6OH2

X-ray crystal structure of the mouse CMP-sialic acid transporter in complex with CMP, by lipidic cubic phase

External Resource: Annotation

Domain Annotation: ECOD Classification
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification
Membrane Protein Annotation: PDBTM
Membrane Protein Annotation: MemProtMD
Membrane Protein Annotation: mpstruc

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	PF04142	e6oh2A1	A: alpha bundles	X: Drug/Metabolite transporter (From Topology)	H: Drug/Metabolite transporter (From Topology)	T: Drug/Metabolite transporter	F: PF04142	ECOD (1.6)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A	PF04142	Nucleotide-sugar transporter (Nuc_sug_transp)	Nucleotide-sugar transporter	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A	CMP-sialic acid transporter	antiporter activity active transmembrane transporter activity transporter activity transmembrane transporter activity secondary active transmembrane transporter activity carbohydrate derivative transmembrane transporter activity pyrimidine nucleotide-sugar transmembrane transporter activity nucleobase-containing compound transmembrane transporter activity CMP-N-acetylneuraminate transmembrane transporter activity nucleotide-sugar transmembrane transporter activity organic anion transmembrane transporter activity	localization transport organic substance transport carbohydrate transport establishment of localization CMP-N-acetylneuraminate transmembrane transport nitrogen compound transport organic anion transport carbohydrate derivative transport pyrimidine nucleotide-sugar transmembrane transport transmembrane transport nucleotide-sugar transmembrane transport cellular process nucleobase-containing compound transport	membrane cellular anatomical entity membrane-bounded organelle Golgi membrane intracellular anatomical structure Golgi apparatus intracellular membrane-bounded organelle endomembrane system intracellular organelle bounding membrane of organelle organelle cytoplasm organelle membrane

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A	IPR007271	Nucleotide-sugar transporter	Family

Membrane Protein Annotation: PDBTM PDBTM Database Homepage

Chains	External Link	Comment
A	PDBTM	Annotated as membrane protein by PDBTM

Membrane Protein Annotation: MemProtMD MemProtMD Database Homepage

Chains	External Link	Comment
A	MemProtMD	Annotated as membrane protein by MemProtMD

Membrane Protein Annotation: mpstruc mpstruc Database Homepage

Chains	Resource Link	Group	Subgroup	Protein
A	mpstruc	TRANSMEMBRANE PROTEINS: ALPHA-HELICAL	Solute Carrier (SLC) Transporter Superfamily	SLC35 superfamily CMP-sialic acid (CMP-Sia) transporter in complex with CMP, lipidic cubic phase xtals

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.