Annotations: 6Y7F

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B	PF01151	GNS1/SUR4 family (ELO)	GNS1/SUR4 family	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B	Elongation of very long chain fatty acids protein 7	fatty acid elongase activity acyltransferase activity acyltransferase activity, transferring groups other than amino-acyl groups transferase activity catalytic activity	nucleoside bisphosphate metabolic process ribonucleoside bisphosphate biosynthetic process nucleotide biosynthetic process organonitrogen compound biosynthetic process carbohydrate derivative metabolic process purine ribonucleotide biosynthetic process nucleobase-containing compound metabolic process ribonucleotide biosynthetic process organic substance biosynthetic process phosphate-containing compound metabolic process small molecule metabolic process sulfur compound metabolic process thioester metabolic process fatty-acyl-CoA metabolic process nucleoside bisphosphate metabolic process ribonucleoside bisphosphate biosynthetic process nucleotide biosynthetic process organonitrogen compound biosynthetic process carbohydrate derivative metabolic process purine ribonucleotide biosynthetic process nucleobase-containing compound metabolic process ribonucleotide biosynthetic process organic substance biosynthetic process phosphate-containing compound metabolic process small molecule metabolic process sulfur compound metabolic process thioester metabolic process fatty-acyl-CoA metabolic process phosphorus metabolic process ribose phosphate biosynthetic process nucleoside phosphate metabolic process cellular metabolic process primary metabolic process amide biosynthetic process long-chain fatty-acyl-CoA metabolic process nucleotide metabolic process organic cyclic compound metabolic process sulfur compound biosynthetic process biosynthetic process organophosphate biosynthetic process organic cyclic compound biosynthetic process nucleoside phosphate biosynthetic process metabolic process purine ribonucleotide metabolic process purine nucleotide biosynthetic process ribose phosphate metabolic process purine nucleoside bisphosphate metabolic process ribonucleoside bisphosphate metabolic process thioester biosynthetic process cellular biosynthetic process lipid biosynthetic process fatty-acyl-CoA biosynthetic process organic substance metabolic process purine nucleotide metabolic process acyl-CoA metabolic process ribonucleotide metabolic process nucleobase-containing small molecule metabolic process purine-containing compound biosynthetic process acyl-CoA biosynthetic process purine nucleoside bisphosphate biosynthetic process amide metabolic process carbohydrate derivative biosynthetic process organonitrogen compound metabolic process nucleoside bisphosphate biosynthetic process fatty acid derivative biosynthetic process long-chain fatty-acyl-CoA biosynthetic process nucleobase-containing compound biosynthetic process fatty acid derivative metabolic process purine-containing compound metabolic process organophosphate metabolic process cellular process lipid metabolic process oxoacid metabolic process organic acid biosynthetic process organic acid metabolic process carboxylic acid biosynthetic process fatty acid elongation, saturated fatty acid fatty acid metabolic process monocarboxylic acid biosynthetic process small molecule biosynthetic process carboxylic acid metabolic process fatty acid biosynthetic process fatty acid elongation cellular lipid metabolic process monocarboxylic acid metabolic process very long-chain fatty acid metabolic process very long-chain fatty acid biosynthetic process unsaturated fatty acid metabolic process unsaturated fatty acid biosynthetic process fatty acid elongation, polyunsaturated fatty acid fatty acid elongation, unsaturated fatty acid membrane lipid metabolic process sphingolipid biosynthetic process sphingolipid metabolic process membrane lipid biosynthetic process fatty acid elongation, monounsaturated fatty acid	membrane-bounded organelle intracellular organelle intracellular anatomical structure organelle endoplasmic reticulum cytoplasm cellular anatomical entity intracellular membrane-bounded organelle endomembrane system organelle subcompartment membrane endoplasmic reticulum subcompartment nuclear outer membrane-endoplasmic reticulum membrane network organelle membrane membrane-bounded organelle intracellular organelle intracellular anatomical structure organelle endoplasmic reticulum cytoplasm cellular anatomical entity intracellular membrane-bounded organelle endomembrane system organelle subcompartment membrane endoplasmic reticulum subcompartment nuclear outer membrane-endoplasmic reticulum membrane network organelle membrane endoplasmic reticulum membrane

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B	IPR033670	Elongation of very long chain fatty acids protein 7	Family
A, B	IPR002076	ELO family	Family
A, B	IPR030457	ELO family, conserved site	Conserved Site

Pharos: Disease Associations Pharos Homepage Annotation

Chains	Drug Target	Associated Disease
A, B	Pharos: A1L3X0	tuberculosis acute myeloid leukemia exocrine pancreatic carcinoma glioblastoma lung carcinoma medulloblastoma ovarian cancer psoriasis astrocytic tumor gastric cancer interstitial cystitis malignant glioma oligodendroglioma primitive neuroectodermal tumor spina bifida tuberculosis acute myeloid leukemia exocrine pancreatic carcinoma glioblastoma lung carcinoma medulloblastoma ovarian cancer psoriasis astrocytic tumor gastric cancer interstitial cystitis malignant glioma oligodendroglioma primitive neuroectodermal tumor spina bifida atypical teratoid rhabdoid tumor gastric carcinoma large cell medulloblastoma malignant pancreatic neoplasm osteosarcoma progressive supranuclear palsy

Membrane Protein Annotation: OPM OPM Database Homepage

Chains	External Link	Type	Class	Superfamily	Family
A, B	OPM	Transmembrane	Alpha-helical polytopic	ELO/TMPIT superfamily	ELO family

Membrane Protein Annotation: PDBTM PDBTM Database Homepage

Chains	External Link	Comment
A, B	PDBTM	Annotated as membrane protein by PDBTM

Membrane Protein Annotation: mpstruc mpstruc Database Homepage

Chains	Resource Link	Group	Subgroup	Protein
A, B	mpstruc	TRANSMEMBRANE PROTEINS: ALPHA-HELICAL	Very Long Chain Fatty Acid Elongases	ELOVL fatty acid elongase 7 (ELOVL7)

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.