Domain Annotation: ECOD Classification ECOD Database Homepage

ChainsFamily NameDomain Identifier ArchitecturePossible HomologyHomologyTopologyFamilyProvenance Source (Version)
APNPasee6d6kA3 A: alpha arraysX: HTHH: Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 (From Topology)T: Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3F: PNPaseECOD (1.6)
ARNase_PHe6d6kA5 A: a+b two layersX: Ribosomal protein S5 domain 2-like (From Topology)H: Ribosomal protein S5 domain 2-like (From Topology)T: Ribosomal protein S5 domain 2-likeF: RNase_PHECOD (1.6)
ARNase_PH_1e6d6kA4 A: a+b two layersX: Ribosomal protein S5 domain 2-like (From Topology)H: Ribosomal protein S5 domain 2-like (From Topology)T: Ribosomal protein S5 domain 2-likeF: RNase_PH_1ECOD (1.6)
ARNase_PH_C_2e6d6kA1 A: a+b two layersX: Ribonuclease PH domain 2-likeH: Ribonuclease PH domain 2 (From Topology)T: Ribonuclease PH domain 2F: RNase_PH_C_2ECOD (1.6)
ARNase_PH_Ce6d6kA2 A: a+b two layersX: Ribonuclease PH domain 2-likeH: Ribonuclease PH domain 2 (From Topology)T: Ribonuclease PH domain 2F: RNase_PH_CECOD (1.6)
BPNPasee6d6kB2 A: alpha arraysX: HTHH: Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 (From Topology)T: Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3F: PNPaseECOD (1.6)
BRNase_PHe6d6kB4 A: a+b two layersX: Ribosomal protein S5 domain 2-like (From Topology)H: Ribosomal protein S5 domain 2-like (From Topology)T: Ribosomal protein S5 domain 2-likeF: RNase_PHECOD (1.6)
BRNase_PH_1e6d6kB5 A: a+b two layersX: Ribosomal protein S5 domain 2-like (From Topology)H: Ribosomal protein S5 domain 2-like (From Topology)T: Ribosomal protein S5 domain 2-likeF: RNase_PH_1ECOD (1.6)
BRNase_PH_C_2e6d6kB3 A: a+b two layersX: Ribonuclease PH domain 2-likeH: Ribonuclease PH domain 2 (From Topology)T: Ribonuclease PH domain 2F: RNase_PH_C_2ECOD (1.6)
BRNase_PH_Ce6d6kB1 A: a+b two layersX: Ribonuclease PH domain 2-likeH: Ribonuclease PH domain 2 (From Topology)T: Ribonuclease PH domain 2F: RNase_PH_CECOD (1.6)

Protein Family Annotation Pfam Database Homepage

ChainsAccessionNameDescriptionCommentsSource
A, B
PF03726Polyribonucleotide nucleotidyltransferase, RNA binding domain (PNPase)Polyribonucleotide nucleotidyltransferase, RNA binding domainThis family contains the RNA binding domain of Polyribonucleotide nucleotidyltransferase (PNPase) PNPase is involved in mRNA degradation in a 3'-5' direction.Domain
A, B
PF037253' exoribonuclease family, domain 2 (RNase_PH_C)3' exoribonuclease family, domain 2This family includes 3'-5' exoribonucleases. Ribonuclease PH contains a single copy of this domain, and removes nucleotide residues following the -CCA terminus of tRNA. Polyribonucleotide nucleotidyltransferase (PNPase) contains two tandem copies of ...This family includes 3'-5' exoribonucleases. Ribonuclease PH contains a single copy of this domain, and removes nucleotide residues following the -CCA terminus of tRNA. Polyribonucleotide nucleotidyltransferase (PNPase) contains two tandem copies of the domain. PNPase is involved in mRNA degradation in a 3'-5' direction. The exosome is a 3'-5' exoribonuclease complex that is required for 3' processing of the 5.8S rRNA. Three of its five protein components, Swiss:P46948 Swiss:Q12277 and Swiss:P25359 contain a copy of this domain [1]. Swiss:Q10205, a hypothetical protein from S. pombe appears to belong to an uncharacterised subfamily. This subfamily is found in both eukaryotes and archaebacteria.
Domain
A, B
PF00013KH domain (KH_1)KH domainKH motifs bind RNA in vitro. Autoantibodies to Nova, a KH domain protein, cause paraneoplastic opsoclonus ataxia.Domain
A, B
PF011383' exoribonuclease family, domain 1 (RNase_PH)3' exoribonuclease family, domain 1This family includes 3'-5' exoribonucleases. Ribonuclease PH contains a single copy of this domain, and removes nucleotide residues following the -CCA terminus of tRNA. Polyribonucleotide nucleotidyltransferase (PNPase) contains two tandem copies of ...This family includes 3'-5' exoribonucleases. Ribonuclease PH contains a single copy of this domain, and removes nucleotide residues following the -CCA terminus of tRNA. Polyribonucleotide nucleotidyltransferase (PNPase) contains two tandem copies of the domain. PNPase is involved in mRNA degradation in a 3'-5' direction. The exosome is a 3'-5' exoribonuclease complex that is required for 3' processing of the 5.8S rRNA. Three of its five protein components, Swiss:P46948 Swiss:Q12277 and Swiss:P25359 contain a copy of this domain [1]. Swiss:Q10205, a hypothetical protein from S. pombe appears to belong to an uncharacterised subfamily. This subfamily is found in both eukaryotes and archaebacteria.
Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

ChainsPolymerMolecular FunctionBiological ProcessCellular Component
A, B
Polyribonucleotide nucleotidyltransferase