5ZVL

Crystal Structure of Wheat Glutarredoxin

External Resource: Annotation

Domain Annotation: SCOP/SCOPe Classification
Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A	d5zvla1	Alpha and beta proteins (a/b)	Thioredoxin fold	Thioredoxin-like	automated matches	automated matches	Wheat (Triticum aestivum ) [TaxId: 4565 ],	SCOPe (2.08)
A	d5zvla2	Artifacts	Tags	Tags	Tags	N-terminal Tags	Wheat (Triticum aestivum ) [TaxId: 4565 ],	SCOPe (2.08)
B	d5zvlb1	Alpha and beta proteins (a/b)	Thioredoxin fold	Thioredoxin-like	automated matches	automated matches	Wheat (Triticum aestivum ) [TaxId: 4565 ],	SCOPe (2.08)
B	d5zvlb2	Artifacts	Tags	Tags	Tags	N-terminal Tags	Wheat (Triticum aestivum ) [TaxId: 4565 ],	SCOPe (2.08)
C	d5zvlc1	Alpha and beta proteins (a/b)	Thioredoxin fold	Thioredoxin-like	automated matches	automated matches	Wheat (Triticum aestivum ) [TaxId: 4565 ],	SCOPe (2.08)
C	d5zvlc2	Artifacts	Tags	Tags	Tags	N-terminal Tags	Wheat (Triticum aestivum ) [TaxId: 4565 ],	SCOPe (2.08)
D	d5zvld1	Alpha and beta proteins (a/b)	Thioredoxin fold	Thioredoxin-like	automated matches	automated matches	Wheat (Triticum aestivum ) [TaxId: 4565 ],	SCOPe (2.08)
D	d5zvld2	Artifacts	Tags	Tags	Tags	N-terminal Tags	Wheat (Triticum aestivum ) [TaxId: 4565 ],	SCOPe (2.08)
E	d5zvle1	Alpha and beta proteins (a/b)	Thioredoxin fold	Thioredoxin-like	automated matches	automated matches	Wheat (Triticum aestivum ) [TaxId: 4565 ],	SCOPe (2.08)
E	d5zvle2	Artifacts	Tags	Tags	Tags	N-terminal Tags	Wheat (Triticum aestivum ) [TaxId: 4565 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2B Superfamily	Thioredoxin-like	8096748	3000031	SCOP2B (2022-06-29)
B	SCOP2B Superfamily	Thioredoxin-like	8096748	3000031	SCOP2B (2022-06-29)
C	SCOP2 Family	Thioltransferase	8096747	4000237	SCOP2 (2022-06-29)
C	SCOP2 Superfamily	Thioredoxin-like	8096748	3000031	SCOP2 (2022-06-29)
D	SCOP2B Superfamily	Thioredoxin-like	8096748	3000031	SCOP2B (2022-06-29)
E	SCOP2B Superfamily	Thioredoxin-like	8096748	3000031	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	PF00462	e5zvlA1	A: a+b three layers	X: Thioredoxin-like	H: Thioredoxin-like (From Topology)	T: Thioredoxin-like	F: PF00462	ECOD (1.6)
B	PF00462	e5zvlB1	A: a+b three layers	X: Thioredoxin-like	H: Thioredoxin-like (From Topology)	T: Thioredoxin-like	F: PF00462	ECOD (1.6)
C	PF00462	e5zvlC1	A: a+b three layers	X: Thioredoxin-like	H: Thioredoxin-like (From Topology)	T: Thioredoxin-like	F: PF00462	ECOD (1.6)
D	PF00462	e5zvlD1	A: a+b three layers	X: Thioredoxin-like	H: Thioredoxin-like (From Topology)	T: Thioredoxin-like	F: PF00462	ECOD (1.6)
E	PF00462	e5zvlE1	A: a+b three layers	X: Thioredoxin-like	H: Thioredoxin-like (From Topology)	T: Thioredoxin-like	F: PF00462	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	3.40.30.10	Alpha Beta	3-Layer(aba) Sandwich	Glutaredoxin	Glutaredoxin	CATH (4.3.0)
B	3.40.30.10	Alpha Beta	3-Layer(aba) Sandwich	Glutaredoxin	Glutaredoxin	CATH (4.3.0)
C	3.40.30.10	Alpha Beta	3-Layer(aba) Sandwich	Glutaredoxin	Glutaredoxin	CATH (4.3.0)
D	3.40.30.10	Alpha Beta	3-Layer(aba) Sandwich	Glutaredoxin	Glutaredoxin	CATH (4.3.0)
E	3.40.30.10	Alpha Beta	3-Layer(aba) Sandwich	Glutaredoxin	Glutaredoxin	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B, C, D, E	PF00462	Glutaredoxin (Glutaredoxin)	Glutaredoxin	-	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B, C, D, E	Glutaredoxin	oxidoreductase activity, acting on a sulfur group of donors disulfide oxidoreductase activity oxidoreductase activity glutathione disulfide oxidoreductase activity catalytic activity	cellular response to stimulus response to oxidative stress cellular response to chemical stimulus response to stimulus cellular response to stress response to stress response to chemical cellular response to oxidative stress cellular process cellular response to chemical stress	intracellular anatomical structure cytoplasm cellular anatomical entity

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B, C, D, E	IPR011899	Glutaredoxin, eukaryotic/virial	Domain
A, B, C, D, E	IPR011767	Glutaredoxin active site	Active Site
A, B, C, D, E	IPR014025	Glutaredoxin subgroup	Domain
A, B, C, D, E	IPR002109	Glutaredoxin	Domain
A, B, C, D, E	IPR036249	Thioredoxin-like superfamily	Homologous Superfamily

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.