6XJF

X-ray crystal structure of Pyrococcus furiosus general transcription factor TFE-alpha (SeMet labeled protein)

External Resource: Annotation

Domain Annotation: ECOD Classification
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	PF02002	e6xjfA1	A: alpha arrays	X: HTH	H: HTH	T: winged	F: PF02002	ECOD (1.6)
B	PF02002	e6xjfB1	A: alpha arrays	X: HTH	H: HTH	T: winged	F: PF02002	ECOD (1.6)
C	PF02002	e6xjfC1	A: alpha arrays	X: HTH	H: HTH	T: winged	F: PF02002	ECOD (1.6)
E	PF02002	e6xjfE1	A: alpha arrays	X: HTH	H: HTH	T: winged	F: PF02002	ECOD (1.6)
F	PF02002	e6xjfF1	A: alpha arrays	X: HTH	H: HTH	T: winged	F: PF02002	ECOD (1.6)
G	PF02002	e6xjfG1	A: alpha arrays	X: HTH	H: HTH	T: winged	F: PF02002	ECOD (1.6)
H	PF02002	e6xjfH1	A: alpha arrays	X: HTH	H: HTH	T: winged	F: PF02002	ECOD (1.6)
D	PF02002	e6xjfD1	A: alpha arrays	X: HTH	H: HTH	T: winged	F: PF02002	ECOD (1.6)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B, C, D, E A, B, C, D, E, F, G, H	PF02002	TFIIE alpha subunit (TFIIE_alpha)	TFIIE alpha subunit	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B, C, D, E A, B, C, D, E, F, G, H	Transcription factor E	DNA binding binding organic cyclic compound binding nucleic acid binding	regulation of cellular process cellular biosynthetic process RNA metabolic process regulation of primary metabolic process nucleobase-containing compound metabolic process RNA biosynthetic process nucleic acid biosynthetic process DNA-templated transcription regulation of RNA metabolic process organic substance metabolic process organic substance biosynthetic process regulation of nucleobase-containing compound metabolic process regulation of RNA biosynthetic process regulation of biosynthetic process regulation of cellular process cellular biosynthetic process RNA metabolic process regulation of primary metabolic process nucleobase-containing compound metabolic process RNA biosynthetic process nucleic acid biosynthetic process DNA-templated transcription regulation of RNA metabolic process organic substance metabolic process organic substance biosynthetic process regulation of nucleobase-containing compound metabolic process regulation of RNA biosynthetic process regulation of biosynthetic process regulation of biological process cellular metabolic process biological regulation primary metabolic process regulation of cellular metabolic process regulation of macromolecule metabolic process nucleobase-containing compound biosynthetic process gene expression macromolecule biosynthetic process nucleic acid metabolic process regulation of cellular biosynthetic process organic cyclic compound metabolic process regulation of gene expression biosynthetic process organic cyclic compound biosynthetic process metabolic process regulation of macromolecule biosynthetic process cellular process regulation of DNA-templated transcription macromolecule metabolic process regulation of metabolic process transcription by RNA polymerase II transcription initiation at RNA polymerase II promoter DNA-templated transcription initiation	-

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B, C, D, E A, B, C, D, E, F, G, H	IPR039997	Transcription factor E	Family
A, B, C, D, E A, B, C, D, E, F, G, H	IPR024550	TFIIEalpha/SarR/Rpc3 HTH domain	Domain
A, B, C, D, E A, B, C, D, E, F, G, H	IPR017919	Transcription factor TFE/TFIIEalpha HTH domain	Domain
A, B, C, D, E A, B, C, D, E, F, G, H	IPR016481	Transcription factor TFE, archaea	Family
A, B, C, D, E A, B, C, D, E, F, G, H	IPR002853	Transcription initiation factor IIE subunit alpha, N-terminal	Domain
A, B, C, D, E A, B, C, D, E, F, G, H	IPR036388	Winged helix-like DNA-binding domain superfamily	Homologous Superfamily
A, B, C, D, E A, B, C, D, E, F, G, H	IPR036390	Winged helix DNA-binding domain superfamily	Homologous Superfamily

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.