6JP9
Crsytal structure of a XMP complexed ATPPase subunit of M. jannaschii GMP synthetase
Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage
Domain Annotation: ECOD Classification ECOD Database Homepage
Chains | Family Name | Domain Identifier | Architecture | Possible Homology | Homology | Topology | Family | Provenance Source (Version) |
---|---|---|---|---|---|---|---|---|
A | PF00958 | e6jp9A2 | A: a+b two layers | X: Alpha-lytic protease prodomain-like | H: GMP synthetase C-terminal dimerisation domain (From Topology) | T: GMP synthetase C-terminal dimerisation domain | F: PF00958 | ECOD (1.6) |
A | PF02540 | e6jp9A1 | A: a/b three-layered sandwiches | X: HUP domain-like | H: HUP domains (From Topology) | T: HUP domains | F: PF02540 | ECOD (1.6) |
B | PF00958 | e6jp9B1 | A: a+b two layers | X: Alpha-lytic protease prodomain-like | H: GMP synthetase C-terminal dimerisation domain (From Topology) | T: GMP synthetase C-terminal dimerisation domain | F: PF00958 | ECOD (1.6) |
B | PF02540 | e6jp9B2 | A: a/b three-layered sandwiches | X: HUP domain-like | H: HUP domains (From Topology) | T: HUP domains | F: PF02540 | ECOD (1.6) |
C | PF00958 | e6jp9C1 | A: a+b two layers | X: Alpha-lytic protease prodomain-like | H: GMP synthetase C-terminal dimerisation domain (From Topology) | T: GMP synthetase C-terminal dimerisation domain | F: PF00958 | ECOD (1.6) |
C | PF02540 | e6jp9C2 | A: a/b three-layered sandwiches | X: HUP domain-like | H: HUP domains (From Topology) | T: HUP domains | F: PF02540 | ECOD (1.6) |
D | PF00958 | e6jp9D1 | A: a+b two layers | X: Alpha-lytic protease prodomain-like | H: GMP synthetase C-terminal dimerisation domain (From Topology) | T: GMP synthetase C-terminal dimerisation domain | F: PF00958 | ECOD (1.6) |
D | PF02540 | e6jp9D2 | A: a/b three-layered sandwiches | X: HUP domain-like | H: HUP domains (From Topology) | T: HUP domains | F: PF02540 | ECOD (1.6) |
Domain Annotation: CATH CATH Database Homepage
Chain | Domain | Class | Architecture | Topology | Homology | Provenance Source (Version) |
---|---|---|---|---|---|---|
A | 3.40.50.620 | Alpha Beta | 3-Layer(aba) Sandwich | Rossmann fold | HUPs | CATH (utative) |
A | 3.30.300.10 | Alpha Beta | 2-Layer Sandwich | GMP Synthetase | Chain A, domain 3 | CATH (utative) |
B | 3.40.50.620 | Alpha Beta | 3-Layer(aba) Sandwich | Rossmann fold | HUPs | CATH (utative) |
B | 3.30.300.10 | Alpha Beta | 2-Layer Sandwich | GMP Synthetase | Chain A, domain 3 | CATH (utative) |
C | 3.40.50.620 | Alpha Beta | 3-Layer(aba) Sandwich | Rossmann fold | HUPs | CATH (utative) |
C | 3.30.300.10 | Alpha Beta | 2-Layer Sandwich | GMP Synthetase | Chain A, domain 3 | CATH (utative) |
D | 3.40.50.620 | Alpha Beta | 3-Layer(aba) Sandwich | Rossmann fold | HUPs | CATH (utative) |
D | 3.30.300.10 | Alpha Beta | 2-Layer Sandwich | GMP Synthetase | Chain A, domain 3 | CATH (utative) |
Protein Family Annotation Pfam Database Homepage
Chains | Accession | Name | Description | Comments | Source |
---|---|---|---|---|---|
PF00958 | GMP synthase C terminal domain (GMP_synt_C) | GMP synthase C terminal domain | GMP synthetase is a glutamine amidotransferase from the de novo purine biosynthetic pathway. This family is the C-terminal domain specific to the GMP synthases Swiss:P49915 EC:6.3.5.2. In prokaryotes this domain mediates dimerisation. Eukaryotic GMP ... | Domain | |
PF02540 | NAD synthase (NAD_synthase) | NAD synthase | NAD synthase (EC:6.3.5.1) is involved in the de novo synthesis of NAD and is induced by stress factors such as heat shock and glucose limitation. | Domain |
Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage
InterPro: Protein Family Classification InterPro Database Homepage
Chains | Accession | Name | Type |
---|---|---|---|
IPR022310 | NAD/GMP synthase | Domain | |
IPR001674 | GMP synthase, C-terminal | Domain | |
IPR026598 | GMP synthase subunit B | Family | |
IPR025777 | GMP synthetase ATP pyrophosphatase domain | Domain | |
IPR014729 | Rossmann-like alpha/beta/alpha sandwich fold | Homologous Superfamily |