Annotations: 6KZ9

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A	PF12357	Phospholipase D C terminal (PLD_C)	Phospholipase D C terminal	-	Family
A	PF00614	Phospholipase D Active site motif (PLDc)	Phospholipase D Active site motif	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A	Phospholipase D alpha 1	cation binding ion binding binding calcium ion binding metal ion binding small molecule binding hydrolase activity, acting on ester bonds hydrolase activity catalytic activity phospholipase activity lipase activity phosphoric ester hydrolase activity phospholipase D activity phosphoric diester hydrolase activity cation binding ion binding binding calcium ion binding metal ion binding small molecule binding hydrolase activity, acting on ester bonds hydrolase activity catalytic activity phospholipase activity lipase activity phosphoric ester hydrolase activity phospholipase D activity phosphoric diester hydrolase activity GTPase regulator activity enzyme regulator activity enzyme activator activity GTPase activator activity molecular function activator activity nucleoside-triphosphatase regulator activity molecular function regulator activity phosphatidylinositol-4,5-bisphosphate binding anion binding phosphatidylinositol bisphosphate binding phospholipid binding lipid binding phosphatidylinositol phosphate binding phosphatidylinositol binding N-acylphosphatidylethanolamine-specific phospholipase D activity	cellular response to stimulus positive regulation of cell communication response to organic substance regulation of cellular process positive regulation of signal transduction response to stimulus response to lipid abscisic acid-activated signaling pathway signaling positive regulation of biological process regulation of signal transduction hormone-mediated signaling pathway cell communication positive regulation of response to stimulus cellular response to endogenous stimulus cellular response to stimulus positive regulation of cell communication response to organic substance regulation of cellular process positive regulation of signal transduction response to stimulus response to lipid abscisic acid-activated signaling pathway signaling positive regulation of biological process regulation of signal transduction hormone-mediated signaling pathway cell communication positive regulation of response to stimulus cellular response to endogenous stimulus response to hormone regulation of cellular response to alcohol cellular response to organic substance signal transduction positive regulation of cellular process cellular response to hormone stimulus cellular response to abscisic acid stimulus regulation of biological process regulation of signaling regulation of response to alcohol response to abscisic acid response to alcohol response to endogenous stimulus biological regulation positive regulation of abscisic acid-activated signaling pathway response to oxygen-containing compound cellular response to oxygen-containing compound cellular response to chemical stimulus cellular response to alcohol regulation of response to stimulus response to chemical cellular response to lipid regulation of cell communication cellular process regulation of abscisic acid-activated signaling pathway positive regulation of signaling regulation of stomatal movement stomatal movement organonitrogen compound metabolic process cellular metabolic process glycerophospholipid metabolic process primary metabolic process phospholipid metabolic process organic substance metabolic process organophosphate metabolic process cellular lipid metabolic process phosphate-containing compound metabolic process phosphatidylcholine metabolic process metabolic process glycerolipid metabolic process phosphorus metabolic process lipid metabolic process developmental process multicellular organism development multicellular organismal process anatomical structure development post-embryonic development seed germination seedling development plant organ development leaf morphogenesis shoot system morphogenesis plant organ morphogenesis anatomical structure morphogenesis leaf shaping leaf development anatomical structure arrangement shoot system development phyllome development system development fatty acid metabolic process oxoacid metabolic process carboxylic acid metabolic process organic acid metabolic process small molecule metabolic process monocarboxylic acid metabolic process lipid catabolic process catabolic process organic substance catabolic process intracellular signal transduction ethylene-activated signaling pathway response to ethylene phosphorelay signal transduction system cellular response to ethylene stimulus	membrane-bounded organelle intracellular organelle intracellular anatomical structure mitochondrion organelle cytoplasm cellular anatomical entity intracellular membrane-bounded organelle membrane intracellular vesicle cytoplasmic vesicle clathrin-coated vesicle coated vesicle vesicle membrane-bounded organelle intracellular organelle intracellular anatomical structure mitochondrion organelle cytoplasm cellular anatomical entity intracellular membrane-bounded organelle membrane intracellular vesicle cytoplasmic vesicle clathrin-coated vesicle coated vesicle vesicle mitochondrial membrane organelle envelope mitochondrial envelope organelle membrane cytosol cell periphery plasma membrane cell-cell junction symplast anchoring junction cell junction plasmodesma plastid chloroplast nucleus vacuole endoplasmic reticulum endomembrane system

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A	IPR001736	Phospholipase D/Transphosphatidylase	Domain
A	IPR000008	C2 domain	Domain
A	IPR024632	Phospholipase D, C-terminal	Domain
A	IPR015679	Phospholipase D family	Family
A	IPR035892	C2 domain superfamily	Homologous Superfamily
A	IPR011402	Phospholipase D, plant	Family

Membrane Protein Annotation: OPM OPM Database Homepage

Chains	External Link	Type	Class	Superfamily	Family
A	OPM	Monotopic/peripheral	Alpha + Beta monotopic/peripheral	Phospholipase D-like	Phospholipase D

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.