6V88

Solution NMR structure of Dictyostelium discoideum Skp1A (truncated) dimer

External Resource: Annotation

Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2B Superfamily	POZ domain	8098736	3000894	SCOP2B (2022-06-29)
A	SCOP2B Superfamily	Skp1 dimerisation domain-like	8101064	3000564	SCOP2B (2022-06-29)
B	SCOP2 Family	Skp1 dimerisation domain-like	8101063	4001926	SCOP2 (2022-06-29)
B	SCOP2 Family	BTB/POZ domain	8098735	4001139	SCOP2 (2022-06-29)
B	SCOP2 Superfamily	Skp1 dimerisation domain-like	8101064	3000564	SCOP2 (2022-06-29)
B	SCOP2 Superfamily	POZ domain	8098736	3000894	SCOP2 (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	Skp1_POZ	e6v88A1	A: a+b two layers	X: POZ domain (From Topology)	H: POZ domain (From Topology)	T: POZ domain	F: Skp1_POZ	ECOD (1.6)
B	Skp1_POZ	e6v88B1	A: a+b two layers	X: POZ domain (From Topology)	H: POZ domain (From Topology)	T: POZ domain	F: Skp1_POZ	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	3.30.710.10	Alpha Beta	2-Layer Sandwich	Potassium Channel Kv1.1	Chain A	CATH (utative)
B	3.30.710.10	Alpha Beta	2-Layer Sandwich	Potassium Channel Kv1.1	Chain A	CATH (utative)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B	PF03931	Skp1 family, tetramerisation domain (Skp1_POZ)	Skp1 family, tetramerisation domain	-	Domain
A, B	PF01466	Skp1 family, dimerisation domain (Skp1)	Skp1 family, dimerisation domain	-	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B	SCF ubiquitin ligase complex protein SKP1a	protein binding binding cullin family protein binding WD40-repeat domain binding protein domain specific binding F-box domain binding identical protein binding	developmental process sorocarp development biological process involved in intraspecies interaction between organisms anatomical structure development socially cooperative development organonitrogen compound metabolic process primary metabolic process organic substance metabolic process protein ubiquitination macromolecule modification metabolic process protein metabolic process macromolecule metabolic process post-translational protein modification developmental process sorocarp development biological process involved in intraspecies interaction between organisms anatomical structure development socially cooperative development organonitrogen compound metabolic process primary metabolic process organic substance metabolic process protein ubiquitination macromolecule modification metabolic process protein metabolic process macromolecule metabolic process post-translational protein modification protein modification process protein modification by small protein conjugation protein modification by small protein conjugation or removal organonitrogen compound catabolic process catabolic process proteolysis involved in protein catabolic process proteasomal protein catabolic process protein catabolic process proteasome-mediated ubiquitin-dependent protein catabolic process macromolecule catabolic process modification-dependent macromolecule catabolic process modification-dependent protein catabolic process proteolysis SCF-dependent proteasomal ubiquitin-dependent protein catabolic process ubiquitin-dependent protein catabolic process organic substance catabolic process	cell periphery cell cortex intracellular anatomical structure cytoplasm cellular anatomical entity cytoplasmic ubiquitin ligase complex protein-containing complex ubiquitin ligase complex catalytic complex transferase complex cullin-RING ubiquitin ligase complex SCF ubiquitin ligase complex cytoplasmic SCF ubiquitin ligase complex intracellular protein-containing complex cell periphery cell cortex intracellular anatomical structure cytoplasm cellular anatomical entity cytoplasmic ubiquitin ligase complex protein-containing complex ubiquitin ligase complex catalytic complex transferase complex cullin-RING ubiquitin ligase complex SCF ubiquitin ligase complex cytoplasmic SCF ubiquitin ligase complex intracellular protein-containing complex membrane-bounded organelle intracellular organelle organelle nucleus intracellular membrane-bounded organelle

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B	IPR016073	SKP1 component, POZ domain	Domain
A, B	IPR036296	SKP1-like, dimerisation domain superfamily	Homologous Superfamily
A, B	IPR001232	S-phase kinase-associated protein 1-like	Family
A, B	IPR016072	SKP1 component, dimerisation	Domain
A, B	IPR011333	SKP1/BTB/POZ domain superfamily	Homologous Superfamily
A, B	IPR016897	S-phase kinase-associated protein 1	Family

RCSB PDB Core Operations are funded by the National Science Foundation (DBI-1832184), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.