6KD5

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	PF15494	e6kd5A1	A: a+b complex topology	X: SRCR-like	H: SRCR-like (From Topology)	T: SRCR-like	F: PF15494	ECOD (1.6)
A	PF00057	e6kd5A2	A: few secondary structure elements	X: EGF-like	H: LDL receptor-like module (From Topology)	T: LDL receptor-like module	F: PF00057	ECOD (1.6)
B	PF00089	e6kd5B1	A: beta barrels	X: cradle loop barrel	H: RIFT-related	T: FMN-binding split barrel 2	F: PF00089	ECOD (1.6)

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
B	2.40.10.10	Mainly Beta	Beta Barrel	Thrombin, subunit H	Trypsin-like serine proteases	CATH (utative)

Chains	Accession	Name	Description	Comments	Source
A	PF15494	Scavenger receptor cysteine-rich domain (SRCR_2)	Scavenger receptor cysteine-rich domain	SRCR_2 is a scavenger receptor cysteine-rich domain family found largely on vertebrate sequences up-stream of the trypsin-like transmembrane serine protease, Spinesin.	Domain
B	PF00089	Trypsin (Trypsin)	Trypsin	-	Domain

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A	Transmembrane protease serine 13	peptidase activity catalytic activity, acting on a protein serine hydrolase activity serine-type peptidase activity hydrolase activity serine-type endopeptidase activity catalytic activity endopeptidase activity	organic substance metabolic process organonitrogen compound metabolic process proteolysis metabolic process primary metabolic process protein metabolic process macromolecule metabolic process	extracellular region extracellular space cellular anatomical entity blood microparticle membrane cell periphery plasma membrane intracellular anatomical structure cytoplasm
B	Transmembrane protease serine 13	peptidase activity catalytic activity, acting on a protein serine hydrolase activity serine-type peptidase activity hydrolase activity serine-type endopeptidase activity catalytic activity endopeptidase activity	organic substance metabolic process organonitrogen compound metabolic process proteolysis metabolic process primary metabolic process protein metabolic process macromolecule metabolic process	extracellular region extracellular space cellular anatomical entity blood microparticle membrane cell periphery plasma membrane intracellular anatomical structure cytoplasm
C	DECANOYL-ARG-VAL-LYS-ARG-CHLOROMETHYLKETONE INHIBITOR	-	-	-

Chains	Accession	Name	Type
A	IPR017448	SRCR-like domain	Domain
A	IPR002172	Low-density lipoprotein (LDL) receptor class A repeat	Repeat
A	IPR009003	Peptidase S1, PA clan	Homologous Superfamily
A	IPR001190	SRCR domain	Domain
A	IPR001314	Peptidase S1A, chymotrypsin family	Family
A	IPR033116	Serine proteases, trypsin family, serine active site	Active Site
A	IPR036772	SRCR-like domain superfamily	Homologous Superfamily
A	IPR001254	Serine proteases, trypsin domain	Domain
A	IPR017327	Peptidase S1A, TMPRSS13	Family
A	IPR043504	Peptidase S1, PA clan, chymotrypsin-like fold	Homologous Superfamily
A	IPR018114	Serine proteases, trypsin family, histidine active site	Active Site
B	IPR017448	SRCR-like domain	Domain
B	IPR002172	Low-density lipoprotein (LDL) receptor class A repeat	Repeat
B	IPR009003	Peptidase S1, PA clan	Homologous Superfamily
B	IPR001190	SRCR domain	Domain
B	IPR001314	Peptidase S1A, chymotrypsin family	Family
B	IPR033116	Serine proteases, trypsin family, serine active site	Active Site
B	IPR036772	SRCR-like domain superfamily	Homologous Superfamily
B	IPR001254	Serine proteases, trypsin domain	Domain
B	IPR017327	Peptidase S1A, TMPRSS13	Family
B	IPR043504	Peptidase S1, PA clan, chymotrypsin-like fold	Homologous Superfamily
B	IPR018114	Serine proteases, trypsin family, histidine active site	Active Site