Annotations: 6KVG

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2B Superfamily	Cyclin-like	8106447	3000768	SCOP2B (2022-06-29)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A	PF05460	Origin recognition complex subunit 6 (ORC6) (ORC6)	Origin recognition complex subunit 6 (ORC6)	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A	Origin recognition complex subunit 6	DNA binding binding organic cyclic compound binding nucleic acid binding	DNA-templated DNA replication DNA replication initiation primary metabolic process DNA metabolic process nucleic acid metabolic process nucleobase-containing compound metabolic process organic cyclic compound metabolic process DNA replication organic substance metabolic process metabolic process macromolecule metabolic process	intracellular anatomical structure cytoplasm cellular anatomical entity cytosol intracellular organelle protein-containing complex origin recognition complex organelle intracellular non-membrane-bounded organelle chromosome non-membrane-bounded organelle membrane-bounded organelle nucleus membrane-enclosed lumen intracellular anatomical structure cytoplasm cellular anatomical entity cytosol intracellular organelle protein-containing complex origin recognition complex organelle intracellular non-membrane-bounded organelle chromosome non-membrane-bounded organelle membrane-bounded organelle nucleus membrane-enclosed lumen intracellular membrane-bounded organelle nucleolus intracellular organelle lumen organelle lumen fibrillar center nuclear lumen membrane nucleoplasm nuclear origin of replication recognition complex nuclear protein-containing complex nuclear chromosome

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A	IPR020529	Origin recognition complex, subunit 6, metazoa/plant	Family
A	IPR008721	Origin recognition complex, subunit 6	Family

Pharos: Disease Associations Pharos Homepage Annotation

Chains	Drug Target	Associated Disease
A	Pharos: Q9Y5N6	Meier-Gorlin syndrome Meier-Gorlin syndrome 3 adrenal cortex carcinoma EAR, PATELLA, SHORT STATURE SYNDROME lung adenocarcinoma malignant mesothelioma pancreatic intraductal papillary-mucinous carcinoma psoriasis breast cancer intellectual disability lung cancer medulloblastoma microcephaly pancreatic intraductal papillary-mucinous neoplasm ductal breast carcinoma in situ Meier-Gorlin syndrome Meier-Gorlin syndrome 3 adrenal cortex carcinoma EAR, PATELLA, SHORT STATURE SYNDROME lung adenocarcinoma malignant mesothelioma pancreatic intraductal papillary-mucinous carcinoma psoriasis breast cancer intellectual disability lung cancer medulloblastoma microcephaly pancreatic intraductal papillary-mucinous neoplasm ductal breast carcinoma in situ invasive ductal breast carcinoma malignant colon neoplasm non-small cell lung carcinoma

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.