6LO8
Cryo-EM structure of the TIM22 complex from yeast
External Resource: Annotation
- Domain Annotation: SCOP2 Classification
- Domain Annotation: ECOD Classification
- Protein Family Annotation
- Gene Ontology: Gene Product Annotation
- InterPro: Protein Family Classification
- Membrane Protein Annotation: OPM
- Membrane Protein Annotation: PDBTM
- Membrane Protein Annotation: MemProtMD
- Membrane Protein Annotation: mpstruc
Domain Annotation: ECOD Classification ECOD Database Homepage
Chains | Family Name | Domain Identifier | Architecture | Possible Homology | Homology | Topology | Family | Provenance Source (Version) |
---|---|---|---|---|---|---|---|---|
C | PF01127 | e6lo8C1 | A: alpha bundles | X: Transmembrane heme-binding four-helical bundle (From Homology) | H: Transmembrane heme-binding four-helical bundle | T: Fumarate reductase respiratory complex transmembrane subunits | F: PF01127 | ECOD (1.6) |
D | PF05328 | e6lo8D1 | A: alpha bundles | X: Transmembrane heme-binding four-helical bundle (From Homology) | H: Transmembrane heme-binding four-helical bundle | T: Fumarate reductase respiratory complex transmembrane subunits | F: PF05328 | ECOD (1.6) |
E | PF02953 | e6lo8E1 | A: few secondary structure elements | X: Tim10/DDP (From Topology) | H: Tim10/DDP (From Topology) | T: Tim10/DDP | F: PF02953 | ECOD (1.6) |
G | PF02953 | e6lo8G1 | A: few secondary structure elements | X: Tim10/DDP (From Topology) | H: Tim10/DDP (From Topology) | T: Tim10/DDP | F: PF02953 | ECOD (1.6) |
I | PF02953 | e6lo8I1 | A: few secondary structure elements | X: Tim10/DDP (From Topology) | H: Tim10/DDP (From Topology) | T: Tim10/DDP | F: PF02953 | ECOD (1.6) |
F | PF02953 | e6lo8F1 | A: few secondary structure elements | X: Tim10/DDP (From Topology) | H: Tim10/DDP (From Topology) | T: Tim10/DDP | F: PF02953 | ECOD (1.6) |
H | PF02953 | e6lo8H1 | A: few secondary structure elements | X: Tim10/DDP (From Topology) | H: Tim10/DDP (From Topology) | T: Tim10/DDP | F: PF02953 | ECOD (1.6) |
J | PF02953 | e6lo8J1 | A: few secondary structure elements | X: Tim10/DDP (From Topology) | H: Tim10/DDP (From Topology) | T: Tim10/DDP | F: PF02953 | ECOD (1.6) |
Protein Family Annotation Pfam Database Homepage
Chains | Accession | Name | Description | Comments | Source |
---|---|---|---|---|---|
PF02466 | Tim17/Tim22/Tim23/Pmp24 family (Tim17) | Tim17/Tim22/Tim23/Pmp24 family | - | Family | |
PF11711 | Inner membrane protein import complex subunit Tim54 (Tim54) | Inner membrane protein import complex subunit Tim54 | - | Family | |
PF01127 | Succinate dehydrogenase/Fumarate reductase transmembrane subunit (Sdh_cyt) | Succinate dehydrogenase/Fumarate reductase transmembrane subunit | - | Family | |
PF05328 | CybS, succinate dehydrogenase cytochrome B small subunit (CybS) | CybS, succinate dehydrogenase cytochrome B small subunit | - | Family | |
PF02953 | Tim10/DDP family zinc finger (zf-Tim10_DDP) | Tim10/DDP family zinc finger | Putative zinc binding domain with four conserved cysteine residues. This domain is found in the human disease protein Swiss:O60220. Members of this family such as Tim9 and Tim10 are involved in mitochondrial protein import [1]. Members of thi ... | Domain | |
PF02953 | Tim10/DDP family zinc finger (zf-Tim10_DDP) | Tim10/DDP family zinc finger | Putative zinc binding domain with four conserved cysteine residues. This domain is found in the human disease protein Swiss:O60220. Members of this family such as Tim9 and Tim10 are involved in mitochondrial protein import [1]. Members of thi ... | Domain | |
PF02953 | Tim10/DDP family zinc finger (zf-Tim10_DDP) | Tim10/DDP family zinc finger | Putative zinc binding domain with four conserved cysteine residues. This domain is found in the human disease protein Swiss:O60220. Members of this family such as Tim9 and Tim10 are involved in mitochondrial protein import [1]. Members of thi ... | Domain |
Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage
InterPro: Protein Family Classification InterPro Database Homepage
Chains | Accession | Name | Type |
---|---|---|---|
IPR039175 | Mitochondrial import inner membrane translocase subunit TIM22 | Family | |
IPR021056 | Mitochondrial import inner membrane translocase subunit Tim54 | Family | |
IPR034804 | Fumarate reductase/succinate dehydrogenase, transmembrane subunit | Homologous Superfamily | |
IPR014314 | Succinate dehydrogenase, cytochrome b556 subunit | Family | |
IPR018495 | Succinate dehydrogenase, cytochrome b subunit, conserved site | Conserved Site | |
IPR000701 | Succinate dehydrogenase/fumarate reductase type B, transmembrane subunit | Family | |
IPR034804 | Fumarate reductase/succinate dehydrogenase, transmembrane subunit | Homologous Superfamily | |
IPR007992 | Succinate dehydrogenase [ubiquinone] cytochrome b small subunit, CybS | Family | |
IPR004217 | Tim10-like | Domain | |
IPR035427 | Tim10-like domain superfamily | Homologous Superfamily | |
IPR004217 | Tim10-like | Domain | |
IPR035427 | Tim10-like domain superfamily | Homologous Superfamily | |
IPR004217 | Tim10-like | Domain | |
IPR035427 | Tim10-like domain superfamily | Homologous Superfamily |
Membrane Protein Annotation: OPM OPM Database Homepage
Chains | External Link | Type | Class | Superfamily | Family |
---|---|---|---|---|---|
OPM | Transmembrane | Alpha-helical polytopic | Mitochondrial and chloroplast protein translocases | TIM complex |
Membrane Protein Annotation: PDBTM PDBTM Database Homepage
Membrane Protein Annotation: MemProtMD MemProtMD Database Homepage
Membrane Protein Annotation: mpstruc mpstruc Database Homepage
Chains | Resource Link | Group | Subgroup | Protein |
---|---|---|---|---|
mpstruc | TRANSMEMBRANE PROTEINS: ALPHA-HELICAL | Sec, Translocase, and Insertase Proteins | TIM22 complex from mitochondrial inner membrane |