Annotations: 6IFC

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
B	F_UNCLASSIFIED	e6ifcB1	A: beta barrels	X: cradle loop barrel	H: RIFT-related	T: AbrB	F: F_UNCLASSIFIED	ECOD (1.6)
F	F_UNCLASSIFIED	e6ifcF1	A: beta barrels	X: cradle loop barrel	H: RIFT-related	T: AbrB	F: F_UNCLASSIFIED	ECOD (1.6)
A	PF01850	e6ifcA1	A: a/b three-layered sandwiches	X: HAD domain-like	H: HAD domain-related	T: PIN domain-like	F: PF01850	ECOD (1.6)
C	PF01850	e6ifcC1	A: a/b three-layered sandwiches	X: HAD domain-like	H: HAD domain-related	T: PIN domain-like	F: PF01850	ECOD (1.6)
E	PF01850	e6ifcE1	A: a/b three-layered sandwiches	X: HAD domain-like	H: HAD domain-related	T: PIN domain-like	F: PF01850	ECOD (1.6)
G	PF01850	e6ifcG1	A: a/b three-layered sandwiches	X: HAD domain-like	H: HAD domain-related	T: PIN domain-like	F: PF01850	ECOD (1.6)
D	PF04014	e6ifcD1	A: beta barrels	X: cradle loop barrel	H: RIFT-related	T: AbrB	F: PF04014	ECOD (1.6)
H	F_UNCLASSIFIED	e6ifcH1	A: beta barrels	X: cradle loop barrel	H: RIFT-related	T: AbrB	F: F_UNCLASSIFIED	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	3.40.50.1010	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	5'-nuclease	CATH (utative)
C	3.40.50.1010	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	5'-nuclease	CATH (utative)
E	3.40.50.1010	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	5'-nuclease	CATH (utative)
G	3.40.50.1010	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	5'-nuclease	CATH (utative)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, C, E, G	PF01850	PIN domain (PIN)	PIN domain	-	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
B, F	Antitoxin VapB	DNA binding binding organic cyclic compound binding nucleic acid binding	-	-
A, C, E, G	tRNA(fMet)-specific endonuclease VapC	cation binding magnesium ion binding ion binding binding metal ion binding small molecule binding endonuclease activity nuclease activity hydrolase activity, acting on ester bonds hydrolase activity catalytic activity catalytic activity, acting on RNA catalytic activity, acting on a nucleic acid RNA nuclease activity	-	-
D, H	Antitoxin VapB	DNA binding binding organic cyclic compound binding nucleic acid binding	-	-

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
B, F	IPR047976	Antitoxin VapB2-like	Family
B, F	IPR037914	SpoVT-AbrB domain superfamily	Homologous Superfamily
B, F	IPR007159	SpoVT-AbrB domain	Domain
A, C, E, G	IPR002716	PIN domain	Domain
A, C, E, G	IPR029060	PIN-like domain superfamily	Homologous Superfamily
A, C, E, G	IPR022907	VapC family	Family
D, H	IPR047976	Antitoxin VapB2-like	Family
D, H	IPR037914	SpoVT-AbrB domain superfamily	Homologous Superfamily
D, H	IPR007159	SpoVT-AbrB domain	Domain

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.