6F5Z

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	PF08241	e6f5zA1	A: a/b three-layered sandwiches	X: Rossmann-like	H: Rossmann-related	T: S-adenosyl-L-methionine-dependent methyltransferases	F: PF08241	ECOD (1.6)
B	PF08241	e6f5zB1	A: a/b three-layered sandwiches	X: Rossmann-like	H: Rossmann-related	T: S-adenosyl-L-methionine-dependent methyltransferases	F: PF08241	ECOD (1.6)
C	PF03966	e6f5zC1	A: few secondary structure elements	X: Trm112p-like (From Topology)	H: Trm112p-like (From Topology)	T: Trm112p-like	F: PF03966	ECOD (1.6)
D	PF03966	e6f5zD1	A: few secondary structure elements	X: Trm112p-like (From Topology)	H: Trm112p-like (From Topology)	T: Trm112p-like	F: PF03966	ECOD (1.6)

Chains	Accession	Name	Description	Comments	Source
A, B	PF08241	Methyltransferase domain (Methyltransf_11)	Methyltransferase domain	Members of this family are SAM dependent methyltransferases.	Domain
C, D	PF03966	Trm112p-like protein (Trm112p)	Trm112p-like protein	The function of this family is uncertain. The bacterial members are about 60-70 amino acids in length and the eukaryotic examples are about 120 amino acids in length. The C terminus contains the strongest conservation. Trm112p is required for tRNA ...	The function of this family is uncertain. The bacterial members are about 60-70 amino acids in length and the eukaryotic examples are about 120 amino acids in length. The C terminus contains the strongest conservation. Trm112p is required for tRNA methylation in S. cerevisiae and is found in complexes with 2 tRNA methylases (TRM9 and TRM11) also with putative methyltransferase YDR140W [1]. The zinc-finger protein Ynr046w is plurifunctional and a component of the eRF1 methyltransferase in yeast [2]. The crystal structure of Ynr046w has been determined to 1.7 A resolution. It comprises a zinc-binding domain built from both the N- and C-terminal sequences and an inserted domain, absent from bacterial and archaeal orthologs of the protein, composed of three alpha-helices [2].	Domain

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B	24-sterol C-methyltransferase	transferase activity, transferring one-carbon groups transferase activity methyltransferase activity S-adenosylmethionine-dependent methyltransferase activity catalytic activity	methylation metabolic process biosynthetic process cellular biosynthetic process cellular metabolic process cellular process organic substance metabolic process organic substance biosynthetic process	-
C, D	UPF0434 family protein	transferase activity, transferring one-carbon groups transferase activity methyltransferase activity catalytic activity	methylation metabolic process	-

Chains	Accession	Name	Type
A, B	IPR029063	S-adenosyl-L-methionine-dependent methyltransferase superfamily	Homologous Superfamily
A, B	IPR013216	Methyltransferase type 11	Domain
C, D	IPR005651	Trm112-like	Family