Annotations: 6KHP

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A	d6khpa_	Alpha and beta proteins (a/b)	PLP-dependent transferase-like	PLP-dependent transferases	automated matches	automated matches	Rice (Oryza sativa Japonica Group ) [TaxId: 39947 ],	SCOPe (2.08)
B	d6khpb_	Alpha and beta proteins (a/b)	PLP-dependent transferase-like	PLP-dependent transferases	automated matches	automated matches	Rice (Oryza sativa Japonica Group ) [TaxId: 39947 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2 Family	Pyridoxal-dependent decarboxylase	8099859	4003328	SCOP2 (2022-06-29)
A	SCOP2 Superfamily	PLP-dependent transferases	8099860	3000954	SCOP2 (2022-06-29)
B	SCOP2B Superfamily	PLP-dependent transferases	8099860	3000954	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	PF00282	e6khpA2	A: a+b two layers	X: C-terminal domain in some PLP-dependent transferases (From Topology)	H: C-terminal domain in some PLP-dependent transferases (From Topology)	T: C-terminal domain in some PLP-dependent transferases	F: PF00282	ECOD (1.6)
A	PF00282	e6khpA1	A: a/b three-layered sandwiches	X: PLP-dependent transferases (From Topology)	H: PLP-dependent transferases (From Topology)	T: PLP-dependent transferases	F: PF00282	ECOD (1.6)
B	PF00282	e6khpB1	A: a+b two layers	X: C-terminal domain in some PLP-dependent transferases (From Topology)	H: C-terminal domain in some PLP-dependent transferases (From Topology)	T: C-terminal domain in some PLP-dependent transferases	F: PF00282	ECOD (1.6)
B	PF00282	e6khpB2	A: a/b three-layered sandwiches	X: PLP-dependent transferases (From Topology)	H: PLP-dependent transferases (From Topology)	T: PLP-dependent transferases	F: PF00282	ECOD (1.6)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B	PF00282	Pyridoxal-dependent decarboxylase conserved domain (Pyridoxal_deC)	Pyridoxal-dependent decarboxylase conserved domain	-	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B	Tryptophan decarboxylase 1	aromatic-L-amino-acid decarboxylase activity 5-hydroxy-L-tryptophan decarboxylase activity carboxy-lyase activity lyase activity catalytic activity carbon-carbon lyase activity vitamin binding vitamin B6 binding pyridoxal phosphate binding ion binding binding organic cyclic compound binding anion binding heterocyclic compound binding aromatic-L-amino-acid decarboxylase activity 5-hydroxy-L-tryptophan decarboxylase activity carboxy-lyase activity lyase activity catalytic activity carbon-carbon lyase activity vitamin binding vitamin B6 binding pyridoxal phosphate binding ion binding binding organic cyclic compound binding anion binding heterocyclic compound binding small molecule binding L-tryptophan decarboxylase activity	serotonin metabolic process oxoacid metabolic process organic hydroxy compound metabolic process organonitrogen compound biosynthetic process indole-containing compound metabolic process amino acid metabolic process organic acid metabolic process primary amino compound metabolic process alpha-amino acid metabolic process ammonium ion metabolic process organic substance metabolic process indole-containing compound biosynthetic process organic substance biosynthetic process indolalkylamine metabolic process serotonin metabolic process oxoacid metabolic process organic hydroxy compound metabolic process organonitrogen compound biosynthetic process indole-containing compound metabolic process amino acid metabolic process organic acid metabolic process primary amino compound metabolic process alpha-amino acid metabolic process ammonium ion metabolic process organic substance metabolic process indole-containing compound biosynthetic process organic substance biosynthetic process indolalkylamine metabolic process small molecule metabolic process serotonin biosynthetic process serotonin biosynthetic process from tryptophan organonitrogen compound metabolic process aromatic amino acid metabolic process cellular metabolic process carboxylic acid metabolic process primary amino compound biosynthetic process primary metabolic process tryptophan metabolic process organic cyclic compound metabolic process amine metabolic process biosynthetic process phenol-containing compound metabolic process organic hydroxy compound biosynthetic process organic cyclic compound biosynthetic process phenol-containing compound biosynthetic process metabolic process cellular process biogenic amine metabolic process	intracellular anatomical structure cytoplasm cellular anatomical entity

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B	IPR015424	Pyridoxal phosphate-dependent transferase	Homologous Superfamily
A, B	IPR015421	Pyridoxal phosphate-dependent transferase, major domain	Homologous Superfamily
A, B	IPR010977	Aromatic-L-amino-acid decarboxylase	Family
A, B	IPR015422	Pyridoxal phosphate-dependent transferase, small domain	Homologous Superfamily
A, B	IPR002129	Pyridoxal phosphate-dependent decarboxylase	Family
A, B	IPR021115	Pyridoxal-phosphate binding site	Binding Site

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.