6EWS

Solution Structure of Rhabdopeptide NRPS Docking Domain Kj12A-NDD

External Resource: Annotation


Domain Annotation: ECOD Classification ECOD Database Homepage

ChainsFamily NameDomain Identifier ArchitecturePossible HomologyHomologyTopologyFamilyProvenance Source (Version)
APF18563e6ewsA1 A: alpha duplicates or obligate multimersX: Docking domains in modular polyketide synthasesH: Class 3 N-terminal docking domain (From Topology)T: Class 3 N-terminal docking domainF: PF18563ECOD (1.6)

Protein Family Annotation Pfam Database Homepage

ChainsAccessionNameDescriptionCommentsSource
PF18563TubC N-terminal docking domain (TubC_N)TubC N-terminal docking domainThis is the N-terminal docking domain found in TubC proteins from the tubulysin polyketide synthase and nonribosomal polypeptide synthetase (PKS-NRPS) system, which binds to C-terminal docking domain of TubB [1].Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

ChainsPolymerMolecular FunctionBiological ProcessCellular Component
NRPS Kj12A-NDD - -

InterPro: Protein Family Classification InterPro Database Homepage

ChainsAccessionNameType
IPR044894TubC, N-terminal docking domain superfamilyHomologous Superfamily
IPR009081Phosphopantetheine binding ACP domainDomain
IPR020459AMP-bindingDomain
IPR010071Amino acid adenylation domainDomain
IPR020845AMP-binding, conserved siteConserved Site
IPR023213Chloramphenicol acetyltransferase-like domain superfamilyHomologous Superfamily
IPR045851AMP-binding enzyme, C-terminal domain superfamilyHomologous Superfamily
IPR020806Polyketide synthase, phosphopantetheine-binding domainDomain
IPR001242Condensation domainDomain
IPR036736ACP-like superfamilyHomologous Superfamily
IPR041464TubC, N-terminal docking domainDomain
IPR000873AMP-dependent synthetase/ligase domainDomain