6W7S
Ketoreductase from module 1 of the 6-deoxyerythronolide B synthase (KR1) in complex with antibody fragment (Fab) 2G10
Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage
Domain Annotation: SCOP2 Classification SCOP2 Database Homepage
Chains | Type | Family Name | Domain Identifier | Family Identifier | Provenance Source (Version) |
---|---|---|---|---|---|
A | SCOP2B Superfamily | SDR-like | 8000377 | 3000038 | SCOP2B (2022-06-29) |
Domain Annotation: ECOD Classification ECOD Database Homepage
Chains | Family Name | Domain Identifier | Architecture | Possible Homology | Homology | Topology | Family | Provenance Source (Version) |
---|---|---|---|---|---|---|---|---|
A | F_UNCLASSIFIED | e6w7sA2 | A: a/b three-layered sandwiches | X: Rossmann-like | H: Rossmann-related | T: NAD(P)-binding Rossmann-fold domains | F: F_UNCLASSIFIED | ECOD (1.6) |
A | PF08659 | e6w7sA1 | A: a/b three-layered sandwiches | X: Rossmann-like | H: Rossmann-related | T: NAD(P)-binding Rossmann-fold domains | F: PF08659 | ECOD (1.6) |
B [auth H] | PF07654 | e6w7sH1 | A: beta sandwiches | X: Immunoglobulin-like beta-sandwich | H: Immunoglobulin-related | T: Immunoglobulin/Fibronectin type III/E set domains/PapD-like | F: PF07654 | ECOD (1.6) |
B [auth H] | PF07686 | e6w7sH2 | A: beta sandwiches | X: Immunoglobulin-like beta-sandwich | H: Immunoglobulin-related | T: Immunoglobulin/Fibronectin type III/E set domains/PapD-like | F: PF07686 | ECOD (1.6) |
C [auth L] | PF07654 | e6w7sL2 | A: beta sandwiches | X: Immunoglobulin-like beta-sandwich | H: Immunoglobulin-related | T: Immunoglobulin/Fibronectin type III/E set domains/PapD-like | F: PF07654 | ECOD (1.6) |
C [auth L] | PF07686 | e6w7sL1 | A: beta sandwiches | X: Immunoglobulin-like beta-sandwich | H: Immunoglobulin-related | T: Immunoglobulin/Fibronectin type III/E set domains/PapD-like | F: PF07686 | ECOD (1.6) |
SAbDab Antibody Annotation SAbDab Database Homepage
Chain | Chain Class | Chain Subclass | Chain Type | Antigen Name(s) | Provenance Source |
---|---|---|---|---|---|
B [auth H] | Heavy Chain | IGHV3 | - | eryai | SAbDab (2024-04-26) |
C [auth L] | Light Chain | IGLV5 | Lambda | eryai | SAbDab (2024-04-26) |
Protein Family Annotation Pfam Database Homepage
Chains | Accession | Name | Description | Comments | Source |
---|---|---|---|---|---|
PF08659 | KR domain (KR) | KR domain | - | Family | |
Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage
InterPro: Protein Family Classification InterPro Database Homepage
Chains | Accession | Name | Type |
---|---|---|---|
IPR016035 | Acyl transferase/acyl hydrolase/lysophospholipase | Homologous Superfamily | |
IPR014031 | Beta-ketoacyl synthase, C-terminal | Domain | |
IPR006162 | Phosphopantetheine attachment site | PTM | |
IPR032821 | Polyketide synthase, C-terminal extension | Domain | |
IPR009081 | Phosphopantetheine binding ACP domain | Domain | |
IPR014030 | Beta-ketoacyl synthase, N-terminal | Domain | |
IPR013968 | Polyketide synthase, ketoreductase domain | Domain | |
IPR016039 | Thiolase-like | Homologous Superfamily | |
IPR001227 | Acyl transferase domain superfamily | Homologous Superfamily | |
IPR016036 | Malonyl-CoA ACP transacylase, ACP-binding | Homologous Superfamily | |
IPR036291 | NAD(P)-binding domain superfamily | Homologous Superfamily | |
IPR020806 | Polyketide synthase, phosphopantetheine-binding domain | Domain | |
IPR014043 | Acyl transferase | Domain | |
IPR018201 | Beta-ketoacyl synthase, active site | Active Site | |
IPR020841 | Polyketide synthase, beta-ketoacyl synthase domain | Domain | |
IPR036736 | ACP-like superfamily | Homologous Superfamily |