6SXI

Antibody-anti-idiotype complex: AP33 Fab (hepatitis C virus E2 antibody) - B2.1A scFv (anti-idiotype)

External Resource: Annotation


Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

ChainsDomain InfoClassFoldSuperfamilyFamilyDomainSpeciesProvenance Source (Version)
A [auth H]d6sxih_ All beta proteins Immunoglobulin-like beta-sandwich Immunoglobulin V set domains (antibody variable domain-like) automated matches (Mus musculus ) [TaxId: 10090 ], SCOPe (2.08)
B [auth L]d6sxil2 All beta proteins Immunoglobulin-like beta-sandwich Immunoglobulin C1 set domains (antibody constant domain-like) automated matches (Mus musculus ) [TaxId: 10090 ], SCOPe (2.08)
B [auth L]d6sxil1 All beta proteins Immunoglobulin-like beta-sandwich Immunoglobulin automated matches automated matches (Mus musculus ) [TaxId: 10090 ], SCOPe (2.08)
C [auth A]d6sxia1 All beta proteins Immunoglobulin-like beta-sandwich Immunoglobulin V set domains (antibody variable domain-like) automated matches (Mus musculus ) [TaxId: 10090 ], SCOPe (2.08)
C [auth A]d6sxia2 Artifacts Tags Tags Tags N-terminal Tags (Mus musculus ) [TaxId: 10090 ], SCOPe (2.08)
D [auth B]d6sxib_ All beta proteins Immunoglobulin-like beta-sandwich Immunoglobulin automated matches automated matches (Mus musculus ) [TaxId: 10090 ], SCOPe (2.08)

Domain Annotation: ECOD Classification ECOD Database Homepage

ChainsFamily NameDomain Identifier ArchitecturePossible HomologyHomologyTopologyFamilyProvenance Source (Version)
A [auth H]PF07654e6sxiH2 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: PF07654ECOD (1.6)
A [auth H]PF07686e6sxiH1 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: PF07686ECOD (1.6)
B [auth L]PF07654e6sxiL1 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: PF07654ECOD (1.6)
B [auth L]PF07686e6sxiL2 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: PF07686ECOD (1.6)
C [auth A]PF07686e6sxiA1 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: PF07686ECOD (1.6)
D [auth B]PF07686e6sxiB1 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: PF07686ECOD (1.6)

IMGT Antibody Annotation IMGT Database Homepage

ChainProtein NameDescriptionOrganism NameGene Allele Name(s)Domain Name(s)Receptor TypeReceptor DescriptionProvenance Source
A [auth H]Fab AP33 VH-CH1 Mus musculus (house mouse) IGHV3-8*02, IGHJ4*01, IGHG1*02 V-DOMAIN VH, C-DOMAIN CH1 IG FAB-GAMMA-1_KAPPA IMGT (202416-0)
B [auth L]Fab AP33 L-KAPPA Mus musculus (house mouse) IGKV3-10*01, IGKJ1*01, IGKC*01, IGKC*02 V-DOMAIN V-KAPPA, C-DOMAIN C-KAPPA IG FAB-GAMMA-1_KAPPA IMGT (202416-0)
C [auth A]scFv B2.1A, anti-idiotope of AP33 VH Mus musculus (house mouse) IGHV1-53*01, IGHJ3*01 V-DOMAIN VH IG FV-HEAVY_KAPPA IMGT (202416-0)
D [auth B]scFv B2.1A, anti-idiotope of AP33 V-KAPPA Mus musculus (house mouse) IGKV6-14*01, IGKJ2*01 V-DOMAIN V-KAPPA IG FV-HEAVY_KAPPA IMGT (202416-0)

SAbDab Antibody Annotation SAbDab Database Homepage

ChainChain ClassChain SubclassChain TypeAntigen Name(s) Provenance Source
A [auth H]Heavy ChainIGHV3 --SAbDab (2024-04-26)
B [auth L]Light ChainIGKV3 Kappa-SAbDab (2024-04-26)
C [auth A]Heavy ChainIGHV1 --SAbDab (2024-04-26)
D [auth B]Light ChainIGKV6 Kappa-SAbDab (2024-04-26)