6T7O

X-ray structure of the C-terminal domain of S. aureus Hibernating Promoting Factor (CTD-SaHPF)

External Resource: Annotation

Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
B	SCOP2B Superfamily	Hibernation promoting factor (HPF) C-terminal domain-like	8086264	3002136	SCOP2B (2022-06-29)
A	SCOP2B Superfamily	Hibernation promoting factor (HPF) C-terminal domain-like	8086264	3002136	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
B	PF16321	e6t7oB1	A: a+b two layers	X: Ribosome-associated factor Y (From Topology)	H: Ribosome-associated factor Y (From Topology)	T: Ribosome-associated factor Y	F: PF16321	ECOD (1.6)
A	PF16321	e6t7oA1	A: a+b two layers	X: Ribosome-associated factor Y (From Topology)	H: Ribosome-associated factor Y (From Topology)	T: Ribosome-associated factor Y	F: PF16321	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
B	3.30.505.50	Alpha Beta	2-Layer Sandwich	SHC Adaptor Protein	Sigma 54 modulation/S30EA ribosomal protein, C-terminal domain	CATH (utative)
A	3.30.505.50	Alpha Beta	2-Layer Sandwich	SHC Adaptor Protein	Sigma 54 modulation/S30EA ribosomal protein, C-terminal domain	CATH (utative)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B	PF16321	Sigma 54 modulation/S30EA ribosomal protein C terminus (Ribosom_S30AE_C)	Sigma 54 modulation/S30EA ribosomal protein C terminus	This domain often occurs at the C-terminus of proteins containing Pfam:PF02482.	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B	Ribosome hibernation promotion factor	ribonucleoprotein complex binding protein-containing complex binding binding ribosomal small subunit binding ribosome binding	primary metabolic process metabolic process regulation of cellular process cellular biosynthetic process organonitrogen compound biosynthetic process negative regulation of biological process negative regulation of cellular metabolic process regulation of primary metabolic process post-transcriptional regulation of gene expression regulation of translational elongation negative regulation of translation organic substance metabolic process organic substance biosynthetic process negative regulation of cellular process primary metabolic process metabolic process regulation of cellular process cellular biosynthetic process organonitrogen compound biosynthetic process negative regulation of biological process negative regulation of cellular metabolic process regulation of primary metabolic process post-transcriptional regulation of gene expression regulation of translational elongation negative regulation of translation organic substance metabolic process organic substance biosynthetic process negative regulation of cellular process protein metabolic process negative regulation of protein metabolic process negative regulation of macromolecule metabolic process regulation of biosynthetic process regulation of biological process organonitrogen compound metabolic process cellular metabolic process regulation of protein metabolic process negative regulation of metabolic process biological regulation regulation of cellular metabolic process regulation of macromolecule metabolic process gene expression translation macromolecule biosynthetic process negative regulation of translational elongation negative regulation of cellular biosynthetic process regulation of cellular biosynthetic process regulation of gene expression negative regulation of gene expression biosynthetic process negative regulation of biosynthetic process regulation of translation negative regulation of macromolecule biosynthetic process translational elongation regulation of macromolecule biosynthetic process cellular process macromolecule metabolic process regulation of metabolic process	cytosolic small ribosomal subunit protein-containing complex intracellular anatomical structure small ribosomal subunit cellular anatomical entity intracellular organelle ribosomal subunit cytosolic ribosome organelle ribonucleoprotein complex intracellular non-membrane-bounded organelle ribosome cytoplasm cytosol cytosolic small ribosomal subunit protein-containing complex intracellular anatomical structure small ribosomal subunit cellular anatomical entity intracellular organelle ribosomal subunit cytosolic ribosome organelle ribonucleoprotein complex intracellular non-membrane-bounded organelle ribosome cytoplasm cytosol non-membrane-bounded organelle

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B	IPR003489	Ribosome hibernation promoting factor/RaiA	Family
A, B	IPR034694	Ribosome hibernation promoting factor, long/plastid	Family
A, B	IPR036567	Ribosome hibernation promotion factor-like	Homologous Superfamily
A, B	IPR032528	Sigma 54 modulation/S30EA ribosomal protein, C-terminal	Domain
A, B	IPR038416	Sigma 54 modulation/S30EA ribosomal protein, C-terminal domain superfamily	Homologous Superfamily

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.