6KV2

Crystal structure of trypsin inhibitor 1 from Senna obtusifolia

External Resource: Annotation

Domain Annotation: SCOP/SCOPe Classification
Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A	d6kv2a1	All beta proteins	beta-Trefoil	STI-like	automated matches	automated matches	(Senna obtusifolia ) [TaxId: 346985 ],	SCOPe (2.08)
A	d6kv2a2	Artifacts	Tags	Tags	Tags	N-terminal Tags	(Senna obtusifolia ) [TaxId: 346985 ],	SCOPe (2.08)
B	d6kv2b1	All beta proteins	beta-Trefoil	STI-like	automated matches	automated matches	(Senna obtusifolia ) [TaxId: 346985 ],	SCOPe (2.08)
B	d6kv2b2	Artifacts	Tags	Tags	Tags	N-terminal Tags	(Senna obtusifolia ) [TaxId: 346985 ],	SCOPe (2.08)
C [auth D]	d6kv2d1	All beta proteins	beta-Trefoil	STI-like	automated matches	automated matches	(Senna obtusifolia ) [TaxId: 346985 ],	SCOPe (2.08)
C [auth D]	d6kv2d2	Artifacts	Tags	Tags	Tags	N-terminal Tags	(Senna obtusifolia ) [TaxId: 346985 ],	SCOPe (2.08)
D [auth C]	d6kv2c1	All beta proteins	beta-Trefoil	STI-like	automated matches	automated matches	(Senna obtusifolia ) [TaxId: 346985 ],	SCOPe (2.08)
D [auth C]	d6kv2c2	Artifacts	Tags	Tags	Tags	N-terminal Tags	(Senna obtusifolia ) [TaxId: 346985 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2B Superfamily	STI-like	8096120	3000715	SCOP2B (2022-06-29)
B	SCOP2 Family	Kunitz (STI) inhibitors	8096119	4002025	SCOP2 (2022-06-29)
B	SCOP2 Superfamily	STI-like	8096120	3000715	SCOP2 (2022-06-29)
C [auth D]	SCOP2B Superfamily	STI-like	8096120	3000715	SCOP2B (2022-06-29)
D [auth C]	SCOP2B Superfamily	STI-like	8096120	3000715	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	PF00197	e6kv2A1	A: beta duplicates or obligate multimers	X: beta-Trefoil (From Topology)	H: beta-Trefoil (From Topology)	T: beta-Trefoil	F: PF00197	ECOD (1.6)
B	PF00197	e6kv2B1	A: beta duplicates or obligate multimers	X: beta-Trefoil (From Topology)	H: beta-Trefoil (From Topology)	T: beta-Trefoil	F: PF00197	ECOD (1.6)
C [auth D]	PF00197	e6kv2D1	A: beta duplicates or obligate multimers	X: beta-Trefoil (From Topology)	H: beta-Trefoil (From Topology)	T: beta-Trefoil	F: PF00197	ECOD (1.6)
D [auth C]	PF00197	e6kv2C1	A: beta duplicates or obligate multimers	X: beta-Trefoil (From Topology)	H: beta-Trefoil (From Topology)	T: beta-Trefoil	F: PF00197	ECOD (1.6)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B, C [auth D], D [auth C]	PF00197	Trypsin and protease inhibitor (Kunitz_legume)	Trypsin and protease inhibitor	-	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B, C [auth D], D [auth C]	Trypsin inhibitor 1	enzyme regulator activity molecular function inhibitor activity peptidase regulator activity serine-type endopeptidase inhibitor activity molecular function regulator activity enzyme inhibitor activity peptidase inhibitor activity endopeptidase regulator activity endopeptidase inhibitor activity oxidoreductase activity oxalate oxidase activity oxidoreductase activity, acting on the aldehyde or oxo group of donors catalytic activity oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor	-	-

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B, C [auth D], D [auth C]	IPR002160	Proteinase inhibitor I3, Kunitz legume	Family
A, B, C [auth D], D [auth C]	IPR011065	Kunitz inhibitor STI-like superfamily	Homologous Superfamily

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.