6PH3

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	PF08447	e6ph3A2	A: a+b three layers	X: Profilin-like	H: sensor domains (From Topology)	T: sensor domains	F: PF08447	ECOD (1.6)
A	PF13426	e6ph3A1	A: a+b three layers	X: Profilin-like	H: sensor domains (From Topology)	T: sensor domains	F: PF13426	ECOD (1.6)
B	PF08447	e6ph3B2	A: a+b three layers	X: Profilin-like	H: sensor domains (From Topology)	T: sensor domains	F: PF08447	ECOD (1.6)
B	PF13426	e6ph3B1	A: a+b three layers	X: Profilin-like	H: sensor domains (From Topology)	T: sensor domains	F: PF13426	ECOD (1.6)
C	PF08447	e6ph3C2	A: a+b three layers	X: Profilin-like	H: sensor domains (From Topology)	T: sensor domains	F: PF08447	ECOD (1.6)
C	PF13426	e6ph3C1	A: a+b three layers	X: Profilin-like	H: sensor domains (From Topology)	T: sensor domains	F: PF13426	ECOD (1.6)
D	PF08447	e6ph3D2	A: a+b three layers	X: Profilin-like	H: sensor domains (From Topology)	T: sensor domains	F: PF08447	ECOD (1.6)
D	PF13426	e6ph3D1	A: a+b three layers	X: Profilin-like	H: sensor domains (From Topology)	T: sensor domains	F: PF13426	ECOD (1.6)

Chains	Accession	Name	Description	Comments	Source
A, B, C, D	PF13426	PAS domain (PAS_9)	PAS domain	This domain is found in many signalling proteins in which it functions as a sensor domain. It recognises FMN, Zn(II), FAD and riboflavin (MAtilla et. al., FEMS Microbiology Reviews, fuab043, 45, 2021, 1. https://doi.org/10.1093/femsre/fuab043).	Domain
A, B, C, D	PF08447	PAS fold (PAS_3)	PAS fold	The PAS fold corresponds to the structural domain that has previously been defined as PAS and PAC motifs [4]. The PAS fold appears in archaea, eubacteria and eukarya.	Domain

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B, C, D	Blue-light-activated histidine kinase	binding adenyl ribonucleotide binding nucleotide binding purine ribonucleotide binding purine ribonucleoside triphosphate binding nucleoside phosphate binding ion binding purine nucleotide binding organic cyclic compound binding anion binding adenyl nucleotide binding ATP binding heterocyclic compound binding carbohydrate derivative binding binding adenyl ribonucleotide binding nucleotide binding purine ribonucleotide binding purine ribonucleoside triphosphate binding nucleoside phosphate binding ion binding purine nucleotide binding organic cyclic compound binding anion binding adenyl nucleotide binding ATP binding heterocyclic compound binding carbohydrate derivative binding ribonucleotide binding small molecule binding catalytic activity, acting on a protein kinase activity protein kinase activity transferase activity catalytic activity phosphotransferase activity, nitrogenous group as acceptor phosphotransferase activity, alcohol group as acceptor protein histidine kinase activity transferase activity, transferring phosphorus-containing groups molecular transducer activity photoreceptor activity signaling receptor activity	response to stimulus	-

Chains	Accession	Name	Type
A, B, C, D	IPR035965	PAS domain superfamily	Homologous Superfamily
A, B, C, D	IPR001610	PAC motif	Repeat
A, B, C, D	IPR000700	PAS-associated, C-terminal	Domain
A, B, C, D	IPR013655	PAS fold-3	Domain
A, B, C, D	IPR000014	PAS domain	Domain
A, B, C, D	IPR011102	Signal transduction histidine kinase, HWE region	Domain