Annotations: 6JJL

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2B Superfamily	PDZ domain-like	8040752	3000388	SCOP2B (2022-06-29)
A	SCOP2B Superfamily	Trypsin-like serine proteases	8040753	3000114	SCOP2B (2022-06-29)
B	SCOP2B Superfamily	PDZ domain-like	8040752	3000388	SCOP2B (2022-06-29)
B	SCOP2B Superfamily	Trypsin-like serine proteases	8040753	3000114	SCOP2B (2022-06-29)
C	SCOP2B Superfamily	Trypsin-like serine proteases	8040753	3000114	SCOP2B (2022-06-29)
C	SCOP2B Superfamily	PDZ domain-like	8040752	3000388	SCOP2B (2022-06-29)
D	SCOP2B Superfamily	PDZ domain-like	8040752	3000388	SCOP2B (2022-06-29)
D	SCOP2B Superfamily	Trypsin-like serine proteases	8040753	3000114	SCOP2B (2022-06-29)
E	SCOP2B Superfamily	PDZ domain-like	8040752	3000388	SCOP2B (2022-06-29)
E	SCOP2B Superfamily	Trypsin-like serine proteases	8040753	3000114	SCOP2B (2022-06-29)
F	SCOP2B Superfamily	Trypsin-like serine proteases	8040753	3000114	SCOP2B (2022-06-29)
F	SCOP2B Superfamily	PDZ domain-like	8040752	3000388	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	PF13365	e6jjlA1	A: beta barrels	X: cradle loop barrel	H: RIFT-related	T: FMN-binding split barrel	F: PF13365	ECOD (1.6)
A	PF00595	e6jjlA2	A: beta barrels	X: PDZ domain (From Topology)	H: PDZ domain (From Topology)	T: PDZ domain	F: PF00595	ECOD (1.6)
B	PF13365	e6jjlB2	A: beta barrels	X: cradle loop barrel	H: RIFT-related	T: FMN-binding split barrel	F: PF13365	ECOD (1.6)
B	PF00595	e6jjlB3	A: beta barrels	X: PDZ domain (From Topology)	H: PDZ domain (From Topology)	T: PDZ domain	F: PF00595	ECOD (1.6)
C	PF13365	e6jjlC3	A: beta barrels	X: cradle loop barrel	H: RIFT-related	T: FMN-binding split barrel	F: PF13365	ECOD (1.6)
C	PF00595	e6jjlC2	A: beta barrels	X: PDZ domain (From Topology)	H: PDZ domain (From Topology)	T: PDZ domain	F: PF00595	ECOD (1.6)
D	PF13365	e6jjlD1	A: beta barrels	X: cradle loop barrel	H: RIFT-related	T: FMN-binding split barrel	F: PF13365	ECOD (1.6)
D	PF00595	e6jjlD3	A: beta barrels	X: PDZ domain (From Topology)	H: PDZ domain (From Topology)	T: PDZ domain	F: PF00595	ECOD (1.6)
E	PF13365	e6jjlE2	A: beta barrels	X: cradle loop barrel	H: RIFT-related	T: FMN-binding split barrel	F: PF13365	ECOD (1.6)
E	PF00595	e6jjlE1	A: beta barrels	X: PDZ domain (From Topology)	H: PDZ domain (From Topology)	T: PDZ domain	F: PF00595	ECOD (1.6)
F	PF13365	e6jjlF1	A: beta barrels	X: cradle loop barrel	H: RIFT-related	T: FMN-binding split barrel	F: PF13365	ECOD (1.6)
F	PF00595	e6jjlF3	A: beta barrels	X: PDZ domain (From Topology)	H: PDZ domain (From Topology)	T: PDZ domain	F: PF00595	ECOD (1.6)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B, C, D, E A, B, C, D, E, F	PF13365	Trypsin-like peptidase domain (Trypsin_2)	Trypsin-like peptidase domain	This family includes trypsin-like peptidase domains.	Domain
A, B, C, D, E A, B, C, D, E, F	PF00595	PDZ domain (PDZ)	PDZ domain	PDZ domains are found in diverse signaling proteins.	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B, C, D, E A, B, C, D, E, F	Periplasmic serine endoprotease DegP	peptidase activity catalytic activity, acting on a protein hydrolase activity catalytic activity serine hydrolase activity serine-type peptidase activity serine-type endopeptidase activity endopeptidase activity identical protein binding protein binding binding	organonitrogen compound metabolic process cellular biosynthetic process cellular metabolic process primary metabolic process gene expression macromolecule biosynthetic process protein maturation organic substance metabolic process protein folding biosynthetic process organic substance biosynthetic process metabolic process cellular process protein metabolic process organonitrogen compound metabolic process cellular biosynthetic process cellular metabolic process primary metabolic process gene expression macromolecule biosynthetic process protein maturation organic substance metabolic process protein folding biosynthetic process organic substance biosynthetic process metabolic process cellular process protein metabolic process macromolecule metabolic process chaperone-mediated protein folding response to oxidative stress response to stimulus response to stress proteolysis response to heat response to abiotic stimulus response to temperature stimulus organonitrogen compound catabolic process catabolic process proteolysis involved in protein catabolic process protein catabolic process macromolecule catabolic process protein quality control for misfolded or incompletely synthesized proteins organic substance catabolic process	cell periphery plasma membrane membrane cellular anatomical entity periplasmic space outer membrane-bounded periplasmic space cell envelope
G, H [auth M], I [auth H], J [auth N], K [auth I], G, H [auth M], I [auth H], J [auth N], K [auth I], L [auth Q], M [auth J], N [auth O], O [auth K], P [auth R], Q [auth L], R [auth P]	CYS-TYR-ARG-LYS-LEU	-	-	-

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B, C, D, E A, B, C, D, E, F	IPR009003	Peptidase S1, PA clan	Homologous Superfamily
A, B, C, D, E A, B, C, D, E, F	IPR001940	Peptidase S1C	Family
A, B, C, D, E A, B, C, D, E, F	IPR036034	PDZ superfamily	Homologous Superfamily
A, B, C, D, E A, B, C, D, E, F	IPR011782	Peptidase S1C, Do	Family
A, B, C, D, E A, B, C, D, E, F	IPR001478	PDZ domain	Domain

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.