6DWO

Crystal structure of alpha-1-2-mannosidase from Enterococcus faecalis V583

External Resource: Annotation

Domain Annotation: ECOD Classification
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	PF17678	e6dwoA3	A: beta sandwiches	X: Glycosyl hydrolase domain-like	H: supersandwich (From Topology)	T: supersandwich	F: PF17678	ECOD (1.6)
A	PF07971	e6dwoA2	A: beta sandwiches	X: Glycosyl hydrolase domain-like	H: Glycoside hydrolase family 127 middle domain-related (From Topology)	T: Glycoside hydrolase family 127 middle domain-related	F: PF07971	ECOD (1.6)
A	PF07971	e6dwoA1	A: alpha superhelices	X: Repetitive alpha hairpins	H: alpha/alpha toroid (From Topology)	T: alpha/alpha toroid	F: PF07971	ECOD (1.6)
B	PF17678	e6dwoB2	A: beta sandwiches	X: Glycosyl hydrolase domain-like	H: supersandwich (From Topology)	T: supersandwich	F: PF17678	ECOD (1.6)
B	PF07971	e6dwoB1	A: beta sandwiches	X: Glycosyl hydrolase domain-like	H: Glycoside hydrolase family 127 middle domain-related (From Topology)	T: Glycoside hydrolase family 127 middle domain-related	F: PF07971	ECOD (1.6)
B	PF07971	e6dwoB3	A: alpha superhelices	X: Repetitive alpha hairpins	H: alpha/alpha toroid (From Topology)	T: alpha/alpha toroid	F: PF07971	ECOD (1.6)
C	PF17678	e6dwoC1	A: beta sandwiches	X: Glycosyl hydrolase domain-like	H: supersandwich (From Topology)	T: supersandwich	F: PF17678	ECOD (1.6)
C	PF07971	e6dwoC2	A: beta sandwiches	X: Glycosyl hydrolase domain-like	H: Glycoside hydrolase family 127 middle domain-related (From Topology)	T: Glycoside hydrolase family 127 middle domain-related	F: PF07971	ECOD (1.6)
C	PF07971	e6dwoC3	A: alpha superhelices	X: Repetitive alpha hairpins	H: alpha/alpha toroid (From Topology)	T: alpha/alpha toroid	F: PF07971	ECOD (1.6)
D	PF17678	e6dwoD1	A: beta sandwiches	X: Glycosyl hydrolase domain-like	H: supersandwich (From Topology)	T: supersandwich	F: PF17678	ECOD (1.6)
D	PF07971	e6dwoD3	A: beta sandwiches	X: Glycosyl hydrolase domain-like	H: Glycoside hydrolase family 127 middle domain-related (From Topology)	T: Glycoside hydrolase family 127 middle domain-related	F: PF07971	ECOD (1.6)
D	PF07971	e6dwoD2	A: alpha superhelices	X: Repetitive alpha hairpins	H: alpha/alpha toroid (From Topology)	T: alpha/alpha toroid	F: PF07971	ECOD (1.6)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B, C, D	PF07971	Glycosyl hydrolase family 92 catalytic domain (Glyco_hydro_92)	Glycosyl hydrolase family 92 catalytic domain	-	Repeat
A, B, C, D	PF17678	Glycosyl hydrolase family 92 N-terminal domain (Glyco_hydro_92N)	Glycosyl hydrolase family 92 N-terminal domain	This domain is found at the N-terminus of family 92 glycosyl hydrolase proteins.	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B, C, D	Alpha-1,2-mannosidase	binding carbohydrate binding catalytic activity	carbohydrate metabolic process organic substance metabolic process primary metabolic process metabolic process	-

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B, C, D	IPR005887	Glycosyl hydrolase family 92, alpha-1,2-mannosidase, putative	Family
A, B, C, D	IPR008928	Six-hairpin glycosidase superfamily	Homologous Superfamily
A, B, C, D	IPR014718	Glycoside hydrolase-type carbohydrate-binding	Homologous Superfamily
A, B, C, D	IPR012939	Glycosyl hydrolase family 92	Domain
A, B, C, D	IPR041371	Glycosyl hydrolase family 92 N-terminal domain	Domain

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.