6LL7

Type II inorganic pyrophosphatase (PPase) from the psychrophilic bacterium Shewanella sp. AS-11, Mn-activated form

External Resource: Annotation

Domain Annotation: SCOP/SCOPe Classification
Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A	d6ll7a_	Alpha and beta proteins (a/b)	DHH phosphoesterases	DHH phosphoesterases	automated matches	automated matches	(Shewanella sp. AS-11 ) [TaxId: 912551 ],	SCOPe (2.08)
B	d6ll7b_	Alpha and beta proteins (a/b)	DHH phosphoesterases	DHH phosphoesterases	automated matches	automated matches	(Shewanella sp. AS-11 ) [TaxId: 912551 ],	SCOPe (2.08)
C	d6ll7c_	Alpha and beta proteins (a/b)	DHH phosphoesterases	DHH phosphoesterases	automated matches	automated matches	(Shewanella sp. AS-11 ) [TaxId: 912551 ],	SCOPe (2.08)
D	d6ll7d_	Alpha and beta proteins (a/b)	DHH phosphoesterases	DHH phosphoesterases	automated matches	automated matches	(Shewanella sp. AS-11 ) [TaxId: 912551 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2B Superfamily	DHH phosphoesterases	8098046	3000896	SCOP2B (2022-06-29)
B	SCOP2B Superfamily	DHH phosphoesterases	8098046	3000896	SCOP2B (2022-06-29)
C	SCOP2B Superfamily	DHH phosphoesterases	8098046	3000896	SCOP2B (2022-06-29)
D	SCOP2 Family	Manganese-dependent inorganic pyrophosphatase (family II)	8098045	4003453	SCOP2 (2022-06-29)
D	SCOP2 Superfamily	DHH phosphoesterases	8098046	3000896	SCOP2 (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	PF02833	e6ll7A2	A: a+b three layers	X: C-terminal domain in DHH phosphoesterases (From Topology)	H: C-terminal domain in DHH phosphoesterases (From Topology)	T: C-terminal domain in DHH phosphoesterases	F: PF02833	ECOD (1.6)
A	PF01368	e6ll7A1	A: a/b three-layered sandwiches	X: HAD domain-like	H: HAD domain-related	T: DHH phosphoesterases	F: PF01368	ECOD (1.6)
B	PF02833	e6ll7B1	A: a+b three layers	X: C-terminal domain in DHH phosphoesterases (From Topology)	H: C-terminal domain in DHH phosphoesterases (From Topology)	T: C-terminal domain in DHH phosphoesterases	F: PF02833	ECOD (1.6)
B	PF01368	e6ll7B2	A: a/b three-layered sandwiches	X: HAD domain-like	H: HAD domain-related	T: DHH phosphoesterases	F: PF01368	ECOD (1.6)
C	PF02833	e6ll7C2	A: a+b three layers	X: C-terminal domain in DHH phosphoesterases (From Topology)	H: C-terminal domain in DHH phosphoesterases (From Topology)	T: C-terminal domain in DHH phosphoesterases	F: PF02833	ECOD (1.6)
C	PF01368	e6ll7C1	A: a/b three-layered sandwiches	X: HAD domain-like	H: HAD domain-related	T: DHH phosphoesterases	F: PF01368	ECOD (1.6)
D	PF02833	e6ll7D1	A: a+b three layers	X: C-terminal domain in DHH phosphoesterases (From Topology)	H: C-terminal domain in DHH phosphoesterases (From Topology)	T: C-terminal domain in DHH phosphoesterases	F: PF02833	ECOD (1.6)
D	PF01368	e6ll7D2	A: a/b three-layered sandwiches	X: HAD domain-like	H: HAD domain-related	T: DHH phosphoesterases	F: PF01368	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	3.90.1640.10	Alpha Beta	Alpha-Beta Complex	inorganic pyrophosphatase (n-terminal core)	inorganic pyrophosphatase (n-terminal core)	CATH (utative)
A	3.10.310.20	Alpha Beta	Roll	Diaminopimelate Epimerase	Chain A, domain 1	CATH (utative)
B	3.90.1640.10	Alpha Beta	Alpha-Beta Complex	inorganic pyrophosphatase (n-terminal core)	inorganic pyrophosphatase (n-terminal core)	CATH (utative)
B	3.10.310.20	Alpha Beta	Roll	Diaminopimelate Epimerase	Chain A, domain 1	CATH (utative)
C	3.90.1640.10	Alpha Beta	Alpha-Beta Complex	inorganic pyrophosphatase (n-terminal core)	inorganic pyrophosphatase (n-terminal core)	CATH (utative)
C	3.10.310.20	Alpha Beta	Roll	Diaminopimelate Epimerase	Chain A, domain 1	CATH (utative)
D	3.90.1640.10	Alpha Beta	Alpha-Beta Complex	inorganic pyrophosphatase (n-terminal core)	inorganic pyrophosphatase (n-terminal core)	CATH (utative)
D	3.10.310.20	Alpha Beta	Roll	Diaminopimelate Epimerase	Chain A, domain 1	CATH (utative)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B, C, D	PF02833	DHHA2 domain (DHHA2)	DHHA2 domain	-	Family
A, B, C, D	PF01368	DHH family (DHH)	DHH family	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B, C, D	Inorganic pyrophosphatase	pyrophosphatase activity hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides hydrolase activity inorganic diphosphate phosphatase activity hydrolase activity, acting on acid anhydrides catalytic activity cation binding ion binding binding metal ion binding small molecule binding	-	intracellular anatomical structure cytoplasm cellular anatomical entity

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B, C, D	IPR001667	DDH domain	Domain
A, B, C, D	IPR004097	DHHA2 domain	Domain
A, B, C, D	IPR038763	DHH phosphoesterase superfamily	Homologous Superfamily
A, B, C, D	IPR038222	DHHA2 domain superfamily	Homologous Superfamily

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.