Annotations: 6S9F

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B	PF07679	Immunoglobulin I-set domain (I-set)	Immunoglobulin I-set domain	-	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B	Tyrosine-protein kinase-like otk	cell adhesion molecule binding protein binding binding protein heterodimerization activity protein dimerization activity molecular transducer activity catalytic activity, acting on a protein kinase activity protein kinase activity signaling receptor activity transferase activity phosphotransferase activity, alcohol group as acceptor transferase activity, transferring phosphorus-containing groups protein tyrosine kinase activity cell adhesion molecule binding protein binding binding protein heterodimerization activity protein dimerization activity molecular transducer activity catalytic activity, acting on a protein kinase activity protein kinase activity signaling receptor activity transferase activity phosphotransferase activity, alcohol group as acceptor transferase activity, transferring phosphorus-containing groups protein tyrosine kinase activity transmembrane receptor protein tyrosine kinase activity transmembrane receptor protein kinase activity transmembrane signaling receptor activity catalytic activity adenyl ribonucleotide binding nucleotide binding purine ribonucleotide binding purine ribonucleoside triphosphate binding nucleoside phosphate binding ion binding purine nucleotide binding organic cyclic compound binding anion binding adenyl nucleotide binding ATP binding heterocyclic compound binding carbohydrate derivative binding ribonucleotide binding small molecule binding cell adhesion mediator activity cell-cell adhesion mediator activity identical protein binding protein homodimerization activity semaphorin receptor binding signaling receptor binding Wnt-protein binding	cellular response to stimulus regulation of biological process regulation of signaling regulation of cellular process cell surface receptor signaling pathway response to stimulus regulation of Wnt signaling pathway signaling regulation of canonical Wnt signaling pathway canonical Wnt signaling pathway biological regulation regulation of signal transduction cell communication regulation of response to stimulus cellular response to stimulus regulation of biological process regulation of signaling regulation of cellular process cell surface receptor signaling pathway response to stimulus regulation of Wnt signaling pathway signaling regulation of canonical Wnt signaling pathway canonical Wnt signaling pathway biological regulation regulation of signal transduction cell communication regulation of response to stimulus regulation of cell communication cellular process signal transduction Wnt signaling pathway multicellular organismal process axonogenesis cellular developmental process cell projection organization plasma membrane bounded cell projection morphogenesis cell development neuron projection development cell morphogenesis cellular component organization neurogenesis multicellular organism development cell projection morphogenesis neuron differentiation neuron projection morphogenesis cell differentiation anatomical structure development cellular component organization or biogenesis system development developmental process plasma membrane bounded cell projection organization axon guidance nervous system development axon development cell morphogenesis involved in neuron differentiation generation of neurons anatomical structure morphogenesis neuron projection guidance neuron development retinal ganglion cell axon guidance negative regulation of signaling negative regulation of biological process negative regulation of cell communication negative regulation of Wnt signaling pathway negative regulation of cellular process negative regulation of response to stimulus negative regulation of signal transduction negative regulation of canonical Wnt signaling pathway genitalia development reproductive system development reproductive process sex differentiation animal organ development developmental process involved in reproduction internal genitalia morphogenesis reproductive structure development animal organ morphogenesis genitalia morphogenesis neuron recognition dendrite self-avoidance cell recognition imaginal disc-derived female genitalia morphogenesis imaginal disc morphogenesis female genitalia development genital disc development imaginal disc-derived female genitalia development metamorphosis imaginal disc development instar larval or pupal morphogenesis post-embryonic animal morphogenesis post-embryonic development post-embryonic genitalia morphogenesis female sex differentiation instar larval or pupal development genital disc morphogenesis imaginal disc-derived genitalia development imaginal disc-derived genitalia morphogenesis female genitalia morphogenesis cell adhesion cell-cell adhesion cell-cell adhesion via plasma-membrane adhesion molecules homophilic cell adhesion via plasma membrane adhesion molecules male genitalia morphogenesis male anatomical structure morphogenesis male sex differentiation male genitalia development imaginal disc-derived male genitalia morphogenesis imaginal disc-derived male genitalia development photoreceptor cell axon guidance	membrane cellular anatomical entity cell periphery plasma membrane axon cell projection neuron projection plasma membrane bounded cell projection

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B	IPR036179	Immunoglobulin-like domain superfamily	Homologous Superfamily
A, B	IPR003599	Immunoglobulin subtype	Domain
A, B	IPR003598	Immunoglobulin subtype 2	Domain
A, B	IPR008266	Tyrosine-protein kinase, active site	Active Site
A, B	IPR020635	Tyrosine-protein kinase, catalytic domain	Domain
A, B	IPR000719	Protein kinase domain	Domain
A, B	IPR001245	Serine-threonine/tyrosine-protein kinase, catalytic domain	Domain
A, B	IPR013098	Immunoglobulin I-set	Domain
A, B	IPR011009	Protein kinase-like domain superfamily	Homologous Superfamily
A, B	IPR013783	Immunoglobulin-like fold	Homologous Superfamily
A, B	IPR007110	Immunoglobulin-like domain	Domain

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.