Annotations: 6L82

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A	PF14609	Gamma-Tubulin ring complex non-core subunit mod21, N-terminal (GCP5-Mod21_N)	Gamma-Tubulin ring complex non-core subunit mod21, N-terminal	GCP5-Mod21 is a non-core subunit of the larger gamma-tubulin ring complex that effects microtubule nucleation from both centrosomal and non-centrosomal sites. This subunit, unlike GCP2 and and GCP3 and others, is not essential for viability in the fi ...	GCP5-Mod21 is a non-core subunit of the larger gamma-tubulin ring complex that effects microtubule nucleation from both centrosomal and non-centrosomal sites. This subunit, unlike GCP2 and and GCP3 and others, is not essential for viability in the fission yeast, and may not be expressed in very high concentrations. Fission yeast can form a large gamma-Tubulin complex C similar to that found in higher eukaryotes and this complex is important for maintaining normal levels of microtubule nucleation in vivo [1,2]. This entry represents the N-terminal domain of Mod21 from fission yeast, which interacts with Mozart1 (Mzt1) which modules gamma-tubulin ring complex (gamma-TRC) assembly and targeting, allowing gamma-TRC to be to be recruited to different microtubule-organising centres [3].	Domain
B	PF12554	Mitotic-spindle organizing gamma-tubulin ring associated (MOZART1)	Mitotic-spindle organizing gamma-tubulin ring associated	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A	Spindle pole body component	cytoskeletal protein binding protein binding binding gamma-tubulin binding tubulin binding	protein polymerization protein-containing complex organization microtubule cytoskeleton organization microtubule polymerization cellular component organization cellular component biogenesis organelle organization microtubule polymerization or depolymerization cellular component assembly microtubule nucleation protein-containing complex assembly cellular process microtubule-based process cellular component organization or biogenesis protein polymerization protein-containing complex organization microtubule cytoskeleton organization microtubule polymerization cellular component organization cellular component biogenesis organelle organization microtubule polymerization or depolymerization cellular component assembly microtubule nucleation protein-containing complex assembly cellular process microtubule-based process cellular component organization or biogenesis supramolecular fiber organization cytoskeleton organization	intracellular organelle intracellular anatomical structure cytoskeleton spindle organelle intracellular non-membrane-bounded organelle spindle pole cellular anatomical entity microtubule cytoskeleton non-membrane-bounded organelle cytoplasm protein-containing complex gamma-tubulin complex microtubule organizing center intracellular organelle intracellular anatomical structure cytoskeleton spindle organelle intracellular non-membrane-bounded organelle spindle pole cellular anatomical entity microtubule cytoskeleton non-membrane-bounded organelle cytoplasm protein-containing complex gamma-tubulin complex microtubule organizing center polymeric cytoskeletal fiber supramolecular fiber microtubule supramolecular polymer supramolecular complex spindle pole body
B	Mozart1	-	gamma-tubulin complex localization localization protein-containing complex localization	protein-containing complex intracellular anatomical structure gamma-tubulin ring complex cellular anatomical entity gamma-tubulin complex intracellular organelle microtubule organizing center cytoskeleton organelle intracellular non-membrane-bounded organelle microtubule cytoskeleton non-membrane-bounded organelle spindle pole body

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A	IPR042241	Gamma-tubulin complex component, C-terminal domain superfamily	Homologous Superfamily
A	IPR032797	Gamma-Tubulin ring complex non-core subunit mod21, N-terminal	Domain
A	IPR007259	Gamma-tubulin complex component protein	Family
A	IPR040457	Gamma tubulin complex component, C-terminal	Domain
A	IPR041470	Gamma tubulin complex component protein, N-terminal	Domain
B	IPR022214	Mitotic-spindle organizing protein 1	Family

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.