6MU0

Crystal Structure of Ribose-5-phosphate Isomerase B from Mycoplasma genitalium with bound Ribulose-5-phosphate

External Resource: Annotation

Domain Annotation: SCOP/SCOPe Classification
Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification
Protein Modification Annotation

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A	d6mu0a1	Alpha and beta proteins (a/b)	Ribose/Galactose isomerase RpiB/AlsB	Ribose/Galactose isomerase RpiB/AlsB	automated matches	automated matches	(Mycoplasmoides genitalium G37 ) [TaxId: 243273 ],	SCOPe (2.08)
A	d6mu0a2	Artifacts	Tags	Tags	Tags	N-terminal Tags	(Mycoplasmoides genitalium G37 ) [TaxId: 243273 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2 Family	Ribose/Galactose isomerase RpiB/AlsB	8080549	4000476	SCOP2 (2022-06-29)
A	SCOP2 Superfamily	Ribose/Galactose isomerase RpiB/AlsB	8080550	3000383	SCOP2 (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	LacAB_rpiB	e6mu0A1	A: a/b three-layered sandwiches	X: Ribose/Galactose isomerase RpiB/AlsB (From Topology)	H: Ribose/Galactose isomerase RpiB/AlsB (From Topology)	T: Ribose/Galactose isomerase RpiB/AlsB	F: LacAB_rpiB	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	3.40.1400.10	Alpha Beta	3-Layer(aba) Sandwich	Ribose 5-phosphate Isomerase B	Chain: A,	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A	PF02502	Ribose/Galactose Isomerase (LacAB_rpiB)	Ribose/Galactose Isomerase	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A	Probable ribose-5-phosphate isomerase B	isomerase activity intramolecular oxidoreductase activity, interconverting aldoses and ketoses intramolecular oxidoreductase activity ribose-5-phosphate isomerase activity catalytic activity	monosaccharide metabolic process carbohydrate metabolic process catabolic process hexose catabolic process carbohydrate catabolic process hexose metabolic process primary metabolic process D-allose metabolic process organic substance metabolic process small molecule metabolic process metabolic process D-allose catabolic process monosaccharide catabolic process small molecule catabolic process monosaccharide metabolic process carbohydrate metabolic process catabolic process hexose catabolic process carbohydrate catabolic process hexose metabolic process primary metabolic process D-allose metabolic process organic substance metabolic process small molecule metabolic process metabolic process D-allose catabolic process monosaccharide catabolic process small molecule catabolic process organic substance catabolic process ribose phosphate metabolic process carbohydrate derivative metabolic process glyceraldehyde-3-phosphate metabolic process glucose 6-phosphate metabolic process nucleobase-containing compound metabolic process purine nucleotide metabolic process nucleobase-containing small molecule metabolic process cellular aldehyde metabolic process pentose-phosphate shunt phosphate-containing compound metabolic process pyridine-containing compound metabolic process phosphorus metabolic process pyridine nucleotide metabolic process nucleoside phosphate metabolic process nicotinamide nucleotide metabolic process organonitrogen compound metabolic process cellular metabolic process generation of precursor metabolites and energy nucleotide metabolic process purine-containing compound metabolic process NADP metabolic process organic cyclic compound metabolic process NADPH regeneration organophosphate metabolic process cellular process pentose-phosphate shunt, non-oxidative branch	-

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A	IPR036569	Sugar-phosphate isomerase, RpiB/LacA/LacB superfamily	Homologous Superfamily
A	IPR003500	Sugar-phosphate isomerase, RpiB/LacA/LacB family	Family
A	IPR004785	Ribose 5-phosphate isomerase B	Family

Protein Modification Annotation

Modified Residue(s)
Chain	Residue(s)	Description
A	CSD	Parent Component: CYS RESID: AA0262 PSI-MOD : L-cysteine sulfinic acid MOD:00267

RCSB PDB Core Operations are funded by the National Science Foundation (DBI-1832184), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.