6BUG

Crystal structure of a membrane protein, crystal form I

External Resource: Annotation

Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification
Membrane Protein Annotation: OPM
Membrane Protein Annotation: PDBTM
Membrane Protein Annotation: MemProtMD
Membrane Protein Annotation: mpstruc
Protein Modification Annotation

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2B Superfamily	ACP-like	8099694	3001805	SCOP2B (2022-06-29)
C [auth B]	SCOP2B Superfamily	ACP-like	8099694	3001805	SCOP2B (2022-06-29)
E	SCOP2B Superfamily	ACP-like	8099694	3001805	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
B [auth C]	F_UNCLASSIFIED	e6bugC2	A: alpha bundles	X: central core domain of D-alanyl transfer protein (From Topology)	H: central core domain of D-alanyl transfer protein (From Topology)	T: central core domain of D-alanyl transfer protein	F: F_UNCLASSIFIED	ECOD (1.6)
B [auth C]	F_UNCLASSIFIED	e6bugC1	A: alpha bundles	X: helical ridge domain of D-alanyl transfer protein (From Topology)	H: helical ridge domain of D-alanyl transfer protein (From Topology)	T: helical ridge domain of D-alanyl transfer protein	F: F_UNCLASSIFIED	ECOD (1.6)
F	F_UNCLASSIFIED	e6bugF1	A: alpha bundles	X: central core domain of D-alanyl transfer protein (From Topology)	H: central core domain of D-alanyl transfer protein (From Topology)	T: central core domain of D-alanyl transfer protein	F: F_UNCLASSIFIED	ECOD (1.6)
F	F_UNCLASSIFIED	e6bugF2	A: alpha bundles	X: helical ridge domain of D-alanyl transfer protein (From Topology)	H: helical ridge domain of D-alanyl transfer protein (From Topology)	T: helical ridge domain of D-alanyl transfer protein	F: F_UNCLASSIFIED	ECOD (1.6)
G	F_UNCLASSIFIED	e6bugG1	A: alpha bundles	X: central core domain of D-alanyl transfer protein (From Topology)	H: central core domain of D-alanyl transfer protein (From Topology)	T: central core domain of D-alanyl transfer protein	F: F_UNCLASSIFIED	ECOD (1.6)
G	F_UNCLASSIFIED	e6bugG2	A: alpha bundles	X: helical ridge domain of D-alanyl transfer protein (From Topology)	H: helical ridge domain of D-alanyl transfer protein (From Topology)	T: helical ridge domain of D-alanyl transfer protein	F: F_UNCLASSIFIED	ECOD (1.6)
D	F_UNCLASSIFIED	e6bugD1	A: alpha bundles	X: central core domain of D-alanyl transfer protein (From Topology)	H: central core domain of D-alanyl transfer protein (From Topology)	T: central core domain of D-alanyl transfer protein	F: F_UNCLASSIFIED	ECOD (1.6)
D	F_UNCLASSIFIED	e6bugD2	A: alpha bundles	X: helical ridge domain of D-alanyl transfer protein (From Topology)	H: helical ridge domain of D-alanyl transfer protein (From Topology)	T: helical ridge domain of D-alanyl transfer protein	F: F_UNCLASSIFIED	ECOD (1.6)
A	PF00550	e6bugA1	A: alpha bundles	X: ACP-like	H: Acyl-carrier protein (ACP) (From Topology)	T: Acyl-carrier protein (ACP)	F: PF00550	ECOD (1.6)
C [auth B]	PF00550	e6bugB1	A: alpha bundles	X: ACP-like	H: Acyl-carrier protein (ACP) (From Topology)	T: Acyl-carrier protein (ACP)	F: PF00550	ECOD (1.6)
E	PF00550	e6bugE1	A: alpha bundles	X: ACP-like	H: Acyl-carrier protein (ACP) (From Topology)	T: Acyl-carrier protein (ACP)	F: PF00550	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	1.10.1200.10	Mainly Alpha	Orthogonal Bundle	Non-ribosomal Peptide Synthetase Peptidyl Carrier Protein	Chain A	CATH (4.3.0)
C [auth B]	1.10.1200.10	Mainly Alpha	Orthogonal Bundle	Non-ribosomal Peptide Synthetase Peptidyl Carrier Protein	Chain A	CATH (4.3.0)
E	1.10.1200.10	Mainly Alpha	Orthogonal Bundle	Non-ribosomal Peptide Synthetase Peptidyl Carrier Protein	Chain A	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
B [auth C], D, F, G	PF03062	MBOAT, membrane-bound O-acyltransferase family (MBOAT)	MBOAT, membrane-bound O-acyltransferase family	-	Family
A, C [auth B], E	PF00550	Phosphopantetheine attachment site (PP-binding)	Phosphopantetheine attachment site	A 4'-phosphopantetheine prosthetic group is attached through a serine. This prosthetic group acts as a a 'swinging arm' for the attachment of activated fatty acid and amino-acid groups. This domain forms a four helix bundle. This family includes memb ...	A 4'-phosphopantetheine prosthetic group is attached through a serine. This prosthetic group acts as a a 'swinging arm' for the attachment of activated fatty acid and amino-acid groups. This domain forms a four helix bundle. This family includes members not included in Prosite. The inclusion of these members is supported by sequence analysis and functional evidence. The related domain of Swiss:P19828 has the attachment serine replaced by an alanine.	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
B [auth C], D, F, G	D-alanyl transfer protein DltB	acyltransferase activity transferase activity catalytic activity	teichoic acid biosynthetic process cellular biosynthetic process lipoteichoic acid metabolic process cell wall organization or biogenesis carbohydrate derivative metabolic process organic acid biosynthetic process organic acid metabolic process cellular component biogenesis organic substance metabolic process organic substance biosynthetic process small molecule metabolic process cellular component organization or biogenesis carbohydrate derivative biosynthetic process peptidoglycan-based cell wall biogenesis teichoic acid biosynthetic process cellular biosynthetic process lipoteichoic acid metabolic process cell wall organization or biogenesis carbohydrate derivative metabolic process organic acid biosynthetic process organic acid metabolic process cellular component biogenesis organic substance metabolic process organic substance biosynthetic process small molecule metabolic process cellular component organization or biogenesis carbohydrate derivative biosynthetic process peptidoglycan-based cell wall biogenesis small molecule biosynthetic process cellular metabolic process macromolecule biosynthetic process cell wall biogenesis biosynthetic process cell wall macromolecule biosynthetic process lipoteichoic acid biosynthetic process metabolic process cellular process macromolecule metabolic process teichoic acid metabolic process	cell periphery plasma membrane membrane cellular anatomical entity
A, C [auth B], E	D-alanyl carrier protein	phosphopantetheine-dependent carrier activity D-alanyl carrier activity molecular carrier activity	cellular component organization cell wall organization or biogenesis cell wall organization cellular process cellular component organization or biogenesis external encapsulating structure organization teichoic acid biosynthetic process cellular biosynthetic process lipoteichoic acid metabolic process carbohydrate derivative metabolic process organic acid biosynthetic process organic acid metabolic process cellular component biogenesis organic substance metabolic process cellular component organization cell wall organization or biogenesis cell wall organization cellular process cellular component organization or biogenesis external encapsulating structure organization teichoic acid biosynthetic process cellular biosynthetic process lipoteichoic acid metabolic process carbohydrate derivative metabolic process organic acid biosynthetic process organic acid metabolic process cellular component biogenesis organic substance metabolic process organic substance biosynthetic process small molecule metabolic process carbohydrate derivative biosynthetic process peptidoglycan-based cell wall biogenesis small molecule biosynthetic process cellular metabolic process macromolecule biosynthetic process cell wall biogenesis biosynthetic process cell wall macromolecule biosynthetic process lipoteichoic acid biosynthetic process metabolic process macromolecule metabolic process teichoic acid metabolic process	intracellular anatomical structure cytoplasm cellular anatomical entity

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
B [auth C], D, F, G	IPR004299	Membrane bound O-acyl transferase, MBOAT	Family
B [auth C], D, F, G	IPR024194	Alginate O-acetyltransferase AlgI/D-alanyl transfer protein DltB	Family
B [auth C], D, F, G	IPR024024	D-alanyl transfer protein DltB	Family
A, C [auth B], E	IPR009081	Phosphopantetheine binding ACP domain	Domain
A, C [auth B], E	IPR036736	ACP-like superfamily	Homologous Superfamily
A, C [auth B], E	IPR003230	D-alanyl carrier protein	Family

Membrane Protein Annotation: OPM OPM Database Homepage

Chains	External Link	Type	Class	Superfamily	Family
B [auth C], D, F, G	OPM				Membrane-bound O-acyltransferase

Membrane Protein Annotation: PDBTM PDBTM Database Homepage

Chains	External Link	Comment
B [auth C], D, F, G	PDBTM	Annotated as membrane protein by PDBTM

Membrane Protein Annotation: MemProtMD MemProtMD Database Homepage

Chains	External Link	Comment
B [auth C], D, F, G	MemProtMD	Annotated as membrane protein by MemProtMD

Membrane Protein Annotation: mpstruc mpstruc Database Homepage

Chains	Resource Link	Group	Subgroup	Protein
B [auth C], D, F, G	mpstruc	TRANSMEMBRANE PROTEINS: ALPHA-HELICAL	O-acyltransferases	DltB O-acyltransferase, crystal form I

Protein Modification Annotation

Modified Residue(s)
Chain	Residue(s)	Description
A, C [auth B], E	SEP	Parent Component: SER RESID: AA0037 PSI-MOD : O-phospho-L-serine MOD:00046

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.