Annotations: 6YCY

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
B	d6ycyb_	All alpha proteins	EF Hand-like	EF-hand	automated matches	automated matches	(Plasmodium falciparum 3D7 ) [TaxId: 36329 ],	SCOPe (2.08)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	F_UNCLASSIFIED	e6ycyA2	A: beta barrels	X: SH3	H: SH3	T: SH3	F: F_UNCLASSIFIED	ECOD (1.6)
A	F_UNCLASSIFIED	e6ycyA3	A: alpha bundles	X: Myosin VI lever arm (From Topology)	H: Myosin VI lever arm (From Topology)	T: Myosin VI lever arm	F: F_UNCLASSIFIED	ECOD (1.6)
A	PF00063	e6ycyA1	A: a/b three-layered sandwiches	X: P-loop domains-like	H: P-loop domains-related	T: P-loop containing nucleoside triphosphate hydrolases	F: PF00063	ECOD (1.6)
B	PF13405	e6ycyB1	A: alpha arrays	X: EF-hand	H: EF-hand-related	T: EF-hand	F: PF13405	ECOD (1.6)
B	PF21550	e6ycyB2	A: alpha arrays	X: EF-hand	H: EF-hand-related	T: EF-hand	F: PF21550	ECOD (1.6)
C [auth E]	F_UNCLASSIFIED	e6ycyE2	A: alpha arrays	X: EF-hand	H: EF-hand-related	T: EF-hand	F: F_UNCLASSIFIED	ECOD (1.6)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A	PF00063	Myosin head (motor domain) (Myosin_head)	Myosin head (motor domain)	-	Domain
B	PF13405	EF-hand domain (EF-hand_6)	EF-hand domain	-	Domain
B	PF21550	Myosin A tail domain interacting protein, N-terminal (MTIP_N)	Myosin A tail domain interacting protein, N-terminal	This domain is found at the N-terminal end of Myosin A tail domain interacting protein from Plasmodium falciparum (MTIP) and in similar eukaryotic sequences. MTIP is one of the proteins that empower host cell invasion. This domain adopts an EF hand c ...	This domain is found at the N-terminal end of Myosin A tail domain interacting protein from Plasmodium falciparum (MTIP) and in similar eukaryotic sequences. MTIP is one of the proteins that empower host cell invasion. This domain adopts an EF hand configuration [1-5].	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A	Myosin-A	binding adenyl ribonucleotide binding nucleotide binding purine ribonucleotide binding purine ribonucleoside triphosphate binding nucleoside phosphate binding ion binding purine nucleotide binding organic cyclic compound binding anion binding adenyl nucleotide binding ATP binding heterocyclic compound binding carbohydrate derivative binding binding adenyl ribonucleotide binding nucleotide binding purine ribonucleotide binding purine ribonucleoside triphosphate binding nucleoside phosphate binding ion binding purine nucleotide binding organic cyclic compound binding anion binding adenyl nucleotide binding ATP binding heterocyclic compound binding carbohydrate derivative binding ribonucleotide binding small molecule binding cytoskeletal protein binding actin binding protein-containing complex binding protein binding actin filament binding cytoskeletal motor activity microfilament motor activity ATP-dependent activity	vesicle transport along actin filament vesicle cytoskeletal trafficking vesicle localization establishment of organelle localization cellular localization transport establishment of vesicle localization intracellular transport actin filament-based movement establishment of localization localization organelle localization establishment of localization in cell actin filament-based process vesicle transport along actin filament vesicle cytoskeletal trafficking vesicle localization establishment of organelle localization cellular localization transport establishment of vesicle localization intracellular transport actin filament-based movement establishment of localization localization organelle localization establishment of localization in cell actin filament-based process cytoskeleton-dependent intracellular transport cellular process actin filament-based transport cellular component organization organelle organization actin cytoskeleton organization actin filament organization cellular component organization or biogenesis supramolecular fiber organization cytoskeleton organization	membrane cellular anatomical entity membrane-bounded organelle organelle vesicle intracellular organelle intracellular anatomical structure cytoskeleton intracellular non-membrane-bounded organelle actin cytoskeleton non-membrane-bounded organelle cell periphery plasma membrane pellicle membrane cellular anatomical entity membrane-bounded organelle organelle vesicle intracellular organelle intracellular anatomical structure cytoskeleton intracellular non-membrane-bounded organelle actin cytoskeleton non-membrane-bounded organelle cell periphery plasma membrane pellicle inner membrane pellicle complex cytoplasm protein-containing complex myosin complex glideosome
B	Myosin A tail domain interacting protein	cation binding ion binding binding calcium ion binding metal ion binding small molecule binding myosin heavy chain binding cytoskeletal protein binding protein binding myosin binding	assembly of actomyosin apparatus involved in cytokinesis mitotic actomyosin contractile ring assembly cytoskeleton-dependent cytokinesis mitotic cytokinetic process actomyosin contractile ring assembly mitotic cytokinesis mitotic cell cycle cellular component organization cellular component biogenesis cellular component assembly cortical actin cytoskeleton organization actin filament-based process cellular component organization or biogenesis cell cycle assembly of actomyosin apparatus involved in cytokinesis mitotic actomyosin contractile ring assembly cytoskeleton-dependent cytokinesis mitotic cytokinetic process actomyosin contractile ring assembly mitotic cytokinesis mitotic cell cycle cellular component organization cellular component biogenesis cellular component assembly cortical actin cytoskeleton organization actin filament-based process cellular component organization or biogenesis cell cycle cell cycle process assembly of actomyosin apparatus involved in mitotic cytokinesis actin cytoskeleton organization actomyosin structure organization cortical cytoskeleton organization cytokinesis organelle organization mitotic cell cycle process cytokinetic process actomyosin contractile ring organization cellular process cell division cytoskeleton organization	protein-containing complex intracellular anatomical structure cellular anatomical entity actin cytoskeleton myosin complex intracellular organelle cytoskeleton organelle intracellular non-membrane-bounded organelle myosin II complex non-membrane-bounded organelle pellicle inner membrane pellicle complex glideosome
C [auth E]	Myosin essential light chain ELC	-	-	-

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A	IPR036961	Kinesin motor domain superfamily	Homologous Superfamily
A	IPR036044	Class XIV myosin, motor domain	Domain
A	IPR001609	Myosin head, motor domain	Domain
A	IPR027417	P-loop containing nucleoside triphosphate hydrolase	Homologous Superfamily
B	IPR049007	Myosin A tail domain interacting protein, EF-hand domain	Domain
B	IPR002048	EF-hand domain	Domain
B	IPR011992	EF-hand domain pair	Homologous Superfamily
C [auth E]	IPR011992	EF-hand domain pair	Homologous Superfamily

Protein Modification Annotation

Modified Residue(s)
Chain	Residue(s)	Description
A	SEP	Parent Component: SER RESID: AA0037 PSI-MOD : O-phospho-L-serine MOD:00046

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.