6SKQ
OXA-655_MEM. Structural insights into the enhanced carbapenemase efficiency of OXA-655 compared to OXA-10.
External Resource: Annotation
- Domain Annotation: SCOP/SCOPe Classification
- Domain Annotation: SCOP2 Classification
- Domain Annotation: ECOD Classification
- Domain Annotation: CATH
- AMR Gene: CARD Annotation
- AMR Gene Family: CARD Annotation
- Protein Family Annotation
- Gene Ontology: Gene Product Annotation
- InterPro: Protein Family Classification
Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage
Chains | Domain Info | Class | Fold | Superfamily | Family | Domain | Species | Provenance Source (Version) |
---|---|---|---|---|---|---|---|---|
A | d6skqa_ | Multi-domain proteins (alpha and beta) | beta-lactamase/transpeptidase-like | beta-lactamase/transpeptidase-like | beta-Lactamase/D-ala carboxypeptidase | automated matches | (Escherichia coli ) [TaxId: 562 ], | SCOPe (2.08) |
B | d6skqb_ | Multi-domain proteins (alpha and beta) | beta-lactamase/transpeptidase-like | beta-lactamase/transpeptidase-like | beta-Lactamase/D-ala carboxypeptidase | automated matches | (Escherichia coli ) [TaxId: 562 ], | SCOPe (2.08) |
C | d6skqc_ | Multi-domain proteins (alpha and beta) | beta-lactamase/transpeptidase-like | beta-lactamase/transpeptidase-like | beta-Lactamase/D-ala carboxypeptidase | automated matches | (Escherichia coli ) [TaxId: 562 ], | SCOPe (2.08) |
D | d6skqd_ | Multi-domain proteins (alpha and beta) | beta-lactamase/transpeptidase-like | beta-lactamase/transpeptidase-like | beta-Lactamase/D-ala carboxypeptidase | automated matches | (Escherichia coli ) [TaxId: 562 ], | SCOPe (2.08) |
Domain Annotation: SCOP2 Classification SCOP2 Database Homepage
Chains | Type | Family Name | Domain Identifier | Family Identifier | Provenance Source (Version) |
---|---|---|---|---|---|
A | SCOP2 Family | beta-Lactamase/D-ala carboxypeptidase | 8093705 | 4002685 | SCOP2 (2022-06-29) |
A | SCOP2 Superfamily | beta-lactamase/transpeptidase-like | 8093706 | 3001604 | SCOP2 (2022-06-29) |
B | SCOP2B Superfamily | beta-lactamase/transpeptidase-like | 8093706 | 3001604 | SCOP2B (2022-06-29) |
C | SCOP2B Superfamily | beta-lactamase/transpeptidase-like | 8093706 | 3001604 | SCOP2B (2022-06-29) |
D | SCOP2B Superfamily | beta-lactamase/transpeptidase-like | 8093706 | 3001604 | SCOP2B (2022-06-29) |
Domain Annotation: ECOD Classification ECOD Database Homepage
Chains | Family Name | Domain Identifier | Architecture | Possible Homology | Homology | Topology | Family | Provenance Source (Version) |
---|---|---|---|---|---|---|---|---|
A | PF00905 | e6skqA1 | A: alpha complex topology | X: alpha-helical domain in beta-lactamase/transpeptidase-like proteins (From Topology) | H: alpha-helical domain in beta-lactamase/transpeptidase-like proteins (From Topology) | T: alpha-helical domain in beta-lactamase/transpeptidase-like proteins | F: PF00905 | ECOD (1.6) |
A | PF00905 | e6skqA2 | A: a+b three layers | X: Profilin-like | H: a+b domain in beta-lactamase/transpeptidase-like proteins (From Topology) | T: a+b domain in beta-lactamase/transpeptidase-like proteins | F: PF00905 | ECOD (1.6) |
B | PF00905 | e6skqB1 | A: alpha complex topology | X: alpha-helical domain in beta-lactamase/transpeptidase-like proteins (From Topology) | H: alpha-helical domain in beta-lactamase/transpeptidase-like proteins (From Topology) | T: alpha-helical domain in beta-lactamase/transpeptidase-like proteins | F: PF00905 | ECOD (1.6) |
B | PF00905 | e6skqB2 | A: a+b three layers | X: Profilin-like | H: a+b domain in beta-lactamase/transpeptidase-like proteins (From Topology) | T: a+b domain in beta-lactamase/transpeptidase-like proteins | F: PF00905 | ECOD (1.6) |
C | PF00905 | e6skqC1 | A: alpha complex topology | X: alpha-helical domain in beta-lactamase/transpeptidase-like proteins (From Topology) | H: alpha-helical domain in beta-lactamase/transpeptidase-like proteins (From Topology) | T: alpha-helical domain in beta-lactamase/transpeptidase-like proteins | F: PF00905 | ECOD (1.6) |
C | PF00905 | e6skqC2 | A: a+b three layers | X: Profilin-like | H: a+b domain in beta-lactamase/transpeptidase-like proteins (From Topology) | T: a+b domain in beta-lactamase/transpeptidase-like proteins | F: PF00905 | ECOD (1.6) |
D | PF00905 | e6skqD2 | A: alpha complex topology | X: alpha-helical domain in beta-lactamase/transpeptidase-like proteins (From Topology) | H: alpha-helical domain in beta-lactamase/transpeptidase-like proteins (From Topology) | T: alpha-helical domain in beta-lactamase/transpeptidase-like proteins | F: PF00905 | ECOD (1.6) |
D | PF00905 | e6skqD1 | A: a+b three layers | X: Profilin-like | H: a+b domain in beta-lactamase/transpeptidase-like proteins (From Topology) | T: a+b domain in beta-lactamase/transpeptidase-like proteins | F: PF00905 | ECOD (1.6) |
Domain Annotation: CATH CATH Database Homepage
Chain | Domain | Class | Architecture | Topology | Homology | Provenance Source (Version) |
---|---|---|---|---|---|---|
A | 3.40.710.10 | Alpha Beta | 3-Layer(aba) Sandwich | Beta-lactamase | DD-peptidase/beta-lactamase superfamily | CATH (utative) |
B | 3.40.710.10 | Alpha Beta | 3-Layer(aba) Sandwich | Beta-lactamase | DD-peptidase/beta-lactamase superfamily | CATH (utative) |
C | 3.40.710.10 | Alpha Beta | 3-Layer(aba) Sandwich | Beta-lactamase | DD-peptidase/beta-lactamase superfamily | CATH (utative) |
D | 3.40.710.10 | Alpha Beta | 3-Layer(aba) Sandwich | Beta-lactamase | DD-peptidase/beta-lactamase superfamily | CATH (utative) |
AMR Gene: CARD Annotation CARD Database Homepage
Chains | Accession | Short Name | Description | Provenance Source (Version) |
---|---|---|---|---|
ARO:3005870 | OXA-655 | OXA-655 is a OXA beta-lactamase. | CARD (3.2.9) |
AMR Gene Family: CARD Annotation CARD Database Homepage
Chains | Accession | Gene Family | Drug Class | Resistance Machanism | Provenance Source (Version) |
---|---|---|---|---|---|
ARO:3007697 | OXA-10-like beta-lactamase | cephalosporin, penam | antibiotic inactivation | CARD (3.2.9) |