Annotations: 6K0A

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2 Family	Rpp14/Pop5-like	8095394	4001975	SCOP2 (2022-06-29)
A	SCOP2 Superfamily	Rnp2-like	8095395	3000630	SCOP2 (2022-06-29)
G [auth B]	SCOP2B Superfamily	Rnp2-like	8095395	3000630	SCOP2B (2022-06-29)
C [auth E]	SCOP2 Family	RNase P subunit p29-like	8095072	4000863	SCOP2 (2022-06-29)
C [auth E]	SCOP2 Superfamily	Rof/RNase P subunit-like	8095073	3001815	SCOP2 (2022-06-29)
I [auth F]	SCOP2B Superfamily	Rof/RNase P subunit-like	8095073	3001815	SCOP2B (2022-06-29)
E [auth I]	SCOP2B Superfamily	L30e-like	8033665	3001739	SCOP2B (2022-06-29)
K [auth J]	SCOP2B Superfamily	L30e-like	8033665	3001739	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	PF01900	e6k0aA1	A: a+b two layers	X: Alpha-beta plaits	H: Rpp14/Pop5-like (From Topology)	T: Rpp14/Pop5-like	F: PF01900	ECOD (1.6)
G [auth B]	PF01900	e6k0aB1	A: a+b two layers	X: Alpha-beta plaits	H: Rpp14/Pop5-like (From Topology)	T: Rpp14/Pop5-like	F: PF01900	ECOD (1.6)
B [auth C]	PF01876	e6k0aC1	A: a/b barrels	X: TIM beta/alpha-barrel	H: TIM barrels (From Topology)	T: TIM barrels	F: PF01876	ECOD (1.6)
H [auth D]	PF01876	e6k0aD1	A: a/b barrels	X: TIM beta/alpha-barrel	H: TIM barrels (From Topology)	T: TIM barrels	F: PF01876	ECOD (1.6)
C [auth E]	PF01868	e6k0aE1	A: beta barrels	X: SH3	H: RNase P subunit p29 (From Topology)	T: RNase P subunit p29	F: PF01868	ECOD (1.6)
I [auth F]	PF01868	e6k0aF1	A: beta barrels	X: SH3	H: RNase P subunit p29 (From Topology)	T: RNase P subunit p29	F: PF01868	ECOD (1.6)
D [auth G]	PF04032	e6k0aG1	A: few secondary structure elements	X: Rubredoxin-like	H: Rubredoxin-related	T: Rubredoxin-related	F: PF04032	ECOD (1.6)
J [auth H]	PF04032	e6k0aH1	A: few secondary structure elements	X: Rubredoxin-like	H: Rubredoxin-related	T: Rubredoxin-related	F: PF04032	ECOD (1.6)
E [auth I]	PF01248	e6k0aI1	A: a+b three layers	X: Bacillus chorismate mutase-like	H: L30e-like (From Topology)	T: L30e-like	F: PF01248	ECOD (1.6)
K [auth J]	PF01248	e6k0aJ1	A: a+b three layers	X: Bacillus chorismate mutase-like	H: L30e-like (From Topology)	T: L30e-like	F: PF01248	ECOD (1.6)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, G [auth B]	PF01900	Rpp14/Pop5 family (RNase_P_Rpp14)	Rpp14/Pop5 family	-	Family
B [auth C], H [auth D]	PF01876	RNase P subunit p30 (RNase_P_p30)	RNase P subunit p30	This protein is part of the RNase P complex that is involved in tRNA maturation [1].	Domain
C [auth E], I [auth F]	PF01868	Ribonuclease P/MRP, subunit p29 (RNase_P-MRP_p29)	Ribonuclease P/MRP, subunit p29	-	Family
D [auth G], J [auth H]	PF04032	RNAse P Rpr2/Rpp21/SNM1 subunit domain (Rpr2)	RNAse P Rpr2/Rpp21/SNM1 subunit domain	-	Family
E [auth I], K [auth J]	PF01248	Ribosomal protein L7Ae/L30e/S12e/Gadd45 family (Ribosomal_L7Ae)	Ribosomal protein L7Ae/L30e/S12e/Gadd45 family	This family includes: Ribosomal L7A from metazoa, Ribosomal L8-A and L8-B from fungi, 30S ribosomal protein HS6 from archaebacteria, 40S ribosomal protein S12 from eukaryotes, Ribosomal protein L30 from eukaryotes and archaebacteria. Gadd45 and MyD11 ...	This family includes: Ribosomal L7A from metazoa, Ribosomal L8-A and L8-B from fungi, 30S ribosomal protein HS6 from archaebacteria, 40S ribosomal protein S12 from eukaryotes, Ribosomal protein L30 from eukaryotes and archaebacteria. Gadd45 and MyD118 [1].	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, G [auth B]	Ribonuclease P protein component 2	tRNA-specific ribonuclease activity endonuclease activity RNA endonuclease activity, producing 5'-phosphomonoesters catalytic activity, acting on RNA catalytic activity, acting on a nucleic acid RNA nuclease activity hydrolase activity catalytic activity, acting on a tRNA nuclease activity hydrolase activity, acting on ester bonds RNA endonuclease activity ribonuclease P activity endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters catalytic activity	cellular biosynthetic process cellular metabolic process RNA metabolic process primary metabolic process gene expression macromolecule biosynthetic process nucleic acid metabolic process tRNA metabolic process nucleobase-containing compound metabolic process organic cyclic compound metabolic process organic substance metabolic process biosynthetic process tRNA processing organic substance biosynthetic process nucleic acid catabolic process cellular biosynthetic process cellular metabolic process RNA metabolic process primary metabolic process gene expression macromolecule biosynthetic process nucleic acid metabolic process tRNA metabolic process nucleobase-containing compound metabolic process organic cyclic compound metabolic process organic substance metabolic process biosynthetic process tRNA processing organic substance biosynthetic process nucleic acid catabolic process RNA 5'-end processing metabolic process cellular process macromolecule metabolic process RNA processing tRNA 5'-leader removal tRNA 5'-end processing	intracellular anatomical structure cytoplasm cellular anatomical entity protein-containing complex endoribonuclease complex catalytic complex ribonuclease P complex ribonucleoprotein complex intracellular protein-containing complex endonuclease complex
B [auth C], H [auth D]	Ribonuclease P protein component 3	tRNA-specific ribonuclease activity endonuclease activity RNA endonuclease activity, producing 5'-phosphomonoesters catalytic activity, acting on RNA catalytic activity, acting on a nucleic acid RNA nuclease activity hydrolase activity catalytic activity, acting on a tRNA nuclease activity hydrolase activity, acting on ester bonds RNA endonuclease activity ribonuclease P activity endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters catalytic activity	cellular biosynthetic process cellular metabolic process RNA metabolic process primary metabolic process gene expression macromolecule biosynthetic process nucleic acid metabolic process tRNA metabolic process nucleobase-containing compound metabolic process organic cyclic compound metabolic process organic substance metabolic process biosynthetic process tRNA processing organic substance biosynthetic process nucleic acid catabolic process cellular biosynthetic process cellular metabolic process RNA metabolic process primary metabolic process gene expression macromolecule biosynthetic process nucleic acid metabolic process tRNA metabolic process nucleobase-containing compound metabolic process organic cyclic compound metabolic process organic substance metabolic process biosynthetic process tRNA processing organic substance biosynthetic process nucleic acid catabolic process RNA 5'-end processing metabolic process cellular process macromolecule metabolic process RNA processing tRNA 5'-leader removal tRNA 5'-end processing	intracellular anatomical structure cytoplasm cellular anatomical entity protein-containing complex endoribonuclease complex catalytic complex ribonuclease P complex ribonucleoprotein complex intracellular protein-containing complex endonuclease complex
C [auth E], I [auth F]	Ribonuclease P protein component 1	tRNA-specific ribonuclease activity endonuclease activity RNA endonuclease activity, producing 5'-phosphomonoesters catalytic activity, acting on RNA catalytic activity, acting on a nucleic acid RNA nuclease activity hydrolase activity catalytic activity, acting on a tRNA nuclease activity hydrolase activity, acting on ester bonds RNA endonuclease activity ribonuclease P activity endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters catalytic activity tRNA-specific ribonuclease activity endonuclease activity RNA endonuclease activity, producing 5'-phosphomonoesters catalytic activity, acting on RNA catalytic activity, acting on a nucleic acid RNA nuclease activity hydrolase activity catalytic activity, acting on a tRNA nuclease activity hydrolase activity, acting on ester bonds RNA endonuclease activity ribonuclease P activity endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters catalytic activity RNA binding binding organic cyclic compound binding nucleic acid binding ribonuclease P RNA binding	cellular biosynthetic process cellular metabolic process RNA metabolic process primary metabolic process gene expression macromolecule biosynthetic process nucleic acid metabolic process tRNA metabolic process nucleobase-containing compound metabolic process organic cyclic compound metabolic process organic substance metabolic process biosynthetic process tRNA processing organic substance biosynthetic process nucleic acid catabolic process cellular biosynthetic process cellular metabolic process RNA metabolic process primary metabolic process gene expression macromolecule biosynthetic process nucleic acid metabolic process tRNA metabolic process nucleobase-containing compound metabolic process organic cyclic compound metabolic process organic substance metabolic process biosynthetic process tRNA processing organic substance biosynthetic process nucleic acid catabolic process RNA 5'-end processing metabolic process cellular process macromolecule metabolic process RNA processing tRNA 5'-leader removal tRNA 5'-end processing	protein-containing complex endoribonuclease complex catalytic complex sno(s)RNA-containing ribonucleoprotein complex ribonuclease MRP complex ribonucleoprotein complex intracellular protein-containing complex endonuclease complex intracellular anatomical structure cytoplasm cellular anatomical entity ribonuclease P complex
D [auth G], J [auth H]	Ribonuclease P protein component 4	tRNA-specific ribonuclease activity endonuclease activity RNA endonuclease activity, producing 5'-phosphomonoesters catalytic activity, acting on RNA catalytic activity, acting on a nucleic acid RNA nuclease activity hydrolase activity catalytic activity, acting on a tRNA nuclease activity hydrolase activity, acting on ester bonds RNA endonuclease activity ribonuclease P activity endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters catalytic activity tRNA-specific ribonuclease activity endonuclease activity RNA endonuclease activity, producing 5'-phosphomonoesters catalytic activity, acting on RNA catalytic activity, acting on a nucleic acid RNA nuclease activity hydrolase activity catalytic activity, acting on a tRNA nuclease activity hydrolase activity, acting on ester bonds RNA endonuclease activity ribonuclease P activity endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters catalytic activity cation binding transition metal ion binding zinc ion binding ion binding binding metal ion binding small molecule binding	cellular biosynthetic process cellular metabolic process RNA metabolic process primary metabolic process gene expression macromolecule biosynthetic process nucleic acid metabolic process tRNA metabolic process nucleobase-containing compound metabolic process organic cyclic compound metabolic process organic substance metabolic process biosynthetic process tRNA processing organic substance biosynthetic process nucleic acid catabolic process cellular biosynthetic process cellular metabolic process RNA metabolic process primary metabolic process gene expression macromolecule biosynthetic process nucleic acid metabolic process tRNA metabolic process nucleobase-containing compound metabolic process organic cyclic compound metabolic process organic substance metabolic process biosynthetic process tRNA processing organic substance biosynthetic process nucleic acid catabolic process RNA 5'-end processing metabolic process cellular process macromolecule metabolic process RNA processing tRNA 5'-leader removal tRNA 5'-end processing	intracellular anatomical structure cytoplasm cellular anatomical entity protein-containing complex endoribonuclease complex catalytic complex ribonuclease P complex ribonucleoprotein complex intracellular protein-containing complex endonuclease complex
E [auth I], K [auth J]	50S ribosomal protein L7Ae	RNA binding binding organic cyclic compound binding rRNA binding nucleic acid binding box C/D sno(s)RNA binding snoRNA binding tRNA-specific ribonuclease activity endonuclease activity RNA endonuclease activity, producing 5'-phosphomonoesters catalytic activity, acting on RNA catalytic activity, acting on a nucleic acid RNA nuclease activity hydrolase activity RNA binding binding organic cyclic compound binding rRNA binding nucleic acid binding box C/D sno(s)RNA binding snoRNA binding tRNA-specific ribonuclease activity endonuclease activity RNA endonuclease activity, producing 5'-phosphomonoesters catalytic activity, acting on RNA catalytic activity, acting on a nucleic acid RNA nuclease activity hydrolase activity catalytic activity, acting on a tRNA nuclease activity hydrolase activity, acting on ester bonds RNA endonuclease activity ribonuclease P activity endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters catalytic activity structural molecule activity structural constituent of ribosome	cellular biosynthetic process cellular metabolic process RNA metabolic process primary metabolic process gene expression macromolecule biosynthetic process nucleic acid metabolic process tRNA metabolic process nucleobase-containing compound metabolic process organic cyclic compound metabolic process organic substance metabolic process biosynthetic process tRNA processing organic substance biosynthetic process nucleic acid catabolic process cellular biosynthetic process cellular metabolic process RNA metabolic process primary metabolic process gene expression macromolecule biosynthetic process nucleic acid metabolic process tRNA metabolic process nucleobase-containing compound metabolic process organic cyclic compound metabolic process organic substance metabolic process biosynthetic process tRNA processing organic substance biosynthetic process nucleic acid catabolic process RNA 5'-end processing metabolic process cellular process macromolecule metabolic process RNA processing tRNA 5'-leader removal tRNA 5'-end processing ribonucleoprotein complex biogenesis protein-containing complex organization small nucleolar ribonucleoprotein complex assembly protein-RNA complex assembly cellular component organization cellular component biogenesis protein-RNA complex organization cellular component assembly protein-containing complex assembly cellular component organization or biogenesis box C/D snoRNP assembly ribosome biogenesis organonitrogen compound metabolic process organonitrogen compound biosynthetic process translation protein metabolic process	intracellular anatomical structure cytoplasm cellular anatomical entity intracellular organelle organelle intracellular non-membrane-bounded organelle ribosome non-membrane-bounded organelle box C/D methylation guide snoRNP complex protein-containing complex sno(s)RNA-containing ribonucleoprotein complex ribonucleoprotein complex box C/D RNP complex
F [auth X], L [auth Y]	RPR	-	-	-

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, G [auth B]	IPR002759	RNase P subunit Pop5/Rpp14/Rnp2-like	Family
A, G [auth B]	IPR016434	Ribonuclease P protein subunit Rnp2, archaea	Family
A, G [auth B]	IPR038085	RNase P subunit Pop5/Rpp14/Rnp2-like domain superfamily	Homologous Superfamily
B [auth C], H [auth D]	IPR016195	Polymerase/histidinol phosphatase-like	Homologous Superfamily
B [auth C], H [auth D]	IPR023539	Ribonuclease P, protein component 3, archaeal	Family
B [auth C], H [auth D]	IPR002738	RNase P subunit p30	Family
C [auth E], I [auth F]	IPR023538	Ribonuclease P protein subunit RNP1	Family
C [auth E], I [auth F]	IPR036980	Ribonuclease P/MRP subunit Rpp29 superfamily	Homologous Superfamily
C [auth E], I [auth F]	IPR002730	Ribonuclease P protein subunit Rpp29/RNP1	Family
C [auth E], I [auth F]	IPR023534	Rof/RNase P-like	Homologous Superfamily
C [auth E], I [auth F]	IPR016848	Ribonuclease P/MRP subunit Rpp29	Family
D [auth G], J [auth H]	IPR007175	Ribonuclease P subunit, Rpr2/Snm1/Rpp21	Family
D [auth G], J [auth H]	IPR016432	Ribonuclease P subunit RNP4	Family
E [auth I], K [auth J]	IPR004038	Ribosomal protein eL8/eL30/eS12/Gadd45	Domain
E [auth I], K [auth J]	IPR022481	Large ribosomal subunit protein eL8, archaea	Family
E [auth I], K [auth J]	IPR004037	Large ribosomal subunit protein eL8-like, conserved site	Conserved Site
E [auth I], K [auth J]	IPR029064	Ribosomal protein eL30-like superfamily	Homologous Superfamily
E [auth I], K [auth J]	IPR018492	Ribosomal protein eL8/Nhp2 family	Family

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.