Annotations: 6TZN

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	PF19977	e6tznA1	A: a+b two layers	X: Alpha-beta plaits	H: RNA-binding domain, RBD (From Topology)	T: RNA-binding domain, RBD	F: PF19977	ECOD (1.6)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A	PF19977	xRRM domain (xRRM)	xRRM domain	This entry represents the xRRM domain, which is an atypical RRM domain [1].	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A	Protein pof8	RNA binding binding telomerase RNA binding organic cyclic compound binding nucleic acid binding protein-containing complex binding chromatin binding	regulation of cellular process negative regulation of biological process regulation of primary metabolic process nucleobase-containing compound metabolic process post-transcriptional regulation of gene expression regulation of RNA metabolic process organic substance biosynthetic process telomerase RNA stabilization negative regulation of nucleobase-containing compound metabolic process regulation of nucleobase-containing compound metabolic process regulation of biological quality RNA catabolic process regulation of biological process negative regulation of metabolic process regulation of cellular process negative regulation of biological process regulation of primary metabolic process nucleobase-containing compound metabolic process post-transcriptional regulation of gene expression regulation of RNA metabolic process organic substance biosynthetic process telomerase RNA stabilization negative regulation of nucleobase-containing compound metabolic process regulation of nucleobase-containing compound metabolic process regulation of biological quality RNA catabolic process regulation of biological process negative regulation of metabolic process cellular metabolic process primary metabolic process regulation of cellular metabolic process nucleobase-containing compound catabolic process organic cyclic compound metabolic process regulation of gene expression biosynthetic process nucleic acid catabolic process metabolic process regulation of macromolecule biosynthetic process macromolecule metabolic process regulation of metabolic process negative regulation of RNA metabolic process catabolic process cellular biosynthetic process RNA metabolic process macromolecule catabolic process organic substance metabolic process negative regulation of macromolecule metabolic process negative regulation of catabolic process regulation of biosynthetic process biological regulation negative regulation of RNA catabolic process regulation of macromolecule metabolic process regulation of catabolic process gene expression macromolecule biosynthetic process nucleic acid metabolic process organic cyclic compound catabolic process regulation of cellular biosynthetic process RNA stabilization regulation of RNA stability cellular process organic substance catabolic process telomere organization RNA-templated DNA biosynthetic process telomere maintenance via telomere lengthening cellular component organization nucleic acid biosynthetic process cellular component organization or biogenesis telomere maintenance via telomerase chromosome organization DNA metabolic process nucleobase-containing compound biosynthetic process telomere maintenance organelle organization organic cyclic compound biosynthetic process DNA biosynthetic process snRNA metabolic process snRNA processing RNA processing nuclear RNA surveillance RNA surveillance ribonucleoprotein complex biogenesis telomerase holoenzyme complex assembly protein-containing complex organization telomerase catalytic core complex assembly protein-RNA complex assembly cellular component biogenesis protein-RNA complex organization cellular component assembly protein-containing complex assembly	membrane-bounded organelle protein-containing complex intracellular anatomical structure catalytic complex nucleus nuclear protein-containing complex intracellular membrane-bounded organelle cellular anatomical entity intracellular organelle telomerase holoenzyme complex organelle ribonucleoprotein complex cytoplasm cytosol membrane-bounded organelle protein-containing complex intracellular anatomical structure catalytic complex nucleus nuclear protein-containing complex intracellular membrane-bounded organelle cellular anatomical entity intracellular organelle telomerase holoenzyme complex organelle ribonucleoprotein complex cytoplasm cytosol sno(s)RNA-containing ribonucleoprotein complex intracellular non-membrane-bounded organelle chromosome, telomeric repeat region chromosome chromosome, telomeric region chromosomal region non-membrane-bounded organelle

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A	IPR014886	La protein, xRRM domain	Domain
A	IPR012677	Nucleotide-binding alpha-beta plait domain superfamily	Homologous Superfamily
A	IPR045537	La-related protein 7 homolog, xRRM domain	Domain

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.