6E31

Crystal structure of RIAM in an autoinhibited configuration.

External Resource: Annotation


Protein Family Annotation Pfam Database Homepage

ChainsAccessionNameDescriptionCommentsSource
PF00788Ras association (RalGDS/AF-6) domain (RA)Ras association (RalGDS/AF-6) domainRasGTP effectors (in cases of AF6, canoe and RalGDS); putative RasGTP effectors in other cases. Recent evidence (not yet in MEDLINE) shows that some RA domains do NOT bind RasGTP. Predicted structure [3] similar to that determined [1], and that of th ...RasGTP effectors (in cases of AF6, canoe and RalGDS); putative RasGTP effectors in other cases. Recent evidence (not yet in MEDLINE) shows that some RA domains do NOT bind RasGTP. Predicted structure [3] similar to that determined [1], and that of the RasGTP-binding domain of Raf kinase.
Domain
PF00169PH domain (PH)PH domainPH stands for pleckstrin homology.Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

ChainsPolymerMolecular FunctionBiological ProcessCellular Component
Rap1-interacting adapter molecule-

InterPro: Protein Family Classification InterPro Database Homepage

ChainsAccessionNameType
IPR001849Pleckstrin homology domainDomain
IPR000159Ras-associating domainDomain
IPR039664GRB/APBB1IPFamily
IPR011993PH-like domain superfamilyHomologous Superfamily
IPR039665APBB1IP, PH domainDomain
IPR029071Ubiquitin-like domain superfamilyHomologous Superfamily