Annotations: 6V1S

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
H [auth Z]	PF03496	e6v1sZ1	A: a+b complex topology	X: ADP-ribosylation (From Topology)	H: ADP-ribosylation (From Topology)	T: ADP-ribosylation	F: PF03496	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
H [auth Z]	3.90.176.10	Alpha Beta	Alpha-Beta Complex	Toxin ADP-ribosyltransferase	Chain A, domain 1	CATH (utative)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B, C, D, E A, B, C, D, E, F, G	PF17475	Clostridial binary toxin B/anthrax toxin PA domain 2 (Binary_toxB_2)	Clostridial binary toxin B/anthrax toxin PA domain 2	This domain forms the middle beta sandwish domain in anthrax toxin.	Domain
A, B, C, D, E A, B, C, D, E, F, G	PF03495	Clostridial binary toxin B/anthrax toxin PA Ca-binding domain (Binary_toxB)	Clostridial binary toxin B/anthrax toxin PA Ca-binding domain	This domain is a calcium binding domain in the anthrax toxin protective antigen.	Domain
A, B, C, D, E A, B, C, D, E, F, G	PF17476	Clostridial binary toxin B/anthrax toxin PA domain 3 (Binary_toxB_3)	Clostridial binary toxin B/anthrax toxin PA domain 3	This entry represents the beta-grasp domain in anthrax protective antigen.	Domain
H [auth Z]	PF03496	ADP-ribosyltransferase exoenzyme (ADPrib_exo_Tox)	ADP-ribosyltransferase exoenzyme	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B, C, D, E A, B, C, D, E, F, G	ADP-ribosyltransferase binding component	transferase activity catalytic activity identical protein binding protein binding binding	cellular component organization cellular component biogenesis cellular component assembly protein-containing complex organization protein complex oligomerization protein-containing complex assembly protein homooligomerization cellular process cellular component organization or biogenesis	extracellular region cellular anatomical entity
H [auth Z]	ADP-ribosylating binary toxin enzymatic subunit CdtA	binding nucleoside phosphate binding organic cyclic compound binding nucleotide binding heterocyclic compound binding small molecule binding transferase activity catalytic activity	-	extracellular region cellular anatomical entity

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B, C, D, E A, B, C, D, E, F, G	IPR035331	Clostridial binary toxin B/anthrax toxin PA, domain 3	Domain
A, B, C, D, E A, B, C, D, E, F, G	IPR011658	PA14 domain	Domain
A, B, C, D, E A, B, C, D, E, F, G	IPR027439	Protective antigen, heptamerisation domain	Domain
A, B, C, D, E A, B, C, D, E, F, G	IPR035088	Protective antigen, Ca-binding domain	Domain
A, B, C, D, E A, B, C, D, E, F, G	IPR037149	Protective antigen, heptamerisation domain superfamily	Homologous Superfamily
A, B, C, D, E A, B, C, D, E, F, G	IPR003896	Bacterial exotoxin B	Family
H [auth Z]	IPR003540	ADP ribosyltransferase	Domain
H [auth Z]	IPR016013	Binary exotoxin A, clostridial type	Family

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.