6MNZ

Crystal structure of RibBX, a two domain 3,4-dihydroxy-2-butanone 4-phosphate synthase from A. baumannii.

External Resource: Annotation

Domain Annotation: ECOD Classification
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	PF00926	e6mnzA2	A: a+b complex topology	X: YrdC/RibB (From Topology)	H: YrdC/RibB (From Topology)	T: YrdC/RibB	F: PF00926	ECOD (1.6)
A	PF00925	e6mnzA1	A: a/b three-layered sandwiches	X: RibA-like (From Topology)	H: RibA-like (From Topology)	T: RibA-like	F: PF00925	ECOD (1.6)
B	PF00926	e6mnzB1	A: a+b complex topology	X: YrdC/RibB (From Topology)	H: YrdC/RibB (From Topology)	T: YrdC/RibB	F: PF00926	ECOD (1.6)
B	PF00925	e6mnzB2	A: a/b three-layered sandwiches	X: RibA-like (From Topology)	H: RibA-like (From Topology)	T: RibA-like	F: PF00925	ECOD (1.6)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B	PF00925	GTP cyclohydrolase II (GTP_cyclohydro2)	GTP cyclohydrolase II	-	Family
A, B	PF00926	3,4-dihydroxy-2-butanone 4-phosphate synthase (DHBP_synthase)	3,4-dihydroxy-2-butanone 4-phosphate synthase	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B	3,4-dihydroxy-2-butanone 4-phosphate synthase	cation binding magnesium ion binding ion binding binding metal ion binding small molecule binding manganese ion binding transition metal ion binding hydrolase activity catalytic activity lyase activity 3,4-dihydroxy-2-butanone-4-phosphate synthase activity carbon-carbon lyase activity	organonitrogen compound metabolic process water-soluble vitamin biosynthetic process small molecule biosynthetic process cellular biosynthetic process flavin-containing compound metabolic process cellular metabolic process organonitrogen compound biosynthetic process vitamin biosynthetic process riboflavin biosynthetic process vitamin metabolic process organic cyclic compound metabolic process flavin-containing compound biosynthetic process organic substance metabolic process biosynthetic process organic cyclic compound biosynthetic process organonitrogen compound metabolic process water-soluble vitamin biosynthetic process small molecule biosynthetic process cellular biosynthetic process flavin-containing compound metabolic process cellular metabolic process organonitrogen compound biosynthetic process vitamin biosynthetic process riboflavin biosynthetic process vitamin metabolic process organic cyclic compound metabolic process flavin-containing compound biosynthetic process organic substance metabolic process biosynthetic process organic cyclic compound biosynthetic process organic substance biosynthetic process metabolic process small molecule metabolic process cellular process water-soluble vitamin metabolic process riboflavin metabolic process	-

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B	IPR017945	DHBP synthase RibB-like alpha/beta domain superfamily	Homologous Superfamily
A, B	IPR000422	3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB	Family
A, B	IPR032677	GTP cyclohydrolase II	Domain
A, B	IPR036144	GTP cyclohydrolase II superfamily	Homologous Superfamily

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.