Annotations: 6MJF

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	F_UNCLASSIFIED	e6mjfA1	A: alpha bundles	X: all-alpha NTP pyrophosphatases (From Homology)	H: all-alpha NTP pyrophosphatases	T: Hypothetical protein AF_0060	F: F_UNCLASSIFIED	ECOD (1.6)
A	F_UNCLASSIFIED	e6mjfA3	A: a+b two layers	X: Tetrapyrrole methylase C-terminal domain-like	H: Tetrapyrrole methylase C-terminal domain (From Topology)	T: Tetrapyrrole methylase C-terminal domain	F: F_UNCLASSIFIED	ECOD (1.6)
A	PF00590	e6mjfA2	A: a/b three-layered sandwiches	X: Tetrapyrrole methylase N-terminal domain (From Topology)	H: Tetrapyrrole methylase N-terminal domain (From Topology)	T: Tetrapyrrole methylase N-terminal domain	F: PF00590	ECOD (1.6)
B	F_UNCLASSIFIED	e6mjfB2	A: alpha bundles	X: all-alpha NTP pyrophosphatases (From Homology)	H: all-alpha NTP pyrophosphatases	T: Hypothetical protein AF_0060	F: F_UNCLASSIFIED	ECOD (1.6)
B	F_UNCLASSIFIED	e6mjfB1	A: a+b two layers	X: Tetrapyrrole methylase C-terminal domain-like	H: Tetrapyrrole methylase C-terminal domain (From Topology)	T: Tetrapyrrole methylase C-terminal domain	F: F_UNCLASSIFIED	ECOD (1.6)
B	PF00590	e6mjfB3	A: a/b three-layered sandwiches	X: Tetrapyrrole methylase N-terminal domain (From Topology)	H: Tetrapyrrole methylase N-terminal domain (From Topology)	T: Tetrapyrrole methylase N-terminal domain	F: PF00590	ECOD (1.6)
C	F_UNCLASSIFIED	e6mjfC3	A: alpha bundles	X: all-alpha NTP pyrophosphatases (From Homology)	H: all-alpha NTP pyrophosphatases	T: Hypothetical protein AF_0060	F: F_UNCLASSIFIED	ECOD (1.6)
C	F_UNCLASSIFIED	e6mjfC2	A: a+b two layers	X: Tetrapyrrole methylase C-terminal domain-like	H: Tetrapyrrole methylase C-terminal domain (From Topology)	T: Tetrapyrrole methylase C-terminal domain	F: F_UNCLASSIFIED	ECOD (1.6)
C	PF00590	e6mjfC1	A: a/b three-layered sandwiches	X: Tetrapyrrole methylase N-terminal domain (From Topology)	H: Tetrapyrrole methylase N-terminal domain (From Topology)	T: Tetrapyrrole methylase N-terminal domain	F: PF00590	ECOD (1.6)
D	F_UNCLASSIFIED	e6mjfD3	A: alpha bundles	X: all-alpha NTP pyrophosphatases (From Homology)	H: all-alpha NTP pyrophosphatases	T: Hypothetical protein AF_0060	F: F_UNCLASSIFIED	ECOD (1.6)
D	F_UNCLASSIFIED	e6mjfD2	A: a+b two layers	X: Tetrapyrrole methylase C-terminal domain-like	H: Tetrapyrrole methylase C-terminal domain (From Topology)	T: Tetrapyrrole methylase C-terminal domain	F: F_UNCLASSIFIED	ECOD (1.6)
D	PF00590	e6mjfD1	A: a/b three-layered sandwiches	X: Tetrapyrrole methylase N-terminal domain (From Topology)	H: Tetrapyrrole methylase N-terminal domain (From Topology)	T: Tetrapyrrole methylase N-terminal domain	F: PF00590	ECOD (1.6)
E	F_UNCLASSIFIED	e6mjfE3	A: alpha bundles	X: all-alpha NTP pyrophosphatases (From Homology)	H: all-alpha NTP pyrophosphatases	T: Hypothetical protein AF_0060	F: F_UNCLASSIFIED	ECOD (1.6)
E	F_UNCLASSIFIED	e6mjfE1	A: a+b two layers	X: Tetrapyrrole methylase C-terminal domain-like	H: Tetrapyrrole methylase C-terminal domain (From Topology)	T: Tetrapyrrole methylase C-terminal domain	F: F_UNCLASSIFIED	ECOD (1.6)
E	PF00590	e6mjfE2	A: a/b three-layered sandwiches	X: Tetrapyrrole methylase N-terminal domain (From Topology)	H: Tetrapyrrole methylase N-terminal domain (From Topology)	T: Tetrapyrrole methylase N-terminal domain	F: PF00590	ECOD (1.6)
F	F_UNCLASSIFIED	e6mjfF3	A: alpha bundles	X: all-alpha NTP pyrophosphatases (From Homology)	H: all-alpha NTP pyrophosphatases	T: Hypothetical protein AF_0060	F: F_UNCLASSIFIED	ECOD (1.6)
F	F_UNCLASSIFIED	e6mjfF2	A: a+b two layers	X: Tetrapyrrole methylase C-terminal domain-like	H: Tetrapyrrole methylase C-terminal domain (From Topology)	T: Tetrapyrrole methylase C-terminal domain	F: F_UNCLASSIFIED	ECOD (1.6)
F	PF00590	e6mjfF1	A: a/b three-layered sandwiches	X: Tetrapyrrole methylase N-terminal domain (From Topology)	H: Tetrapyrrole methylase N-terminal domain (From Topology)	T: Tetrapyrrole methylase N-terminal domain	F: PF00590	ECOD (1.6)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B, C, D, E A, B, C, D, E, F	PF00590	Tetrapyrrole (Corrin/Porphyrin) Methylases (TP_methylase)	Tetrapyrrole (Corrin/Porphyrin) Methylases	This family uses S-AdoMet in the methylation of diverse substrates. This family includes a related group of bacterial proteins of unknown function, including Swiss:P45528. This family includes the methylase Dipthine synthase.	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B, C, D, E A, B, C, D, E, F	dbOphM	transferase activity, transferring one-carbon groups transferase activity methyltransferase activity catalytic activity	methylation metabolic process	-

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B, C, D, E A, B, C, D, E, F	IPR035996	Tetrapyrrole methylase superfamily	Homologous Superfamily
A, B, C, D, E A, B, C, D, E, F	IPR014777	Tetrapyrrole methylase, subdomain 1	Homologous Superfamily
A, B, C, D, E A, B, C, D, E, F	IPR000878	Tetrapyrrole methylase	Domain

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.