Annotations: 5ZYS

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	PDZ	e5zysA1	A: beta barrels	X: PDZ domain (From Topology)	H: PDZ domain (From Topology)	T: PDZ domain	F: PDZ	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	2.30.42.10	Mainly Beta	Roll	Pdz3 Domain	PDZ domain	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A	PF16666	Unstructured region on MAGI (MAGI_u5)	Unstructured region on MAGI	-	Disordered
A	PF00595	PDZ domain (PDZ)	PDZ domain	PDZ domains are found in diverse signaling proteins.	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1	binding adenyl ribonucleotide binding nucleotide binding purine ribonucleotide binding purine ribonucleoside triphosphate binding nucleoside phosphate binding ion binding purine nucleotide binding organic cyclic compound binding anion binding adenyl nucleotide binding ATP binding heterocyclic compound binding carbohydrate derivative binding binding adenyl ribonucleotide binding nucleotide binding purine ribonucleotide binding purine ribonucleoside triphosphate binding nucleoside phosphate binding ion binding purine nucleotide binding organic cyclic compound binding anion binding adenyl nucleotide binding ATP binding heterocyclic compound binding carbohydrate derivative binding ribonucleotide binding small molecule binding cytoskeletal protein binding protein binding alpha-actinin binding actinin binding	regulation of biological process regulation of cellular process positive regulation of cell adhesion regulation of cell adhesion biological regulation positive regulation of biological process positive regulation of cell-cell adhesion cell adhesion cell-cell adhesion regulation of cell-cell adhesion cellular process positive regulation of cellular process cellular response to stimulus response to stimulus regulation of biological process regulation of cellular process positive regulation of cell adhesion regulation of cell adhesion biological regulation positive regulation of biological process positive regulation of cell-cell adhesion cell adhesion cell-cell adhesion regulation of cell-cell adhesion cellular process positive regulation of cellular process cellular response to stimulus response to stimulus signaling signal transduction cell communication	cell-cell junction adherens junction anchoring junction cell junction cellular anatomical entity membrane-bounded organelle intracellular anatomical structure nucleus membrane-enclosed lumen intracellular membrane-bounded organelle nucleolus intracellular organelle lumen intracellular organelle organelle lumen cell-cell junction adherens junction anchoring junction cell junction cellular anatomical entity membrane-bounded organelle intracellular anatomical structure nucleus membrane-enclosed lumen intracellular membrane-bounded organelle nucleolus intracellular organelle lumen intracellular organelle organelle lumen organelle intracellular non-membrane-bounded organelle nuclear lumen non-membrane-bounded organelle membrane apical junction complex bicellular tight junction tight junction cell periphery plasma membrane cytoplasm nucleoplasm cell projection
B	Nephrin	-	-	-

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A	IPR008145	Guanylate kinase/L-type calcium channel beta subunit	Domain
A	IPR036034	PDZ superfamily	Homologous Superfamily
A	IPR036020	WW domain superfamily	Homologous Superfamily
A	IPR020590	Guanylate kinase, conserved site	Conserved Site
A	IPR008144	Guanylate kinase-like domain	Domain
A	IPR001478	PDZ domain	Domain
A	IPR001202	WW domain	Domain
A	IPR027417	P-loop containing nucleoside triphosphate hydrolase	Homologous Superfamily

RCSB PDB Core Operations are funded by the National Science Foundation (DBI-1832184), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.