6SDG

Crystal structure of the DNA binding domain of M. polymorpha Auxin Response Factor 2 (MpARF2) in complex with High Affinity DNA

External Resource: Annotation

Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	PF02362	e6sdgA3	A: beta barrels	X: cradle loop barrel	H: RIFT-related	T: Type II restriction endonuclease effector domain	F: PF02362	ECOD (1.6)
A	F_UNCLASSIFIED	e6sdgA2	A: beta barrels	X: SH3	H: Auxin response factor dimerization domain and ancillary domain (From Topology)	T: Auxin response factor dimerization domain and ancillary domain	F: F_UNCLASSIFIED	ECOD (1.6)
A	PF06507	e6sdgA1	A: beta barrels	X: SH3	H: Auxin response factor dimerization domain and ancillary domain (From Topology)	T: Auxin response factor dimerization domain and ancillary domain	F: PF06507	ECOD (1.6)
B	PF02362	e6sdgB3	A: beta barrels	X: cradle loop barrel	H: RIFT-related	T: Type II restriction endonuclease effector domain	F: PF02362	ECOD (1.6)
B	F_UNCLASSIFIED	e6sdgB1	A: beta barrels	X: SH3	H: Auxin response factor dimerization domain and ancillary domain (From Topology)	T: Auxin response factor dimerization domain and ancillary domain	F: F_UNCLASSIFIED	ECOD (1.6)
B	PF06507	e6sdgB2	A: beta barrels	X: SH3	H: Auxin response factor dimerization domain and ancillary domain (From Topology)	T: Auxin response factor dimerization domain and ancillary domain	F: PF06507	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	2.40.330.10	Mainly Beta	Beta Barrel	At1g16640 B3 domain	DNA-binding pseudobarrel domain	CATH (utative)
A	2.30.30.1040	Mainly Beta	Roll	SH3 type barrels.		CATH (utative)
B	2.40.330.10	Mainly Beta	Beta Barrel	At1g16640 B3 domain	DNA-binding pseudobarrel domain	CATH (utative)
B	2.30.30.1040	Mainly Beta	Roll	SH3 type barrels.		CATH (utative)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B	PF06507	Auxin response factor (Auxin_resp)	Auxin response factor	-	Family
A, B	PF02362	B3 DNA binding domain (B3)	B3 DNA binding domain	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B	Auxin response factor	DNA binding binding organic cyclic compound binding nucleic acid binding	regulation of cellular process cellular biosynthetic process RNA metabolic process regulation of primary metabolic process nucleobase-containing compound metabolic process RNA biosynthetic process nucleic acid biosynthetic process DNA-templated transcription regulation of RNA metabolic process organic substance metabolic process organic substance biosynthetic process regulation of nucleobase-containing compound metabolic process regulation of RNA biosynthetic process regulation of biosynthetic process regulation of cellular process cellular biosynthetic process RNA metabolic process regulation of primary metabolic process nucleobase-containing compound metabolic process RNA biosynthetic process nucleic acid biosynthetic process DNA-templated transcription regulation of RNA metabolic process organic substance metabolic process organic substance biosynthetic process regulation of nucleobase-containing compound metabolic process regulation of RNA biosynthetic process regulation of biosynthetic process regulation of biological process cellular metabolic process biological regulation primary metabolic process regulation of cellular metabolic process regulation of macromolecule metabolic process nucleobase-containing compound biosynthetic process gene expression macromolecule biosynthetic process nucleic acid metabolic process regulation of cellular biosynthetic process organic cyclic compound metabolic process regulation of gene expression biosynthetic process organic cyclic compound biosynthetic process metabolic process regulation of macromolecule biosynthetic process cellular process regulation of DNA-templated transcription macromolecule metabolic process regulation of metabolic process auxin-activated signaling pathway cellular response to stimulus response to organic substance response to stimulus signaling response to endogenous stimulus hormone-mediated signaling pathway cellular response to auxin stimulus cell communication response to auxin cellular response to endogenous stimulus cellular response to chemical stimulus response to hormone response to chemical cellular response to organic substance signal transduction cellular response to hormone stimulus	membrane-bounded organelle intracellular organelle intracellular anatomical structure organelle nucleus intracellular membrane-bounded organelle cellular anatomical entity
C	21-7_A	-	-	-
D	21-7_B	-	-	-

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B	IPR033389	AUX/IAA domain	Domain
A, B	IPR015300	DNA-binding pseudobarrel domain superfamily	Homologous Superfamily
A, B	IPR003340	B3 DNA binding domain	Domain
A, B	IPR044835	Auxin response factor	Family
A, B	IPR010525	Auxin response factor domain	Domain
A, B	IPR000270	PB1 domain	Domain

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.