Annotations: 6V55

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A	PF01825	GPCR proteolysis site, GPS, motif (GPS)	GPCR proteolysis site, GPS, motif	-	Motif
A	PF00354	Pentaxin family (Pentaxin)	Pentaxin family	Pentaxins are also known as pentraxins.	Domain
A	PF00431	CUB domain (CUB)	CUB domain	-	Domain
B [auth Q]	PF01825	GPCR proteolysis site, GPS, motif (GPS)	GPCR proteolysis site, GPS, motif	-	Motif

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A	Adhesion G-protein coupled receptor G6	extracellular matrix binding binding molecular transducer activity G protein-coupled receptor activity transmembrane signaling receptor activity signaling receptor activity collagen binding protein-containing complex binding protein binding laminin binding	developmental process heart development multicellular organism development multicellular organismal process anatomical structure development animal organ development circulatory system development system development ear development sensory organ development cellular developmental process peripheral nervous system axon ensheathment peripheral nervous system development cell development developmental process heart development multicellular organism development multicellular organismal process anatomical structure development animal organ development circulatory system development system development ear development sensory organ development cellular developmental process peripheral nervous system axon ensheathment peripheral nervous system development cell development nervous system development glial cell development myelination neurogenesis Schwann cell development gliogenesis axon ensheathment ensheathment of neurons glial cell differentiation cell differentiation myelination in peripheral nervous system cellular process Schwann cell differentiation posterior lateral line system development posterior lateral line nerve glial cell morphogenesis involved in differentiation posterior lateral line nerve glial cell differentiation lateral line nerve glial cell development myelination of lateral line nerve axons posterior lateral line nerve glial cell development cell morphogenesis nerve development mechanosensory lateral line system development lateral line nerve glial cell morphogenesis involved in differentiation sensory system development posterior lateral line nerve development lateral line system development anatomical structure morphogenesis lateral line nerve glial cell differentiation cranial nerve development lateral line nerve development myelination of posterior lateral line nerve axons cellular component assembly involved in morphogenesis myelin assembly cellular component organization cellular component biogenesis cellular anatomical entity morphogenesis cellular component assembly cellular component organization or biogenesis peripheral nervous system myelin formation anatomical structure formation involved in morphogenesis regulation of sprouting angiogenesis regulation of developmental process angiogenesis regulation of vasculature development tube morphogenesis regulation of multicellular organismal process regulation of anatomical structure morphogenesis blood vessel development regulation of multicellular organismal development regulation of biological process blood vessel morphogenesis tube development biological regulation sprouting angiogenesis vasculature development regulation of angiogenesis cardiac chamber morphogenesis heart trabecula formation heart morphogenesis cardiac chamber development animal organ morphogenesis heart trabecula morphogenesis trabecula formation trabecula morphogenesis cellular response to stimulus regulation of cellular process response to stimulus signaling adenylate cyclase-activating G protein-coupled receptor signaling pathway cell communication adenylate cyclase-modulating G protein-coupled receptor signaling pathway G protein-coupled receptor signaling pathway signal transduction cell surface receptor signaling pathway ossification intracellular signal transduction cAMP-mediated signaling intracellular signaling cassette organelle organization mitochondrion organization tube formation embryo development inner ear development semicircular canal formation embryonic organ development ear morphogenesis embryonic organ morphogenesis semicircular canal morphogenesis embryonic morphogenesis semicircular canal development sensory organ morphogenesis inner ear morphogenesis semicircular canal fusion tube closure	cell periphery plasma membrane membrane cellular anatomical entity
B [auth Q]	Adhesion G-protein coupled receptor G6	extracellular matrix binding binding molecular transducer activity G protein-coupled receptor activity transmembrane signaling receptor activity signaling receptor activity collagen binding protein-containing complex binding protein binding laminin binding	developmental process heart development multicellular organism development multicellular organismal process anatomical structure development animal organ development circulatory system development system development ear development sensory organ development cellular developmental process peripheral nervous system axon ensheathment peripheral nervous system development cell development developmental process heart development multicellular organism development multicellular organismal process anatomical structure development animal organ development circulatory system development system development ear development sensory organ development cellular developmental process peripheral nervous system axon ensheathment peripheral nervous system development cell development nervous system development glial cell development myelination neurogenesis Schwann cell development gliogenesis axon ensheathment ensheathment of neurons glial cell differentiation cell differentiation myelination in peripheral nervous system cellular process Schwann cell differentiation posterior lateral line system development posterior lateral line nerve glial cell morphogenesis involved in differentiation posterior lateral line nerve glial cell differentiation lateral line nerve glial cell development myelination of lateral line nerve axons posterior lateral line nerve glial cell development cell morphogenesis nerve development mechanosensory lateral line system development lateral line nerve glial cell morphogenesis involved in differentiation sensory system development posterior lateral line nerve development lateral line system development anatomical structure morphogenesis lateral line nerve glial cell differentiation cranial nerve development lateral line nerve development myelination of posterior lateral line nerve axons cellular component assembly involved in morphogenesis myelin assembly cellular component organization cellular component biogenesis cellular anatomical entity morphogenesis cellular component assembly cellular component organization or biogenesis peripheral nervous system myelin formation anatomical structure formation involved in morphogenesis regulation of sprouting angiogenesis regulation of developmental process angiogenesis regulation of vasculature development tube morphogenesis regulation of multicellular organismal process regulation of anatomical structure morphogenesis blood vessel development regulation of multicellular organismal development regulation of biological process blood vessel morphogenesis tube development biological regulation sprouting angiogenesis vasculature development regulation of angiogenesis cardiac chamber morphogenesis heart trabecula formation heart morphogenesis cardiac chamber development animal organ morphogenesis heart trabecula morphogenesis trabecula formation trabecula morphogenesis cellular response to stimulus regulation of cellular process response to stimulus signaling adenylate cyclase-activating G protein-coupled receptor signaling pathway cell communication adenylate cyclase-modulating G protein-coupled receptor signaling pathway G protein-coupled receptor signaling pathway signal transduction cell surface receptor signaling pathway ossification intracellular signal transduction cAMP-mediated signaling intracellular signaling cassette organelle organization mitochondrion organization tube formation embryo development inner ear development semicircular canal formation embryonic organ development ear morphogenesis embryonic organ morphogenesis semicircular canal morphogenesis embryonic morphogenesis semicircular canal development sensory organ morphogenesis inner ear morphogenesis semicircular canal fusion tube closure	cell periphery plasma membrane membrane cellular anatomical entity

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A	IPR017983	GPCR, family 2, secretin-like, conserved site	Conserved Site
A	IPR001759	Pentraxin-related	Family
A	IPR035914	Spermadhesin, CUB domain superfamily	Homologous Superfamily
A	IPR013320	Concanavalin A-like lectin/glucanase domain superfamily	Homologous Superfamily
A	IPR000832	GPCR, family 2, secretin-like	Family
A	IPR000203	GPS motif	Conserved Site
A	IPR000859	CUB domain	Domain
A	IPR017981	GPCR, family 2-like, 7TM	Domain
A	IPR046338	GAIN domain superfamily	Homologous Superfamily
B [auth Q]	IPR017983	GPCR, family 2, secretin-like, conserved site	Conserved Site
B [auth Q]	IPR001759	Pentraxin-related	Family
B [auth Q]	IPR035914	Spermadhesin, CUB domain superfamily	Homologous Superfamily
B [auth Q]	IPR013320	Concanavalin A-like lectin/glucanase domain superfamily	Homologous Superfamily
B [auth Q]	IPR000832	GPCR, family 2, secretin-like	Family
B [auth Q]	IPR000203	GPS motif	Conserved Site
B [auth Q]	IPR000859	CUB domain	Domain
B [auth Q]	IPR017981	GPCR, family 2-like, 7TM	Domain
B [auth Q]	IPR046338	GAIN domain superfamily	Homologous Superfamily

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.