6TU2

Crystal structure of rat annexin A11

External Resource: Annotation

Domain Annotation: SCOP/SCOPe Classification
Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A	d6tu2a_	All alpha proteins	Annexin	Annexin	automated matches	automated matches	Norway rat (Rattus norvegicus ) [TaxId: 10116 ],	SCOPe (2.08)
B	d6tu2b_	All alpha proteins	Annexin	Annexin	automated matches	automated matches	Norway rat (Rattus norvegicus ) [TaxId: 10116 ],	SCOPe (2.08)
C	d6tu2c_	All alpha proteins	Annexin	Annexin	automated matches	automated matches	Norway rat (Rattus norvegicus ) [TaxId: 10116 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2B Superfamily	Annexin	8094999	3000627	SCOP2B (2022-06-29)
B	SCOP2B Superfamily	Annexin	8094999	3000627	SCOP2B (2022-06-29)
C	SCOP2 Family	Annexin	8094998	4001063	SCOP2 (2022-06-29)
C	SCOP2 Superfamily	Annexin	8094999	3000627	SCOP2 (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	PF00191	e6tu2A3	A: alpha arrays	X: Annexin (From Topology)	H: Annexin (From Topology)	T: Annexin	F: PF00191	ECOD (1.6)
B	PF00191	e6tu2B3	A: alpha arrays	X: Annexin (From Topology)	H: Annexin (From Topology)	T: Annexin	F: PF00191	ECOD (1.6)
C	PF00191	e6tu2C2	A: alpha arrays	X: Annexin (From Topology)	H: Annexin (From Topology)	T: Annexin	F: PF00191	ECOD (1.6)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B, C	PF00191	Annexin (Annexin)	Annexin	This family of annexins also includes giardin that has been shown to function as an annexin [1].	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B, C	Annexin	cation binding ion binding binding calcium ion binding metal ion binding small molecule binding calcium-dependent phospholipid binding phospholipid binding lipid binding phosphatidylethanolamine binding protein binding S100 protein binding calcium-dependent protein binding	response to stimulus response to metal ion response to chemical response to calcium ion response to inorganic substance localization import into cell transport phagocytosis cellular process endocytosis establishment of localization vesicle-mediated transport cytokinetic process response to stimulus response to metal ion response to chemical response to calcium ion response to inorganic substance localization import into cell transport phagocytosis cellular process endocytosis establishment of localization vesicle-mediated transport cytokinetic process cell cycle cytokinesis cell division cell cycle process	midbody cellular anatomical entity membrane-bounded organelle intracellular organelle organelle envelope intracellular anatomical structure organelle nuclear envelope nucleus intracellular membrane-bounded organelle endomembrane system lytic vacuole intracellular vesicle azurophil granule midbody cellular anatomical entity membrane-bounded organelle intracellular organelle organelle envelope intracellular anatomical structure organelle nuclear envelope nucleus intracellular membrane-bounded organelle endomembrane system lytic vacuole intracellular vesicle azurophil granule vacuole cytoplasmic vesicle secretory granule primary lysosome secretory vesicle cytoplasm vesicle lysosome phagocytic vesicle endocytic vesicle cytoskeleton spindle intracellular non-membrane-bounded organelle microtubule cytoskeleton non-membrane-bounded organelle specific granule membrane-enclosed lumen intracellular organelle lumen nucleoplasm organelle lumen nuclear lumen

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B, C	IPR001464	Annexin	Family
A, B, C	IPR018252	Annexin repeat, conserved site	Conserved Site
A, B, C	IPR008157	Annexin A11	Family
A, B, C	IPR018502	Annexin repeat	Repeat
A, B, C	IPR037104	Annexin superfamily	Homologous Superfamily

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.