton transmembrane transporter activity inorganic molecular entity transmembrane transporter activity inorganic cation transmembrane transporter activity monoatomic ion transmembrane transporter activity transporter activity transmembrane transporter activity binding lipid binding	-	membrane-bounded organelle intracellular organelle intracellular anatomical structure mitochondrion organelle cytoplasm cellular anatomical entity intracellular membrane-bounded organelle protein-containing complex ATPase complex catalytic complex membrane proton-transporting ATP synthase complex membrane protein complex membrane-bounded organelle intracellular organelle intracellular anatomical structure mitochondrion organelle cytoplasm cellular anatomical entity intracellular membrane-bounded organelle protein-containing complex ATPase complex catalytic complex membrane proton-transporting ATP synthase complex membrane protein complex proton-transporting two-sector ATPase complex, proton-transporting domain proton-transporting two-sector ATPase complex proton-transporting ATP synthase complex, coupling factor F(o)
K [auth g]	subunit gamma	monoatomic cation transmembrane transporter activity proton transmembrane transporter activity monoatomic ion channel activity proton channel activity proton-transporting ATP synthase activity, rotational mechanism monoatomic cation channel activity passive transmembrane transporter activity inorganic molecular entity transmembrane transporter activity inorganic cation transmembrane transporter activity channel activity monoatomic ion transmembrane transporter activity transporter activity transmembrane transporter activity catalytic activity monoatomic cation transmembrane transporter activity proton transmembrane transporter activity monoatomic ion channel activity proton channel activity proton-transporting ATP synthase activity, rotational mechanism monoatomic cation channel activity passive transmembrane transporter activity inorganic molecular entity transmembrane transporter activity inorganic cation transmembrane transporter activity channel activity monoatomic ion transmembrane transporter activity transporter activity transmembrane transporter activity catalytic activity ligase activity	-	membrane-bounded organelle mitochondrial membrane intracellular anatomical structure organelle inner membrane mitochondrion membrane cellular anatomical entity intracellular membrane-bounded organelle mitochondrial inner membrane intracellular organelle organelle envelope mitochondrial envelope organelle cytoplasm membrane-bounded organelle mitochondrial membrane intracellular anatomical structure organelle inner membrane mitochondrion membrane cellular anatomical entity intracellular membrane-bounded organelle mitochondrial inner membrane intracellular organelle organelle envelope mitochondrial envelope organelle cytoplasm organelle membrane protein-containing complex ATPase complex catalytic complex proton-transporting ATP synthase complex membrane protein complex proton-transporting two-sector ATPase complex proton-transporting two-sector ATPase complex, catalytic domain proton-transporting ATP synthase complex, catalytic core F(1)
L [auth d]	subunit delta	-	-	-
M [auth e]	subunit epsilon	-	-	-

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A [auth P], B [auth O], C [auth N], D [auth M], E [auth L], A [auth P], B [auth O], C [auth N], D [auth M], E [auth L], F [auth K], G [auth J], H [auth I], I [auth H], J [auth Q]	IPR035921	F/V-ATP synthase subunit C superfamily	Homologous Superfamily
A [auth P], B [auth O], C [auth N], D [auth M], E [auth L], A [auth P], B [auth O], C [auth N], D [auth M], E [auth L], F [auth K], G [auth J], H [auth I], I [auth H], J [auth Q]	IPR038662	F1F0 ATP synthase subunit C superfamily	Homologous Superfamily
A [auth P], B [auth O], C [auth N], D [auth M], E [auth L], A [auth P], B [auth O], C [auth N], D [auth M], E [auth L], F [auth K], G [auth J], H [auth I], I [auth H], J [auth Q]	IPR020537	ATP synthase, F0 complex, subunit C, DCCD-binding site	Binding Site
A [auth P], B [auth O], C [auth N], D [auth M], E [auth L], A [auth P], B [auth O], C [auth N], D [auth M], E [auth L], F [auth K], G [auth J], H [auth I], I [auth H], J [auth Q]	IPR002379	V-ATPase proteolipid subunit C-like domain	Domain
K [auth g]	IPR000131	ATP synthase, F1 complex, gamma subunit	Family
K [auth g]	IPR035968	ATP synthase, F1 complex, gamma subunit superfamily	Homologous Superfamily

Membrane Protein Annotation: OPM OPM Database Homepage

Chains	External Link	Type	Class	Superfamily	Family
A [auth P], B [auth O], C [auth N], D [auth M], E [auth L] A [auth P], B [auth O], C [auth N], D [auth M], E [auth L], F [auth K], G [auth J], H [auth I], I [auth H], J [auth Q], K [auth g]	OPM	Transmembrane	Alpha-helical polytopic	Proton or Sodium translocating F-type, V-type and A-type ATPases	V-type and F-type ATPases

Membrane Protein Annotation: PDBTM PDBTM Database Homepage

Chains	External Link	Comment
A [auth P], B [auth O], C [auth N], D [auth M], E [auth L] A [auth P], B [auth O], C [auth N], D [auth M], E [auth L], F [auth K], G [auth J], H [auth I], I [auth H], J [auth Q], K [auth g]	PDBTM	Annotated as membrane protein by PDBTM

Membrane Protein Annotation: MemProtMD MemProtMD Database Homepage

Chains	External Link	Comment
A [auth P], B [auth O], C [auth N], D [auth M], E [auth L] A [auth P], B [auth O], C [auth N], D [auth M], E [auth L], F [auth K], G [auth J], H [auth I], I [auth H], J [auth Q], K [auth g]	MemProtMD	Annotated as membrane protein by MemProtMD

Membrane Protein Annotation: mpstruc mpstruc Database Homepage

Chains	Resource Link	Group	Subgroup	Protein
A [auth P], B [auth O], C [auth N], D [auth M], E [auth L] A [auth P], B [auth O], C [auth N], D [auth M], E [auth L], F [auth K], G [auth J], H [auth I], I [auth H], J [auth Q], K [auth g]	mpstruc	TRANSMEMBRANE PROTEINS: ALPHA-HELICAL	F-type ATPase	F₁F_o type III ATP synthase (composite structure, dimeric)

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.